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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RAP1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity TAS GO:0006112 energy reserve metabolic process TAS GO:0006184 GTP catabolic process TAS GO:0007165 signal transduction IEA GO:0007264 small GTPase mediated signal transduction IEA GO:0007596 blood coagulation TAS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050796 regulation of insulin secretion TAS cellular_component GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0032045 guanyl-nucleotide exchange factor complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0003924 GTPase activity IEA GO:0005515 protein binding IPI GO:0005525 GTP binding IEA GO:0017016 Ras GTPase binding IEA

Protein-protein interaction details for RAP1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PDE6D Two-hybrid physical 11786539 RAP1GDS1 Two-hybrid physical 11948427 KRIT1 Two-hybrid physical 9285558 RGL4 Reconstituted Complex physical 12874025 TSC2 Affinity Capture-Western physical 12842888 GABARAPL2 Biochemical Activity physical 12581858 ARHGEF1 Biochemical Activity physical 12581858 PDE6D Two-hybrid physical 11980706 RUNDC3A Reconstituted Complex physical 9523700 MLLT4 Two-hybrid physical 10922060 RALGDS Two-hybrid physical 10922060 MLLT4 Reconstituted Complex physical 10922060 RAPGEF3 Biochemical Activity physical 10777494 RAPGEF4 Biochemical Activity physical 10777494 RAPGEF5 Biochemical Activity physical 10777494 RALA Two-hybrid physical 11786539 MTOR Affinity Capture-Western physical 15854902 RAP1GAP Biochemical Activity physical 12842888 RHEB Affinity Capture-Western physical 15854902 TSC2 Co-purification physical 12147258 RAF1 Two-hybrid physical 7862125 RGS14 Reconstituted Complex physical 10926822 RALGDS Reconstituted Complex physical 10085114 RAF1 Co-crystal Structure physical 7791872 RAF1 Reconstituted Complex physical 9867809 BRAF Reconstituted Complex physical 10454553 RAF1 Reconstituted Complex physical 10454553 NTRK1 Affinity Capture-Western physical 11466412 RAPGEF5 Biochemical Activity physical 10934204 RAPGEF2 Biochemical Activity physical 10934204 RAPGEF2 Reconstituted Complex physical 10934204 RAPGEF6 Biochemical Activity physical 11524421 PPP2R1A Affinity Capture-MS physical 17540176