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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Tgfb1 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000060
protein import into nucleus, translocation
ISO
GO:0000060
protein import into nucleus, translocation
ISS
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IEA
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0001558
regulation of cell growth
TAS
GO:0001657
ureteric bud development
IEA
GO:0001666
response to hypoxia
IEP
GO:0001763
morphogenesis of a branching structure
IDA
GO:0001837
epithelial to mesenchymal transition
IDA
GO:0001933
negative regulation of protein phosphorylation
ISO
GO:0001933
negative regulation of protein phosphorylation
ISS
GO:0001934
positive regulation of protein phosphorylation
ISO
GO:0001934
positive regulation of protein phosphorylation
ISS
GO:0002028
regulation of sodium ion transport
IEA
GO:0002028
regulation of sodium ion transport
ISO
GO:0002062
chondrocyte differentiation
ISO
GO:0002062
chondrocyte differentiation
ISS
GO:0002244
hemopoietic progenitor cell differentiation
ISO
GO:0002244
hemopoietic progenitor cell differentiation
ISS
GO:0002460
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
IEA
GO:0002460
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
ISO
GO:0002513
tolerance induction to self antigen
IEA
GO:0002513
tolerance induction to self antigen
ISO
GO:0006468
protein phosphorylation
ISO
GO:0006611
protein export from nucleus
ISO
GO:0006611
protein export from nucleus
ISS
GO:0006754
ATP biosynthetic process
ISO
GO:0006754
ATP biosynthetic process
ISS
GO:0006796
phosphate-containing compound metabolic process
ISO
GO:0006796
phosphate-containing compound metabolic process
ISS
GO:0006874
cellular calcium ion homeostasis
IEA
GO:0006874
cellular calcium ion homeostasis
ISO
GO:0006917
induction of apoptosis
ISO
GO:0006917
induction of apoptosis
ISS
GO:0006954
inflammatory response
IEA
GO:0006954
inflammatory response
ISO
GO:0007050
cell cycle arrest
ISO
GO:0007050
cell cycle arrest
ISS
GO:0007173
epidermal growth factor receptor signaling pathway
ISO
GO:0007173
epidermal growth factor receptor signaling pathway
ISS
GO:0007179
transforming growth factor beta receptor signaling pathway
ISO
GO:0007179
transforming growth factor beta receptor signaling pathway
ISS
GO:0007183
SMAD protein complex assembly
ISO
GO:0007183
SMAD protein complex assembly
ISS
GO:0007184
SMAD protein import into nucleus
IDA
GO:0007184
SMAD protein import into nucleus
ISO
GO:0007406
negative regulation of neuroblast proliferation
IDA
GO:0007435
salivary gland morphogenesis
IEA
GO:0007435
salivary gland morphogenesis
ISO
GO:0007492
endoderm development
IEA
GO:0007492
endoderm development
ISO
GO:0007565
female pregnancy
IEP
GO:0007568
aging
IEP
GO:0008156
negative regulation of DNA replication
ISO
GO:0008156
negative regulation of DNA replication
ISS
GO:0008219
cell death
IEA
GO:0008219
cell death
ISO
GO:0008283
cell proliferation
ISO
GO:0008284
positive regulation of cell proliferation
ISO
GO:0008284
positive regulation of cell proliferation
ISS
GO:0008285
negative regulation of cell proliferation
ISO
GO:0008285
negative regulation of cell proliferation
ISS
GO:0008354
germ cell migration
IEA
GO:0008354
germ cell migration
ISO
GO:0009314
response to radiation
IEP
GO:0009611
response to wounding
ISO
GO:0009749
response to glucose stimulus
IEP
GO:0009790
embryo development
IEP
GO:0009817
defense response to fungus, incompatible interaction
IDA
GO:0010033
response to organic substance
IDA
GO:0010628
positive regulation of gene expression
ISO
GO:0010628
positive regulation of gene expression
ISS
GO:0010718
positive regulation of epithelial to mesenchymal transition
ISO
GO:0010718
positive regulation of epithelial to mesenchymal transition
ISS
GO:0010763
positive regulation of fibroblast migration
ISO
GO:0010763
positive regulation of fibroblast migration
ISS
GO:0010800
positive regulation of peptidyl-threonine phosphorylation
ISO
GO:0010800
positive regulation of peptidyl-threonine phosphorylation
ISS
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
ISO
GO:0010862
positive regulation of pathway-restricted SMAD protein phosphorylation
ISS
GO:0010936
negative regulation of macrophage cytokine production
IEA
GO:0010936
negative regulation of macrophage cytokine production
ISO
GO:0014070
response to organic cyclic compound
IEP
GO:0016202
regulation of striated muscle tissue development
