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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RAD51 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000724 double-strand break repair via homologous recombination IDA GO:0000724 double-strand break repair via homologous recombination IEA GO:0000724 double-strand break repair via homologous recombination TAS GO:0000730 DNA recombinase assembly TAS GO:0006259 DNA metabolic process IEA GO:0006268 DNA unwinding involved in replication IDA GO:0006268 DNA unwinding involved in replication ISS GO:0006281 DNA repair IEA GO:0006281 DNA repair TAS GO:0006302 double-strand break repair TAS GO:0006310 DNA recombination TAS GO:0006312 mitotic recombination TAS GO:0007126 meiosis IEA GO:0007126 meiosis ISS GO:0007131 reciprocal meiotic recombination TAS GO:0051106 positive regulation of DNA ligation IDA GO:0051260 protein homooligomerization IPI cellular_component GO:0000793 condensed chromosome ISS GO:0000794 condensed nuclear chromosome IEA GO:0000794 condensed nuclear chromosome ISS GO:0000800 lateral element IEA GO:0005634 nucleus IDA GO:0005634 nucleus ISS GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005759 mitochondrial matrix IEA GO:0016605 PML body IDA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003684 damaged DNA binding IEA GO:0003690 double-stranded DNA binding IDA GO:0003690 double-stranded DNA binding ISS GO:0003697 single-stranded DNA binding IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0005524 ATP binding IEA GO:0008022 protein C-terminus binding IPI GO:0008094 DNA-dependent ATPase activity IEA GO:0017111 nucleoside-triphosphatase activity IEA GO:0042802 identical protein binding IPI GO:0043142 single-stranded DNA-dependent ATPase activity IDA

Protein-protein interaction details for RAD51 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BRCA2 Two-hybrid physical 9126738 RAD51AP1 Two-hybrid physical 9396801 DMC1 Two-hybrid physical 10562567 LGTN Affinity Capture-MS physical 17353931 CAB39 Affinity Capture-MS physical 17353931 TIMM13 Affinity Capture-MS physical 17353931 BRCA2 Affinity Capture-Western physical 12815053 BRCA2 Co-localization physical 14580352 BRCA2 Affinity Capture-Western physical 14580352 H2AFX Co-localization physical 10959836 BRCA1 Reconstituted Complex physical 9008167 BRCA2 Reconstituted Complex physical 9560268 BRCA2 Affinity Capture-Western physical 9560268 BRCA2 Two-hybrid physical 9560268 BARD1 Affinity Capture-MS physical 14636569 BARD1 Affinity Capture-Western physical 14636569 BRCA1 Affinity Capture-MS physical 14636569 BRCA1 Affinity Capture-Western physical 14636569 BRCA1 Co-purification physical 14636569 BRCA2 Affinity Capture-Western physical 14636569 BRCA2 Affinity Capture-MS physical 14636569 BRCA2 Co-purification physical 14636569 BRE Affinity Capture-MS physical 14636569 BRE Affinity Capture-Western physical 14636569 BRE Co-purification physical 14636569 BRCC3 Affinity Capture-MS physical 14636569 BRCC3 Affinity Capture-Western physical 14636569 BRCA2 Affinity Capture-Western physical 11477095 TP53 Affinity Capture-MS physical 14636569 TP53 Co-purification physical 14636569 TP53 Affinity Capture-Western physical 14636569 ABL1 Affinity Capture-Western physical 10212258 RAD52 Affinity Capture-Western physical 10212258 RAD52 Affinity Capture-Western physical 10212258 BRCA2 Two-hybrid physical 9405383 BRCA2 Reconstituted Complex physical 9405383 BRCA2 Affinity Capture-Western physical 9523196 BRCA2 Two-hybrid physical 9523196 BLM Affinity Capture-Western physical 11278509 BLM Two-hybrid physical 