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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PRKCD (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006468 protein phosphorylation IDA GO:0006468 protein phosphorylation TAS GO:0006915 apoptosis IDA GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0007165 signal transduction TAS GO:0007202 activation of phospholipase C activity TAS GO:0007596 blood coagulation TAS GO:0010469 regulation of receptor activity TAS GO:0016064 immunoglobulin mediated immune response IEA GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0018107 peptidyl-threonine phosphorylation IDA GO:0019221 cytokine-mediated signaling pathway TAS GO:0023021 termination of signal transduction IMP GO:0030168 platelet activation TAS GO:0032091 negative regulation of protein binding TAS GO:0032613 interleukin-10 production IEA GO:0032615 interleukin-12 production IEA GO:0035307 positive regulation of protein dephosphorylation IMP GO:0035556 intracellular signal transduction IEA GO:0042100 B cell proliferation IEA GO:0042119 neutrophil activation IDA GO:0043085 positive regulation of catalytic activity IDA GO:0043407 negative regulation of MAP kinase activity IMP GO:0046627 negative regulation of insulin receptor signaling pathway ISS GO:0046627 negative regulation of insulin receptor signaling pathway TAS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050728 negative regulation of inflammatory response IC GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation ISS GO:0050821 protein stabilization NAS GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0090398 cellular senescence IMP GO:2000304 positive regulation of ceramide biosynthetic process IMP GO:2000753 positive regulation of glucosylceramide catabolic process IMP GO:2000755 positive regulation of sphingomyelin catabolic process IMP cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005783 endoplasmic reticulum IDA GO:0005829 cytosol IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005911 cell-cell junction IEA GO:0016363 nuclear matrix IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity TAS GO:0004674 protein serine/threonine kinase activity IDA GO:0004699 calcium-independent protein kinase C activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008022 protein C-terminus binding IPI GO:0008047 enzyme activator activity IDA GO:0019899 enzyme binding IPI GO:0043560 insulin receptor substrate binding ISS GO:0046872 metal ion binding IEA

Protein-protein interaction details for PRKCD (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RASGRP3 Biochemical Activity physical 15213298 RASGRP3 Affinity Capture-Western physical 15213298 RASGRP3 Affinity Capture-Western physical 15213298 PLSCR3 Biochemical Activity physical 12649167 INPP5D Affinity Capture-Western physical 12024011 SHC1 Affinity Capture-Western physical 12024011 SHC1 Reconstituted Complex physical 12024011 RIPK4 Affinity Capture-Western physical 10948194 YWHAG Affinity Capture-Western physical 10433554 PDPK1 Two-hybrid physical 11781095 PDPK1 Affinity Capture-Western physical 11781095 C1QBP Reconstituted Complex physical 10831594 C1QBP Affinity Capture-Western physical 10831594 GNA12 Biochemical Activity physical 8824244 GNA13 Biochemical Activity physical 8824244 MTOR Affinity Capture-Western physical 10698949 MTOR Affinity Capture-Western physical 10698949 STAT1 Affinity Capture-Western physical 12807916 STAT1 Affinity Capture-Western physical 12807916 PTK2B Affinity Capture-Western physical 11352632 ADAM9 Affinity Capture-Western physical 9857183 INSR Affinity Capture-Western physical 11266508 PDP1 Affinity Capture-Western physical 11577086 PDP2 Affinity Capture-Western physical 11577086 PPP2CA Biochemical Activity physical 11959144 IRS1 Affinity Capture-Western physical 12031982 INSR Affinity Capture-Western physical 12031982 PIK3CB Affinity Capture-Western physical 11676480 PTPN6 Affinity Capture-Western physical 11723252 PTPN6 Affinity Capture-Western physical 11723252 PTPN6 Reconstituted Complex physical 11723252 PTPN6 Biochemical Activity physical 11723252 YWHAZ Affinity Capture-Western physical 11950841 TIAM1 Biochemical Activity physical 10212259 PLD2 Affinity Capture-Western physical 11744693 PLD2 Reconstituted Complex physical 11744693 AFAP1 Reconstituted Complex physical 12134071 IL6ST Affinity Capture-Western physical 12361954 MUC1 Affinity Capture-Western physical 11877440 MUC1 Reconstituted Complex physical 11877440 MUC1 Biochemical Activity physical 11877440 GABRA1 Affinity Capture-Western physical 12091471 IRS1 Biochemical Activity physical 15516986 CHUK Reconstituted Complex physical 10022904 IKBKB Reconstituted Complex physical 10022904 IKBKB Affinity Capture-Western physical 10022904 IKBKB Affinity Capture-Western physical 10022904 CHUK Affinity Capture-Western physical 10022904 CHUK Affinity Capture-Western physical 10022904 IKBKB Biochemical Activity physical 10022904 SP1 Affinity Capture-Western physical 21159880 SP1 Affinity Capture-Western physical 21159880 SP1 Protein-peptide physical 21159880 NFE2L2 Biochemical Activity physical 19920073 PRKCD Biochemical Activity physical 19920073 NFE2L2 Affinity Capture-Western physical 19920073 UBC Affinity Capture-Western physical 19903772 HDAC5 Biochemical Activity physical 21146494 STAT3 Affinity Capture-Western physical 10446219 STAT3 Biochemical Activity physical 10446219 TRIM41 Affinity Capture-Western physical 17893151