IEA
GO:0016202
regulation of striated muscle tissue development
ISO
GO:0017015
regulation of transforming growth factor beta receptor signaling pathway
ISO
GO:0017015
regulation of transforming growth factor beta receptor signaling pathway
ISS
GO:0019049
evasion of host defenses by virus
ISO
GO:0019049
evasion of host defenses by virus
ISS
GO:0022408
negative regulation of cell-cell adhesion
ISO
GO:0022408
negative regulation of cell-cell adhesion
ISS
GO:0030217
T cell differentiation
ISO
GO:0030279
negative regulation of ossification
IEA
GO:0030279
negative regulation of ossification
ISO
GO:0030308
negative regulation of cell growth
ISO
GO:0030308
negative regulation of cell growth
ISS
GO:0030324
lung development
TAS
GO:0030501
positive regulation of bone mineralization
IEA
GO:0030501
positive regulation of bone mineralization
ISO
GO:0030879
mammary gland development
IEA
GO:0030879
mammary gland development
ISO
GO:0031065
positive regulation of histone deacetylation
IEA
GO:0031065
positive regulation of histone deacetylation
ISO
GO:0031100
organ regeneration
IMP
GO:0031536
positive regulation of exit from mitosis
IDA
GO:0031575
mitotic cell cycle G1/S transition checkpoint
ISO
GO:0031575
mitotic cell cycle G1/S transition checkpoint
ISS
GO:0032270
positive regulation of cellular protein metabolic process
ISO
GO:0032270
positive regulation of cellular protein metabolic process
ISS
GO:0032355
response to estradiol stimulus
IEP
GO:0032355
response to estradiol stimulus
ISO
GO:0032570
response to progesterone stimulus
ISO
GO:0032570
response to progesterone stimulus
ISS
GO:0032740
positive regulation of interleukin-17 production
ISO
GO:0032740
positive regulation of interleukin-17 production
ISS
GO:0032801
receptor catabolic process
ISO
GO:0032801
receptor catabolic process
ISS
GO:0032943
mononuclear cell proliferation
IEA
GO:0032943
mononuclear cell proliferation
ISO
GO:0032967
positive regulation of collagen biosynthetic process
ISO
GO:0032967
positive regulation of collagen biosynthetic process
ISS
GO:0033138
positive regulation of peptidyl-serine phosphorylation
ISO
GO:0033138
positive regulation of peptidyl-serine phosphorylation
ISS
GO:0033280
response to vitamin D
IEP
GO:0034616
response to laminar fluid shear stress
IEP
GO:0035066
positive regulation of histone acetylation
IEA
GO:0035066
positive regulation of histone acetylation
ISO
GO:0035307
positive regulation of protein dephosphorylation
ISO
GO:0035307
positive regulation of protein dephosphorylation
ISS
GO:0042060
wound healing
IEP
GO:0042060
wound healing
IMP
GO:0042110
T cell activation
ISO
GO:0042127
regulation of cell proliferation
ISO
GO:0042127
regulation of cell proliferation
TAS
GO:0042130
negative regulation of T cell proliferation
IEA
GO:0042130
negative regulation of T cell proliferation
ISO
GO:0042306
regulation of protein import into nucleus
IEA
GO:0042306
regulation of protein import into nucleus
ISO
GO:0042482
positive regulation of odontogenesis
IEA
GO:0042482
positive regulation of odontogenesis
ISO
GO:0042493
response to drug
IEP
GO:0042552
myelination
IMP
GO:0043011
myeloid dendritic cell differentiation
IEA
GO:0043011
myeloid dendritic cell differentiation
ISO
GO:0043029
T cell homeostasis
IEA
GO:0043029
T cell homeostasis
ISO
GO:0043065
positive regulation of apoptosis
IDA
GO:0043065
positive regulation of apoptosis
IMP
GO:0043406
positive regulation of MAP kinase activity
ISO
GO:0043406
positive regulation of MAP kinase activity
ISS
GO:0043536
positive regulation of blood vessel endothelial cell migration
ISO
GO:0043536
positive regulation of blood vessel endothelial cell migration
ISS
GO:0043537
negative regulation of blood vessel endothelial cell migration
ISO
GO:0043537
negative regulation of blood vessel endothelial cell migration
ISS
GO:0043552
positive regulation of phosphatidylinositol 3-kinase activity
ISO
GO:0043552
positive regulation of phosphatidylinositol 3-kinase activity
ISS
GO:0043932
ossification involved in bone remodeling
IEA
GO:0043932
ossification involved in bone remodeling
ISO
GO:0045066
regulatory T cell differentiation
IEA
GO:0045066
regulatory T cell differentiation
ISO
GO:0045216
cell-cell junction organization
ISO
GO:0045216
cell-cell junction organization
ISS
GO:0045599
negative regulation of fat cell differentiation
ISO
GO:0045599
negative regulation of fat cell differentiation
ISS
GO:0045662
