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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BAD (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006007glucose catabolic processIEA
GO:0006915apoptosisTAS
GO:0006917induction of apoptosisIDA
GO:0006919activation of caspase activityIDA
GO:0006919activation of caspase activityISS
GO:0008543fibroblast growth factor receptor signaling pathwayTAS
GO:0008624induction of apoptosis by extracellular signalsIEA
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0008629induction of apoptosis by intracellular signalsIMP
GO:0008629induction of apoptosis by intracellular signalsTAS
GO:0008633activation of pro-apoptotic gene productsIMP
GO:0008633activation of pro-apoptotic gene productsTAS
GO:0010918positive regulation of mitochondrial membrane potentialIEA
GO:0010918positive regulation of mitochondrial membrane potentialISS
GO:0019221cytokine-mediated signaling pathwayIEA
GO:0032024positive regulation of insulin secretionISS
GO:0033133positive regulation of glucokinase activityIEA
GO:0033133positive regulation of glucokinase activityISS
GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulusIEA
GO:0042593glucose homeostasisIEA
GO:0042593glucose homeostasisISS
GO:0043065positive regulation of apoptosisIDA
GO:0043280positive regulation of caspase activityIDA
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic processIEA
GO:0044342type B pancreatic cell proliferationIEA
GO:0044342type B pancreatic cell proliferationISS
GO:0045579positive regulation of B cell differentiationIEA
GO:0045582positive regulation of T cell differentiationIEA
GO:0046031ADP metabolic processIEA
GO:0046031ADP metabolic processISS
GO:0046034ATP metabolic processIEA
GO:0046034ATP metabolic processISS
GO:0046902regulation of mitochondrial membrane permeabilityIMP
GO:0046931pore complex assemblyIDA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
GO:0050679positive regulation of epithelial cell proliferationIMP
GO:0060154cellular process regulating host cell cycle in response to virusIEA
GO:0071260cellular response to mechanical stimulusIEP
GO:0071316cellular response to nicotineIDA
GO:0071396cellular response to lipidIEA
GO:0071456cellular response to hypoxiaIEP
GO:2000078positive regulation of type B pancreatic cell developmentIEA
GO:2000078positive regulation of type B pancreatic cell developmentISS
cellular_component
GO:0005737cytoplasmIEA
GO:0005739mitochondrionIDA
GO:0005739mitochondrionIEA
GO:0005741mitochondrial outer membraneIDA
GO:0005741mitochondrial outer membraneTAS
GO:0005829cytosolIDA
GO:0005829cytosolIEA
GO:0005829cytosolTAS
GO:0016020membraneIEA
molecular_function
GO:0005515protein bindingIPI
GO:0005543phospholipid bindingIMP
GO:0008289lipid bindingIDA
GO:0008656caspase activator activityIDA
GO:0008656caspase activator activityIEA
GO:0019901protein kinase bindingIPI
GO:0019903protein phosphatase bindingIEA
GO:0046982protein heterodimerization activityIEA

Protein-protein interaction details for BAD (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
BCL2A1Two-hybridphysical11483855
MCL1Two-hybridphysical11483855
SFNTwo-hybridphysical16189514
EWSR1Two-hybridphysical16189514
BCL2L2Protein-peptidephysical15694340
MCL1Protein-peptidephysical15694340
BCL2A1Protein-peptidephysical15694340
BCL2L1Affinity Capture-Westernphysical15694340
BCL2Affinity Capture-Westernphysical15694340
YWHAQAffinity Capture-Westernphysical15694340
PRKCIReconstituted Complexphysical15705582
BCL2L1Affinity Capture-Westernphysical15705582
BCL2L1Affinity Capture-Westernphysical15705582
BCL2L1Affinity Capture-Westernphysical9824152
BCL2L1Protein-peptidephysical12137781
PIM2Biochemical Activityphysical12954615
YWHAETwo-hybridphysical9369453
YWHABTwo-hybridphysical9369453
YWHAQTwo-hybridphysical9369453
YWHAHTwo-hybridphysical9369453
S100A10Two-hybridphysical9369453
S100A10Reconstituted Complexphysical9369453
BCL2L1Affinity Capture-Westernphysical12115603
BCL2L2Affinity Capture-Westernphysical12115603
SNCAReconstituted Complexphysical11742726
BCL2L2Two-hybridphysical11483855
BCL2L2Reconstituted Complexphysical11483855
BCL2A1Reconstituted Complexphysical11483855
MCL1Reconstituted Complexphysical11483855
BCL2L1Two-hybridphysical10620799
AKT1Reconstituted Complexphysical11500364
PRKACAReconstituted Complexphysical11500364
RPS6KA1Reconstituted Complexphysical11500364
RPS6KA5Reconstituted Complexphysical11500364
BCL2Affinity Capture-Westernphysical7834748
BCL2L1Affinity Capture-Westernphysical7834748
BCL2Two-hybridphysical7834748
BCL2L1Two-hybridphysical7834748
BCL2L1Reconstituted Complexphysical11206074
YWHAZReconstituted Complexphysical11410287
YWHAZTwo-hybridphysical11410287
BCL2L1Affinity Capture-Westernphysical11494146
BCL2L2Affinity Capture-Westernphysical10381646
BCL2L1Two-hybridphysical9389483
BCL2L1Two-hybridphysical11077446
YWHAETwo-hybridphysical20936779
YWHAZTwo-hybridphysical20936779
YWHAGTwo-hybridphysical20936779
YWHAZAffinity Capture-Westernphysical21076048
YWHABTwo-hybridphysical21900206
SUMO2Two-hybridphysical21900206