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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RYR1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIDA
GO:0006811ion transportIEA
GO:0006816calcium ion transportIEA
GO:0006816calcium ion transportISS
GO:0006936muscle contractionIEA
GO:0031000response to caffeineISS
GO:0051209release of sequestered calcium ion into cytosolIEA
GO:0051209release of sequestered calcium ion into cytosolISS
GO:0051480cytosolic calcium ion homeostasisISS
GO:0055085transmembrane transportIEA
cellular_component
GO:0005624membrane fractionIEA
GO:0005737cytoplasmIDA
GO:0005790smooth endoplasmic reticulumTAS
GO:0005829cytosolISS
GO:0005886plasma membraneIDA
GO:0005887integral to plasma membraneTAS
GO:0005938cell cortexIDA
GO:0014701junctional sarcoplasmic reticulum membraneTAS
GO:0014802terminal cisternaISS
GO:0016529sarcoplasmic reticulumISS
GO:0030314junctional membrane complexIEA
GO:0030315T-tubuleIEA
GO:0031674I bandIDA
GO:0033017sarcoplasmic reticulum membraneIEA
molecular_function
GO:0004872receptor activityIEA
GO:0005216ion channel activityIEA
GO:0005219ryanodine-sensitive calcium-release channel activityISS
GO:0005219ryanodine-sensitive calcium-release channel activityTAS
GO:0005245voltage-gated calcium channel activityIEA
GO:0005509calcium ion bindingIEA
GO:0005516calmodulin bindingISS
GO:0015278calcium-release channel activityTAS

Protein-protein interaction details for RYR1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TRDNReconstituted Complexphysical14638677
HOMER1Reconstituted Complexphysical12810060
FKBP1AAffinity Capture-Westernphysical12704193
RYR2Affinity Capture-Westernphysical12213830
FKBP1AReconstituted Complexphysical11171121
FKBP1AAffinity Capture-Westernphysical11171121
TRDNReconstituted Complexphysical9890886
FKBP1AReconstituted Complexphysical11279144
TRDNReconstituted Complexphysical7721813
S100A1Reconstituted Complexphysical9298970
HOMER1Reconstituted Complexphysical12223488
HOMER1Affinity Capture-Westernphysical12223488
HOMER2Reconstituted Complexphysical12223488
HOMER2Affinity Capture-Westernphysical12223488
HOMER3Affinity Capture-Westernphysical12223488
HOMER3Reconstituted Complexphysical12223488
TRDNProtein-peptidephysical10212196
TRDNFar Westernphysical10212196