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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CCND1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000079 regulation of cyclin-dependent protein kinase activity IEA GO:0000080 G1 phase of mitotic cell cycle TAS GO:0000082 G1/S transition of mitotic cell cycle IDA GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0000320 re-entry into mitotic cell cycle IEA GO:0001889 liver development IEA GO:0001934 positive regulation of protein phosphorylation IDA GO:0006974 response to DNA damage stimulus IDA GO:0007595 lactation IEA GO:0008284 positive regulation of cell proliferation IEA GO:0010039 response to iron ion IEA GO:0010165 response to X-ray IEA GO:0010243 response to organic nitrogen IEA GO:0014070 response to organic cyclic compound IEA GO:0030178 negative regulation of Wnt receptor signaling pathway IEA GO:0030857 negative regulation of epithelial cell differentiation IEA GO:0030968 endoplasmic reticulum unfolded protein response IEA GO:0031100 organ regeneration IEA GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint IDA GO:0032026 response to magnesium ion IEA GO:0033197 response to vitamin E IEA GO:0033327 Leydig cell differentiation IEA GO:0033601 positive regulation of mammary gland epithelial cell proliferation IEA GO:0042493 response to drug IEP GO:0043627 response to estrogen stimulus IEA GO:0045444 fat cell differentiation IEA GO:0045471 response to ethanol IEA GO:0045737 positive regulation of cyclin-dependent protein kinase activity IDA GO:0051301 cell division IEA GO:0051412 response to corticosterone stimulus IEA GO:0051592 response to calcium ion IEA GO:0060070 canonical Wnt receptor signaling pathway IEA GO:0060749 mammary gland alveolus development IEA GO:0070141 response to UV-A IDA GO:0071310 cellular response to organic substance IEA cellular_component GO:0000307 cyclin-dependent protein kinase holoenzyme complex IDA GO:0005622 intracellular IDA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0016020 membrane IEA molecular_function GO:0004672 protein kinase activity IEA GO:0005515 protein binding IPI GO:0016538 cyclin-dependent protein kinase regulator activity IEA GO:0019899 enzyme binding IPI GO:0019901 protein kinase binding IEA GO:0019901 protein kinase binding IPI

Protein-protein interaction details for CCND1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID AR Affinity Capture-Western physical 15558026 AR Reconstituted Complex physical 15558026 HDAC3 Affinity Capture-Western physical 15558026 AKAP8 Affinity Capture-Western physical 14641107 THRB Reconstituted Complex physical 12048199 THRB Affinity Capture-Western physical 12048199 HDAC3 Affinity Capture-Western physical 12048199 THRA Affinity Capture-Western physical 12048199 KAT2B Affinity Capture-Western physical 10318892 NEUROD1 Phenotypic Suppression genetic 11788592 NEUROD1 Affinity Capture-Western physical 11788592 EP300 Reconstituted Complex physical 11788592 CDK4 Reconstituted Complex physical 10580009 CDK6 Reconstituted Complex physical 10580009 CDKN2A Reconstituted Complex physical 10580009 CDK4 Affinity Capture-Western physical 10580009 TAF1 Affinity Capture-Western physical 9926939 TAF1 Affinity Capture-Western physical 9926939 TAF1 Reconstituted Complex physical 9926939 CDK4 Affinity Capture-Western physical 8259215 CCNDBP1 Affinity Capture-Western physical 10801854 CCNDBP1 Reconstituted Complex physical 10801854 TAF1 Reconstituted Complex physical 11126356 RB1 Reconstituted Complex physical 11126356 RB1 Phenotypic Suppression genetic 11126356 HERC5 Reconstituted Complex physical 10581175 CDKN1C Reconstituted Complex physical 10764802 RB1 Affinity Capture-Western physical 8490963 CDK4 Affinity Capture-Western physical 11360184 CDK6 Affinity Capture-Western physical 11360184 CDKN1B Reconstituted Complex physical 11360184 ESR1 Reconstituted Complex physical 9039267 ESR1 Two-hybrid physical 9039267 ESR1 Affinity Capture-Western physical 9039267 RBX1 Affinity Capture-Western physical 11311237 STAT3 Affinity Capture-Western physical 11279133 TSC2 Affinity Capture-Western physical 16357142 NPDC1 Reconstituted Complex