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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PURA (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006268DNA unwinding involved in replicationIDA
GO:0006270DNA-dependent DNA replication initiationTAS
GO:0007399nervous system developmentIEA
GO:0008284positive regulation of cell proliferationIEA
GO:0045892negative regulation of transcription, DNA-dependentIEA
cellular_component
GO:0000784nuclear chromosome, telomeric regionIC
GO:0005634nucleusIDA
GO:0005662DNA replication factor A complexISS
GO:0005737cytoplasmIEA
GO:0030425dendriteIEA
GO:0043025neuronal cell bodyIEA
molecular_function
GO:0000900translation repressor activity, nucleic acid bindingIEA
GO:0003677DNA bindingIEA
GO:0003691double-stranded telomeric DNA bindingIDA
GO:0003697single-stranded DNA bindingISS
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003705sequence-specific distal enhancer binding RNA polymerase II transcription factor activityTAS
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingISS
GO:0032422purine-rich negative regulatory element bindingIEA
GO:0046332SMAD bindingIEA

Protein-protein interaction details for PURA (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CNBPAffinity Capture-MSphysical17353931
CCNT1Reconstituted Complexphysical11730934
SP1Affinity Capture-Westernphysical10457364
E2F1Reconstituted Complexphysical10597240
E2F1Reconstituted Complexphysical10597240
HNRNPA1Affinity Capture-MSphysical17643375
MEPCEAffinity Capture-MSphysical17643375
UBCAffinity Capture-MSphysical16196087
POU5F1Affinity Capture-RNAphysical21151833
EIF2AK2Affinity Capture-MSphysical21903422