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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for USP28 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000077 DNA damage checkpoint IMP GO:0006281 DNA repair IEA GO:0006511 ubiquitin-dependent protein catabolic process IEA GO:0008283 cell proliferation IMP GO:0010212 response to ionizing radiation IDA GO:0016579 protein deubiquitination IDA GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis IDA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm IDA GO:0005730 nucleolus IDA molecular_function GO:0004221 ubiquitin thiolesterase activity IEA GO:0004221 ubiquitin thiolesterase activity IMP GO:0004843 ubiquitin-specific protease activity IDA GO:0005515 protein binding IPI GO:0008233 peptidase activity IEA GO:0008234 cysteine-type peptidase activity IEA

Protein-protein interaction details for USP28 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SUMO2 Affinity Capture-MS physical 19615732 TP53BP1 Affinity Capture-MS physical 19615732 AQR Affinity Capture-MS physical 19615732 USP25 Affinity Capture-MS physical 19615732 TP53BP1 Affinity Capture-MS physical 16901786 TP53BP1 Affinity Capture-Western physical 16901786 TP53BP1 Affinity Capture-Western physical 16901786 CLSPN Affinity Capture-Western physical 16901786 MDC1 Affinity Capture-Western physical 16901786 UBC Reconstituted Complex physical 19850743 PLA2G2A Biochemical Activity physical 22118674 UBC Affinity Capture-MS physical 22118674