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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AMBRA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006914 autophagy IEA GO:0007275 multicellular organismal development IEA GO:0007399 nervous system development IEA GO:0008285 negative regulation of cell proliferation IEA GO:0009790 embryo development IEA GO:0021915 neural tube development IEA GO:0030154 cell differentiation IEA GO:0043065 positive regulation of apoptosis IEA cellular_component GO:0005737 cytoplasm IDA GO:0005776 autophagic vacuole IEA GO:0031410 cytoplasmic vesicle IEA molecular_function

Protein-protein interaction details for AMBRA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID USP50 Affinity Capture-MS physical 19615732 DDB1 Affinity Capture-MS physical 16949367 DDB1 Reconstituted Complex physical 16949367 CUL4A Reconstituted Complex physical 16949367 CUL4B Reconstituted Complex physical 16949367 DDB1 Affinity Capture-MS physical 20562859 MAP1B Affinity Capture-MS physical 20562859 ATG3 Affinity Capture-MS physical 20562859 ATG4B Affinity Capture-MS physical 20562859 DDA1 Affinity Capture-MS physical 20562859 BECN1 Affinity Capture-MS physical 20562859 DDA1 Affinity Capture-MS physical 20562859 PARK2 Affinity Capture-Western physical 21753002 PARK2 Affinity Capture-Western physical 21753002 PARK2 Affinity Capture-MS physical 21753002 UBC Affinity Capture-MS physical 16196087 UBC Affinity Capture-MS physical 21987572