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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for BAD (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006007
glucose catabolic process
IEA
GO:0006915
apoptosis
TAS
GO:0006917
induction of apoptosis
IDA
GO:0006919
activation of caspase activity
IDA
GO:0006919
activation of caspase activity
ISS
GO:0008543
fibroblast growth factor receptor signaling pathway
TAS
GO:0008624
induction of apoptosis by extracellular signals
IEA
GO:0008624
induction of apoptosis by extracellular signals
TAS
GO:0008629
induction of apoptosis by intracellular signals
IMP
GO:0008629
induction of apoptosis by intracellular signals
TAS
GO:0008633
activation of pro-apoptotic gene products
IMP
GO:0008633
activation of pro-apoptotic gene products
TAS
GO:0010918
positive regulation of mitochondrial membrane potential
IEA
GO:0010918
positive regulation of mitochondrial membrane potential
ISS
GO:0019221
cytokine-mediated signaling pathway
IEA
GO:0032024
positive regulation of insulin secretion
ISS
GO:0033133
positive regulation of glucokinase activity
IEA
GO:0033133
positive regulation of glucokinase activity
ISS
GO:0035774
positive regulation of insulin secretion involved in cellular response to glucose stimulus
IEA
GO:0042593
glucose homeostasis
IEA
GO:0042593
glucose homeostasis
ISS
GO:0043065
positive regulation of apoptosis
IDA
GO:0043280
positive regulation of caspase activity
IDA
GO:0043281
regulation of cysteine-type endopeptidase activity involved in apoptotic process
IEA
GO:0044342
type B pancreatic cell proliferation
IEA
GO:0044342
type B pancreatic cell proliferation
ISS
GO:0045579
positive regulation of B cell differentiation
IEA
GO:0045582
positive regulation of T cell differentiation
IEA
GO:0046031
ADP metabolic process
IEA
GO:0046031
ADP metabolic process
ISS
GO:0046034
ATP metabolic process
IEA
GO:0046034
ATP metabolic process
ISS
GO:0046902
regulation of mitochondrial membrane permeability
IMP
GO:0046931
pore complex assembly
IDA
GO:0048011
nerve growth factor receptor signaling pathway
TAS
GO:0048015
phosphatidylinositol-mediated signaling
TAS
GO:0050679
positive regulation of epithelial cell proliferation
IMP
GO:0060154
cellular process regulating host cell cycle in response to virus
IEA
GO:0071260
cellular response to mechanical stimulus
IEP
GO:0071316
cellular response to nicotine
IDA
GO:0071396
cellular response to lipid
IEA
GO:0071456
cellular response to hypoxia
IEP
GO:2000078
positive regulation of type B pancreatic cell development
IEA
GO:2000078
positive regulation of type B pancreatic cell development
ISS
cellular_component
GO:0005737
cytoplasm
IEA
GO:0005739
mitochondrion
IDA
GO:0005739
mitochondrion
IEA
GO:0005741
mitochondrial outer membrane
IDA
GO:0005741
mitochondrial outer membrane
TAS
GO:0005829
cytosol
IDA
GO:0005829
cytosol
IEA
GO:0005829
cytosol
TAS
GO:0016020
membrane
IEA
molecular_function
GO:0005515
protein binding
IPI
GO:0005543
phospholipid binding
IMP
GO:0008289
lipid binding
IDA
GO:0008656
caspase activator activity
IDA
GO:0008656
caspase activator activity
IEA
GO:0019901
protein kinase binding
IPI
GO:0019903
protein phosphatase binding
IEA
GO:0046982
protein heterodimerization activity
IEA
Protein-protein interaction details for BAD (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
BCL2A1
Two-hybrid
physical
11483855
MCL1
Two-hybrid
physical
11483855
SFN
Two-hybrid
physical
16189514
EWSR1
Two-hybrid
physical
16189514
BCL2L2
Protein-peptide
physical
15694340
MCL1
Protein-peptide
physical
15694340
BCL2A1
Protein-peptide
physical
15694340
BCL2L1
Affinity Capture-Western
physical
15694340
BCL2
Affinity Capture-Western
physical
15694340
YWHAQ
Affinity Capture-Western
physical
15694340
PRKCI
Reconstituted Complex
physical
15705582
BCL2L1
Affinity Capture-Western
physical
15705582
BCL2L1
Affinity Capture-Western
physical
15705582
BCL2L1
Affinity Capture-Western
physical
9824152
BCL2L1
Protein-peptide
physical
12137781
PIM2
Biochemical Activity
physical
12954615
YWHAE
Two-hybrid
physical
9369453
YWHAB
Two-hybrid
physical
9369453
YWHAQ
Two-hybrid
physical
9369453
YWHAH
Two-hybrid
physical
9369453
S100A10
Two-hybrid
physical
9369453
S100A10
Reconstituted Complex
physical
9369453
BCL2L1
Affinity Capture-Western
physical
12115603
BCL2L2
Affinity Capture-Western
physical
12115603
SNCA
Reconstituted Complex
physical
11742726
BCL2L2
Two-hybrid
physical
11483855
BCL2L2
Reconstituted Complex
physical
11483855
BCL2A1
Reconstituted Complex
physical
11483855
MCL1
Reconstituted Complex
physical
11483855
BCL2L1
Two-hybrid
physical
10620799
AKT1
Reconstituted Complex
physical
11500364
PRKACA
Reconstituted Complex
physical
11500364
RPS6KA1
Reconstituted Complex
physical
11500364
RPS6KA5
Reconstituted Complex
physical
11500364
BCL2
Affinity Capture-Western
physical
7834748
BCL2L1
Affinity Capture-Western
physical
7834748
BCL2
Two-hybrid
physical
7834748
BCL2L1
Two-hybrid
physical
7834748
BCL2L1
Reconstituted Complex
physical
11206074
YWHAZ
Reconstituted Complex
physical
11410287
YWHAZ
Two-hybrid
physical
11410287
BCL2L1
Affinity Capture-Western
physical
11494146
BCL2L2
Affinity Capture-Western
physical
10381646
BCL2L1
Two-hybrid
physical
9389483
BCL2L1
Two-hybrid
physical
11077446
YWHAE
Two-hybrid
physical
20936779
YWHAZ
Two-hybrid
physical
20936779
YWHAG
Two-hybrid
physical
20936779
YWHAZ
Affinity Capture-Western
physical
21076048
YWHAB
Two-hybrid
physical
21900206
SUMO2
Two-hybrid
physical
21900206