physical 11042687 NCOA3 Affinity Capture-Western physical 9832502 NCOA1 Affinity Capture-Western physical 9832502 NCOA1 Reconstituted Complex physical 9832502 RFC1 Affinity Capture-Western physical 10353443 AR Affinity Capture-Western physical 10344732 PCNA Reconstituted Complex physical 7908906 BRCA1 Reconstituted Complex physical 9244350 XPO1 Reconstituted Complex physical 12529437 CDK4 Affinity Capture-Western physical 9837900 CDKN1A Reconstituted Complex physical 8657154 CDK4 Affinity Capture-Western physical 10908655 CDK4 Reconstituted Complex physical 9228064 PCNA Affinity Capture-Western physical 8101826 CDKN1B Affinity Capture-Western physical 15695403 CDKN1A Affinity Capture-Western physical 15695403 INSM1 Reconstituted Complex physical 16569215 INSM1 Affinity Capture-Western physical 16569215 INSM1 Affinity Capture-Western physical 16569215 INSM1 Reconstituted Complex physical 16569215 INSM1 Two-hybrid physical 16569215 HSPA8 Affinity Capture-Western physical 18537972 HSPA8 Affinity Capture-Western physical 18537972 CDK4 Affinity Capture-Western physical 18537972 CDK4 Affinity Capture-Western physical 18537972 CDKN1A Reconstituted Complex physical 16082198 ESR1 Affinity Capture-Western physical 16061635 ESR1 Reconstituted Complex physical 16061635 HDAC1 Affinity Capture-Western physical 15713663 HDAC2 Affinity Capture-Western physical 15713663 HDAC3 Affinity Capture-Western physical 15713663 HDAC1 Co-localization physical 15713663 HDAC3 Co-localization physical 15713663 STAT3 Reconstituted Complex physical 15659654 STAT3 Affinity Capture-Western physical 15659654 RB1 Reconstituted Complex physical 11593423 RB1 Affinity Capture-Western physical 15485920 RB1 Biochemical Activity physical 15485920 HDAC1 Affinity Capture-Western physical 20484017 HDAC3 Affinity Capture-Western physical 20484017 MAPK11 Biochemical Activity physical 10952989 UBC Affinity Capture-Western physical 10766840 BRCA1 Biochemical Activity physical 17334399 CDK4 Affinity Capture-Western physical 9372967 WDR77 Affinity Capture-Western physical 20951943 PRMT5 Affinity Capture-Western physical 20951943 UBC Affinity Capture-Western physical 17205132 MAPK1 Affinity Capture-Western physical 17205132 CDK4 Affinity Capture-Western physical 17205132 SKP1 Affinity Capture-Western physical 17205132 CUL1 Affinity Capture-Western physical 17205132 CUL7 Affinity Capture-Western physical 17205132 FBXW8 Biochemical Activity physical 17205132 FBXW8 Affinity Capture-Western physical 17205132 CRYAB Affinity Capture-MS physical 17081987 CDK4 Affinity Capture-MS physical 17081987 CDKN1A Affinity Capture-MS physical 17081987 CRYAB Affinity Capture-Western physical 17081987 FBXO4 Affinity Capture-Western physical 17081987 FBXO4 Affinity Capture-Western physical 17081987 SKP1 Affinity Capture-Western physical 17081987 CUL1 Affinity Capture-Western physical 17081987 CDK4 Affinity Capture-Western physical 16613857 CRYAB Biochemical Activity physical 17081987 FBXO4 Biochemical Activity physical 17081987 FBXO31 Affinity Capture-Western physical 19412162 FBXO31 Affinity Capture-Western physical 19412162 UBC Affinity Capture-Western physical 19412162 FBXO31 Biochemical Activity physical 19412162 CDK4 Affinity Capture-Western physical 20837141 ARID4A Biochemical Activity physical 21148318 CDKN1A Affinity Capture-Western physical 17556661 CDKN1A Affinity Capture-Western physical 17556661 USP2 Biochemical Activity physical 19917254 UBC Affinity Capture-Western physical 19917254 USP2 Affinity Capture-Western physical 19917254 USP2 Affinity Capture-Western physical 19917254 USP2 Reconstituted Complex physical 19917254 UHRF2 Far Western physical 21952639 UHRF2 Affinity Capture-Western physical 21952639 UHRF2 Affinity Capture-Western physical 21952639 UHRF2 Reconstituted Complex physical 21952639 UHRF2 Biochemical Activity physical 21952639 UBC Affinity Capture-Western physical 21952639 UBC Reconstituted Complex physical 19475398 FBXO5 Biochemical Activity physical 19475398 SP1 Affinity Capture-Western physical 10850422 FBXO4 Biochemical Activity physical 21242966 UBC Affinity Capture-Western physical 21242966 UBC Affinity Capture-MS physical 21987572