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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BAK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001836release of cytochrome c from mitochondriaIDA
GO:0001836release of cytochrome c from mitochondriaIGI
GO:0006915apoptosisTAS
GO:0007420brain developmentIEA
GO:0007568agingIEA
GO:0008285negative regulation of cell proliferationIEA
GO:0008624induction of apoptosis by extracellular signalsIMP
GO:0008629induction of apoptosis by intracellular signalsTAS
GO:0008633activation of pro-apoptotic gene productsTAS
GO:0010225response to UV-CIEA
GO:0010248establishment or maintenance of transmembrane electrochemical gradientIDA
GO:0010629negative regulation of gene expressionIEA
GO:0014070response to organic cyclic compoundIEA
GO:0031018endocrine pancreas developmentIEA
GO:0031100organ regenerationIEA
GO:0034644cellular response to UVIMP
GO:0034644cellular response to UVISS
GO:0042493response to drugIEA
GO:0042542response to hydrogen peroxideIEA
GO:0042981regulation of apoptosisIEA
GO:0043496regulation of protein homodimerization activityIDA
GO:0043497regulation of protein heterodimerization activityIDA
GO:0045471response to ethanolIEA
GO:0046902regulation of mitochondrial membrane permeabilityIDA
GO:0051881regulation of mitochondrial membrane potentialIDA
GO:0071260cellular response to mechanical stimulusIEP
GO:0090200positive regulation of release of cytochrome c from mitochondriaIEA
cellular_component
GO:0005624membrane fractionIEA
GO:0005739mitochondrionIDA
GO:0005741mitochondrial outer membraneTAS
GO:0005829cytosolIEA
GO:0016020membraneIEA
GO:0031307integral to mitochondrial outer membraneISS
GO:0046930pore complexIDA
molecular_function
GO:0005515protein bindingIPI
GO:0031072heat shock protein bindingIEA
GO:0042802identical protein bindingIPI
GO:0046872metal ion bindingIEA
GO:0046982protein heterodimerization activityIPI
GO:0051087chaperone bindingIEA
GO:0051400BH domain bindingIEA

Protein-protein interaction details for BAK1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
BCL2L1Two-hybridphysical16189514
BCL2L1Affinity Capture-Westernphysical16189514
FRYLAffinity Capture-MSphysical17353931
AKAP13Affinity Capture-MSphysical17353931
FBLAffinity Capture-MSphysical17353931
SRRM2Affinity Capture-MSphysical17353931
KRT31Affinity Capture-MSphysical17353931
VDAC2Affinity Capture-MSphysical17353931
DFFAAffinity Capture-MSphysical17353931
ACTR2Affinity Capture-MSphysical17353931
MYCBP2Affinity Capture-MSphysical17353931
BAK1Affinity Capture-Westernphysical15077116
MCL1Reconstituted Complexphysical15077116
MCL1Affinity Capture-Westernphysical15077116
TP53Affinity Capture-Westernphysical15077116
TP53Reconstituted Complexphysical15077116
TP53Affinity Capture-MSphysical15077116
MCL1Affinity Capture-Westernphysical15901672
MCL1Protein-peptidephysical15901672
BCL2L1Protein-peptidephysical12137781
MCL1Reconstituted Complexphysical15637055
BCL2L1FRETphysical14596824
BCL2L1Affinity Capture-Westernphysical15901672
BCL2L1Protein-peptidephysical15901672
BCL2Affinity Capture-Westernphysical14980220
VDAC2Affinity Capture-Westernphysical12881569
BCL2L1Reconstituted Complexphysical11175750
HSPD1Affinity Capture-Westernphysical12070120
MCL1Two-hybridphysical10837489
BAXAffinity Capture-Westernphysical11571294
BCL2L2Affinity Capture-Westernphysical10381646
BCL2Protein-peptidephysical11728179
MCL1Reconstituted Complexphysical21613222
DBN1Two-hybridphysical21900206
ARHGDIATwo-hybridphysical21900206
UBCAffinity Capture-Westernphysical20930068