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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Shank3 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000165
MAPKKK cascade
ISO
GO:0001838
embryonic epithelial tube formation
IEA
GO:0001838
embryonic epithelial tube formation
ISO
GO:0007416
synapse assembly
ISO
GO:0021773
striatal medium spiny neuron differentiation
ISO
GO:0021773
striatal medium spiny neuron differentiation
ISS
GO:0035176
social behavior
ISO
GO:0035176
social behavior
ISS
GO:0035641
locomotory exploration behavior
ISO
GO:0035641
locomotory exploration behavior
ISS
GO:0045794
negative regulation of cell volume
ISO
GO:0045794
negative regulation of cell volume
ISS
GO:0048170
positive regulation of long-term neuronal synaptic plasticity
ISS
GO:0048854
brain morphogenesis
ISO
GO:0048854
brain morphogenesis
ISS
GO:0051259
protein oligomerization
IDA
GO:0051835
positive regulation of synapse structural plasticity
ISS
GO:0051968
positive regulation of synaptic transmission, glutamatergic
ISO
GO:0051968
positive regulation of synaptic transmission, glutamatergic
ISS
GO:0060997
dendritic spine morphogenesis
ISO
GO:0060997
dendritic spine morphogenesis
ISS
GO:0071625
vocalization behavior
ISS
GO:0097107
postsynaptic density assembly
ISO
GO:0097107
postsynaptic density assembly
ISS
GO:2000463
positive regulation of excitatory postsynaptic membrane potential
ISO
GO:2000463
positive regulation of excitatory postsynaptic membrane potential
ISS
GO:2000821
regulation of grooming behavior
ISO
GO:2000822
regulation of behavioral fear response
ISO
GO:2000822
regulation of behavioral fear response
ISS
GO:2000969
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
ISO
GO:2000969
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
ISS
cellular_component
GO:0005737
cytoplasm
IEA
GO:0005886
plasma membrane
ISO
GO:0005886
plasma membrane
ISS
GO:0014069
postsynaptic density
IDA
GO:0030054
cell junction
IEA
GO:0044309
neuron spine
ISO
GO:0044309
neuron spine
ISS
GO:0045202
synapse
IDA
GO:0045211
postsynaptic membrane
IEA
molecular_function
GO:0005515
protein binding
IPI
GO:0008022
protein C-terminus binding
IPI
GO:0008022
protein C-terminus binding
ISO
GO:0008270
zinc ion binding
IDA
GO:0017124
SH3 domain binding
IPI
GO:0030160
GKAP/Homer scaffold activity
IDA
GO:0035255
ionotropic glutamate receptor binding
ISO
GO:0035255
ionotropic glutamate receptor binding
ISS
GO:0043621
protein self-association
IDA
GO:0097110
scaffold protein binding
IPI
GO:0097110
scaffold protein binding
ISO
Protein-protein interaction details for Shank3 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Interacting protein
Experiment
Type
PubMed ID
Homer1
Two-hybrid
physical
10433269
Homer1
Reconstituted Complex
physical
10433269
Dlgap3
Two-hybrid
physical
10433269
Dlgap3
Reconstituted Complex
physical
10433269
Dlgap3
Reconstituted Complex
physical
10433269
Grm5
Reconstituted Complex
physical
10433269
Dlgap1
Two-hybrid
physical
10433268