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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PRNP (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001933 negative regulation of protein phosphorylation ISS GO:0006878 cellular copper ion homeostasis NAS GO:0006916 anti-apoptosis IEA GO:0006979 response to oxidative stress ISS GO:0007049 cell cycle IEA GO:0007050 cell cycle arrest IEA GO:0007411 axon guidance TAS GO:0008152 metabolic process TAS GO:0032689 negative regulation of interferon-gamma production ISS GO:0032700 negative regulation of interleukin-17 production ISS GO:0032703 negative regulation of interleukin-2 production ISS GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity ISS GO:0046007 negative regulation of activated T cell proliferation ISS GO:0046686 response to cadmium ion IEA GO:0046688 response to copper ion IEA GO:0050860 negative regulation of T cell receptor signaling pathway ISS GO:0051260 protein homooligomerization IEA GO:0070885 negative regulation of calcineurin-NFAT signaling pathway ISS cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm TAS GO:0005783 endoplasmic reticulum ISS GO:0005794 Golgi apparatus ISS GO:0005886 plasma membrane IEA GO:0005886 plasma membrane ISS GO:0019898 extrinsic to membrane TAS GO:0031225 anchored to membrane IEA GO:0045121 membrane raft ISS molecular_function GO:0005507 copper ion binding IDA GO:0005507 copper ion binding TAS GO:0005515 protein binding IPI GO:0008017 microtubule binding IDA GO:0015631 tubulin binding IDA GO:0042802 identical protein binding IPI GO:0043008 ATP-dependent protein binding IEA GO:0046872 metal ion binding IEA GO:0051087 chaperone binding IEA

Protein-protein interaction details for PRNP (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BAT3 Two-hybrid physical 16169070 STIP1 Reconstituted Complex physical 12093732 STIP1 Affinity Capture-Western physical 12093732 SRRM2 Affinity Capture-MS physical 16159877