negative regulation of myoblast differentiation
ISO
GO:0045662
negative regulation of myoblast differentiation
ISS
GO:0045786
negative regulation of cell cycle
ISO
GO:0045786
negative regulation of cell cycle
ISS
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
ISS
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
ISS
GO:0045930
negative regulation of mitotic cell cycle
ISO
GO:0045930
negative regulation of mitotic cell cycle
ISS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048298
positive regulation of isotype switching to IgA isotypes
IEA
GO:0048298
positive regulation of isotype switching to IgA isotypes
ISO
GO:0048535
lymph node development
IEA
GO:0048535
lymph node development
ISO
GO:0048565
digestive tract development
IEP
GO:0048642
negative regulation of skeletal muscle tissue development
ISO
GO:0048642
negative regulation of skeletal muscle tissue development
ISS
GO:0048839
inner ear development
IEP
GO:0050679
positive regulation of epithelial cell proliferation
IDA
GO:0050680
negative regulation of epithelial cell proliferation
IDA
GO:0050680
negative regulation of epithelial cell proliferation
ISO
GO:0050714
positive regulation of protein secretion
ISO
GO:0050714
positive regulation of protein secretion
ISS
GO:0050765
negative regulation of phagocytosis
IDA
GO:0050777
negative regulation of immune response
IDA
GO:0050868
negative regulation of T cell activation
ISO
GO:0050921
positive regulation of chemotaxis
ISO
GO:0050921
positive regulation of chemotaxis
ISS
GO:0051092
positive regulation of NF-kappaB transcription factor activity
IDA
GO:0051098
regulation of binding
ISO
GO:0051101
regulation of DNA binding
IEA
GO:0051101
regulation of DNA binding
ISO
GO:0051152
positive regulation of smooth muscle cell differentiation
IDA
GO:0051280
negative regulation of release of sequestered calcium ion into cytosol
IDA
GO:0051781
positive regulation of cell division
IEA
GO:0051897
positive regulation of protein kinase B signaling cascade
ISO
GO:0051897
positive regulation of protein kinase B signaling cascade
ISS
GO:0060364
frontal suture morphogenesis
IEP
GO:0060389
pathway-restricted SMAD protein phosphorylation
ISO
GO:0060389
pathway-restricted SMAD protein phosphorylation
ISS
GO:0060391
positive regulation of SMAD protein import into nucleus
IEA
GO:0060391
positive regulation of SMAD protein import into nucleus
ISO
GO:0060744
mammary gland branching involved in thelarche
IEA
GO:0060744
mammary gland branching involved in thelarche
ISO
GO:0060751
branch elongation involved in mammary gland duct branching
IEA
GO:0060751
branch elongation involved in mammary gland duct branching
ISO
GO:0060762
regulation of branching involved in mammary gland duct morphogenesis
IEA
GO:0060762
regulation of branching involved in mammary gland duct morphogenesis
ISO
GO:0070306
lens fiber cell differentiation
IEA
GO:0070306
lens fiber cell differentiation
ISO
GO:0070723
response to cholesterol
ISO
GO:0070723
response to cholesterol
ISS
GO:0071158
positive regulation of cell cycle arrest
IEA
GO:0071158
positive regulation of cell cycle arrest
ISO
GO:0071363
cellular response to growth factor stimulus
IEA
GO:0071363
cellular response to growth factor stimulus
ISO
GO:0071549
cellular response to dexamethasone stimulus
IDA
GO:0090190
positive regulation of branching involved in ureteric bud morphogenesis
IMP
cellular_component
GO:0005576
extracellular region
IEA
GO:0005578
proteinaceous extracellular matrix
IEA
GO:0005578
proteinaceous extracellular matrix
ISO
GO:0005615
extracellular space
IDA
GO:0005615
extracellular space
ISO
GO:0005634
nucleus
ISO
GO:0005634
nucleus
ISS
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
ISO
GO:0005796
Golgi lumen
IEA
GO:0009986
cell surface
IDA
GO:0030141
stored secretory granule
IDA
GO:0030424
axon
IDA
GO:0031012
extracellular matrix
ISO
GO:0043025
neuronal cell body
IDA
molecular_function
GO:0005114
type II transforming growth factor beta receptor binding
ISO
GO:0005114
type II transforming growth factor beta receptor binding
ISS
GO:0005160
transforming growth factor beta receptor binding
IC
GO:0005160
transforming growth factor beta receptor binding
TAS
GO:0008083
growth factor activity
IEA
GO:0042803
protein homodimerization activity
IDA
GO:0046982
protein heterodimerization activity
IDA
GO:0047485
protein N-terminus binding
IMP
Protein-protein interaction details for Tgfb1 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available