11278509 BLM Far Western physical 11278509 BRCA2 Reconstituted Complex physical 12442171 RAD51 Co-crystal Structure physical 12442171 RAD51 Affinity Capture-Western physical 12442171 BRCA2 Co-localization physical 15065660 RAD51L1 Co-localization physical 15065660 RAD51C Co-localization physical 15065660 RAD51L3 Co-localization physical 15065660 XRCC2 Co-localization physical 15065660 XRCC3 Co-localization physical 15065660 ABL1 Reconstituted Complex physical 10212258 ABL1 Affinity Capture-Western physical 10212258 ATM Affinity Capture-Western physical 10212258 ABL1 Affinity Capture-Western physical 10212258 ATM Affinity Capture-Western physical 10212258 BRCA1 Reconstituted Complex physical 11498787 BRCA2 Affinity Capture-Western physical 11313963 BRCC3 Co-purification physical 14636569 RAD51 Affinity Capture-Western physical 14580352 RAD51 Co-localization physical 14580352 VIM Two-hybrid physical 16169070 CHD3 Two-hybrid physical 16169070 RAD54B Affinity Capture-Western physical 10851248 RAD54B Affinity Capture-Western physical 10851248 RAD54B Reconstituted Complex physical 10851248 ATRX Reconstituted Complex physical 10851248 RAD51 Two-hybrid physical 10851248 ATRX Two-hybrid physical 10851248 BRCA2 Affinity Capture-Western physical 9774970 BRCA1 Reconstituted Complex physical 9774970 DMC1 Reconstituted Complex physical 10562567 DMC1 Two-hybrid physical 10562567 TP53 Reconstituted Complex physical 8617246 TP53 Affinity Capture-Western physical 8617246 RAD51AP1 Two-hybrid physical 9396801 RAD51AP1 Reconstituted Complex physical 9396801 BRCA2 Two-hybrid physical 9126738 DNAJA3 Co-localization physical 11005857 TP53 Reconstituted Complex physical 9380510 BRCA2 Affinity Capture-Western physical 9811893 SUMO1 Two-hybrid physical 8812453 ATRX Reconstituted Complex physical 12205100 UBE2I Two-hybrid physical 8610150 RAD51 Two-hybrid physical 8610150 RPA1 Reconstituted Complex physical 12077133 UBE2I Two-hybrid physical 8921390 MSH4 Co-localization physical 11950880 RAD18 Affinity Capture-Western physical 19396164 RAD18 Reconstituted Complex physical 19396164 ATRX Reconstituted Complex physical 15466868 TP53 Affinity Capture-Western physical 16983346 MCPH1 Co-localization physical 20107607 MCPH1 Affinity Capture-Western physical 19549900 MCPH1 Affinity Capture-Western physical 19549900 MCPH1 Co-localization physical 19549900 BRCA2 Affinity Capture-Western physical 15671039 BRCA2 Affinity Capture-Western physical 16914443 SP1 Affinity Capture-Western physical 18769160 RAD51C Affinity Capture-Western physical 16395335 RAD51C Co-localization physical 16395335 MDC1 Affinity Capture-Western physical 16186822 MDC1 Affinity Capture-Western physical 16186822 MDC1 Reconstituted Complex physical 16186822 PALB2 Reconstituted Complex physical 20871616 PALB2 Affinity Capture-MS physical 20332121 MORF4L1 Affinity Capture-Western physical 20332121 POLN Affinity Capture-Western physical 19995904 PALB2 Affinity Capture-Western physical 19584259 PALB2 Co-localization physical 19584259 WRN Affinity Capture-Western physical 17118963 WRN Affinity Capture-Western physical 17118963 WRN Reconstituted Complex physical 17118963 WRN Reconstituted Complex physical 17118963 RAD52 Reconstituted Complex physical 17118963 RAD52 Reconstituted Complex physical 17118963 WRN Far Western physical 17118963 BRCA2 Affinity Capture-Western physical 16793542 PALB2 Affinity Capture-Western physical 16793542 BRCA2 Affinity Capture-MS physical 16793542 RAD51AP1 Affinity Capture-Western physical 16920159 BRCA2 Co-localization physical 21076401 UHRF2 Far Western physical 21952639