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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RPS6KB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IMP GO:0003009 skeletal muscle contraction IEA GO:0006468 protein phosphorylation IDA GO:0006468 protein phosphorylation TAS GO:0007049 cell cycle IEA GO:0007165 signal transduction IEA GO:0007281 germ cell development IEA GO:0007568 aging IEA GO:0007584 response to nutrient IEA GO:0007616 long-term memory IEA GO:0008286 insulin receptor signaling pathway TAS GO:0009408 response to heat IEA GO:0009611 response to wounding IEA GO:0009612 response to mechanical stimulus IEA GO:0009636 response to toxin IEA GO:0009749 response to glucose stimulus IEA GO:0014070 response to organic cyclic compound IEA GO:0014732 skeletal muscle atrophy IEA GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation IEA GO:0014911 positive regulation of smooth muscle cell migration IEA GO:0016477 cell migration IEA GO:0031929 TOR signaling cascade IDA GO:0032496 response to lipopolysaccharide IEA GO:0032868 response to insulin stimulus IEA GO:0032870 cellular response to hormone stimulus IEA GO:0033574 response to testosterone stimulus IEA GO:0033762 response to glucagon stimulus IEA GO:0034612 response to tumor necrosis factor IEA GO:0042493 response to drug IEA GO:0043066 negative regulation of apoptosis IEA GO:0043066 negative regulation of apoptosis IMP GO:0043201 response to leucine IEA GO:0045471 response to ethanol IEA GO:0045727 positive regulation of translation IMP GO:0045931 positive regulation of mitotic cell cycle IMP GO:0045948 positive regulation of translational initiation IMP GO:0046324 regulation of glucose import IEA GO:0046627 negative regulation of insulin receptor signaling pathway IEA GO:0048015 phosphatidylinositol-mediated signaling TAS GO:0048633 positive regulation of skeletal muscle tissue growth IEA GO:0048661 positive regulation of smooth muscle cell proliferation IEA GO:0051384 response to glucocorticoid stimulus IEA cellular_component GO:0005625 soluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005739 mitochondrion IDA GO:0005739 mitochondrion IEA GO:0005741 mitochondrial outer membrane IEA GO:0005829 cytosol TAS GO:0005840 ribosome IEA GO:0009986 cell surface IEA GO:0016020 membrane IEA GO:0019717 synaptosome IEA GO:0030054 cell junction IEA GO:0045202 synapse IEA GO:0048471 perinuclear region of cytoplasm IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IDA GO:0004672 protein kinase activity TAS GO:0004674 protein serine/threonine kinase activity IEA GO:0004711 ribosomal protein S6 kinase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0042277 peptide binding IEA

Protein-protein interaction details for RPS6KB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRAF4 Affinity Capture-Western physical 12801526 AKT1 Co-purification physical 15149849 CSNK2B Reconstituted Complex physical 16895915 CSNK2B Reconstituted Complex physical 16895915 CSNK2B Affinity Capture-Western physical 16895915 MTOR Affinity Capture-Western physical 15899889 MTOR Affinity Capture-Western physical 15905173 MTOR Reconstituted Complex physical 15905173 MTOR Affinity Capture-Western physical 12150926 GDI2P1 Reconstituted Complex physical 15249583 GDI2P1 Biochemical Activity physical 16914728 PPP2R2A Affinity Capture-Western physical 10200280 ACTA1 Reconstituted Complex physical 15149849 BTK Biochemical Activity physical 16640565 CSNK2A1 Reconstituted Complex physical 16895915 MTOR Reconstituted Complex physical 10567431 MTOR Reconstituted Complex physical 15854902 MTOR Reconstituted Complex physical 15896331 MTOR Reconstituted Complex physical 15809305 MTOR Reconstituted Complex physical 11914378 MTOR Affinity Capture-Western physical 12150925 MTOR Affinity Capture-Western physical 14679009 MTOR Biochemical Activity physical 16922504 MTOR Affinity Capture-Western physical 10971657 MTOR Reconstituted Complex physical 9465032 MTOR Reconstituted Complex physical 12604610 MTOR Biochemical Activity physical 16183647 LYN Biochemical Activity physical 16640565 PDK1 Reconstituted Complex physical 11733037 PPP2R2A Affinity Capture-Western physical 16899564 PRKCZ Affinity Capture-Western physical 16931574 SRC Biochemical Activity physical 16640565 SYK Biochemical Activity physical 16640565 EIF3B Affinity Capture-Western physical 16286006 EIF3C Affinity Capture-Western physical 16286006 RPTOR Reconstituted Complex physical 15809305 RPTOR Affinity Capture-Western physical 16837165 COASY Affinity Capture-Western physical 15589845 COASY Reconstituted Complex physical 15589845 POLDIP3 Affinity Capture-Western physical 15341740 RICTOR Reconstituted Complex physical 15809305 TERT Affinity Capture-Western physical 15843522 XPO1 Affinity Capture-Western physical 16895915 EIF3B Affinity Capture-Western physical 16286006 EIF3F Affinity Capture-MS physical 16286006 EEF2K Reconstituted Complex physical 11500364 RPTOR Affinity Capture-Western physical 12150926 RPTOR Affinity Capture-Western physical 12604610 POLDIP3 Two-hybrid physical 15341740 POLDIP3 Affinity Capture-Western physical 15341740 POLDIP3 Biochemical Activity physical 15341740 RBX1 Reconstituted Complex physical 18279656 RBX1 Affinity Capture-Western physical 18279656 UBC Affinity Capture-Western physical 18279656 UBC Affinity Capture-Western physical 18279656 MDM2 Affinity Capture-Western physical 20657550 MDM2 Affinity Capture-Western physical 20657550 EP300 Affinity Capture-Western physical 19961954 KAT2B Affinity Capture-Western physical 19961954 EP300 Affinity Capture-Western physical 19961954 KAT2B Affinity Capture-Western physical 19961954 EP300 Biochemical Activity physical 19961954 KAT2B Biochemical Activity physical 19961954 DPPA4 Two-hybrid physical 21900206 CLEC3B Two-hybrid physical 21900206 MXD1 Biochemical Activity physical 18451027