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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RYR2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001666 response to hypoxia ISS GO:0005513 detection of calcium ion IDA GO:0006811 ion transport IEA GO:0006816 calcium ion transport IDA GO:0006874 cellular calcium ion homeostasis IEA GO:0008627 induction of apoptosis by ionic changes IDA GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IC GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion ISS GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISS GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum TAS GO:0031000 response to caffeine IDA GO:0051209 release of sequestered calcium ion into cytosol ISS GO:0051480 cytosolic calcium ion homeostasis ISS GO:0051775 response to redox state IDA GO:0055085 transmembrane transport IEA GO:0060048 cardiac muscle contraction IMP GO:0060402 calcium ion transport into cytosol TAS GO:0070296 sarcoplasmic reticulum calcium ion transport TAS cellular_component GO:0001950 plasma membrane enriched fraction ISS GO:0005829 cytosol ISS GO:0005886 plasma membrane ISS GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0016529 sarcoplasmic reticulum IDA GO:0033017 sarcoplasmic reticulum membrane TAS GO:0034704 calcium channel complex IDA molecular_function GO:0004872 receptor activity IEA GO:0005216 ion channel activity IEA GO:0005219 ryanodine-sensitive calcium-release channel activity IDA GO:0005219 ryanodine-sensitive calcium-release channel activity IEA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0005516 calmodulin binding IMP GO:0005516 calmodulin binding ISS GO:0015278 calcium-release channel activity IDA GO:0034236 protein kinase A catalytic subunit binding IDA GO:0034237 protein kinase A regulatory subunit binding IDA GO:0042802 identical protein binding IPI GO:0043924 suramin binding IMP

Protein-protein interaction details for RYR2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HOMER1 Reconstituted Complex physical 12887973 PRKACA Biochemical Activity physical 10830164 PRKACG Biochemical Activity physical 10830164 PRKACB Biochemical Activity physical 10830164 RYR2 Co-fractionation physical 10830164 PRKACB Co-fractionation physical 10830164 PRKACG Co-fractionation physical 10830164 PRKAR2A Co-fractionation physical 10830164 PRKAR2B Co-fractionation physical 10830164 PPP1CA Co-fractionation physical 10830164 PPP1CB Co-fractionation physical 10830164 PPP1CC Co-fractionation physical 10830164 AKAP6 Co-fractionation physical 10830164 PRKACA Co-fractionation physical 10830164 RYR3 Affinity Capture-Western physical 12213830 RYR3 Affinity Capture-Western physical 12213830 RYR1 Affinity Capture-Western physical 12213830 SRI Affinity Capture-Western physical 7592856 SRI Affinity Capture-Western physical 7592856 CACNA1C Reconstituted Complex physical 11576544 FKBP1B Reconstituted Complex physical 12446682 AKAP6 Reconstituted Complex physical 11352932 TERF1 Affinity Capture-MS physical 20811636 TERF2 Affinity Capture-MS physical 20811636 UBC Reconstituted Complex physical 19850743