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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Shank3 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeIGI
GO:0001838embryonic epithelial tube formationIGI
GO:0007416synapse assemblyIMP
GO:0021773striatal medium spiny neuron differentiationIMP
GO:0035176social behaviorIMP
GO:0035641locomotory exploration behaviorIMP
GO:0045794negative regulation of cell volumeIMP
GO:0048854brain morphogenesisIMP
GO:0051259protein oligomerizationISO
GO:0051968positive regulation of synaptic transmission, glutamatergicIMP
GO:0060997dendritic spine morphogenesisIMP
GO:0097107postsynaptic density assemblyIMP
GO:2000463positive regulation of excitatory postsynaptic membrane potentialIMP
GO:2000821regulation of grooming behaviorIMP
GO:2000822regulation of behavioral fear responseIMP
GO:2000969positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityIMP
cellular_component
GO:0005737cytoplasmIEA
GO:0005886plasma membraneIDA
GO:0014069postsynaptic densityISO
GO:0016020membraneIEA
GO:0030054cell junctionIEA
GO:0044309neuron spineIDA
GO:0045202synapseISO
GO:0045211postsynaptic membraneIEA
GO:0060076excitatory synapseIC
molecular_function
GO:0005515protein bindingIPI
GO:0008022protein C-terminus bindingIPI
GO:0008022protein C-terminus bindingISO
GO:0008270zinc ion bindingISO
GO:0017124SH3 domain bindingISO
GO:0030160GKAP/Homer scaffold activityISO
GO:0035255ionotropic glutamate receptor bindingIPI
GO:0043621protein self-associationISO
GO:0097110scaffold protein bindingIPI
GO:0097110scaffold protein bindingISO

Protein-protein interaction details for Shank3 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
UbcAffinity Capture-Westernphysical21565394