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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SCNN1A (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006811ion transportIEA
GO:0006814sodium ion transportTAS
GO:0007588excretionTAS
GO:0050896response to stimulusIEA
GO:0050909sensory perception of tasteIEA
cellular_component
GO:0005624membrane fractionIEA
GO:0005886plasma membraneIEA
GO:0009897external side of plasma membraneIEA
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0016324apical plasma membraneIEA
GO:0030864cortical actin cytoskeletonIEA
molecular_function
GO:0003779actin bindingIEA
GO:0005216ion channel activityIEA
GO:0005272sodium channel activityIEA
GO:0005515protein bindingIPI
GO:0015280ligand-gated sodium channel activityIEA
GO:0050699WW domain bindingIEA
GO:0050699WW domain bindingIPI

Protein-protein interaction details for SCNN1A (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
STX1AAffinity Capture-Westernphysical14996668
NEDD4Reconstituted Complexphysical10642508
WWP2Reconstituted Complexphysical12167593
NEDD4Reconstituted Complexphysical12167593
NEDD4Far Westernphysical11244092
NEDD4LFar Westernphysical11244092
HECW1Far Westernphysical11244092
ITCHFar Westernphysical11244092
NEDD4LTwo-hybridphysical14556380
TSG101Two-hybridphysical14556380
WWP1Two-hybridphysical14556380
UBE2ITwo-hybridphysical14556380
UBCAffinity Capture-Westernphysical18632802
USP10Affinity Capture-Westernphysical18632802
SNX3Affinity Capture-Westernphysical18632802
UBCAffinity Capture-Westernphysical18322022
NEDD4LAffinity Capture-Westernphysical17502380
UBCAffinity Capture-Westernphysical17381423
UBCAffinity Capture-Westernphysical9351815
EPN1Affinity Capture-Westernphysical16574660
UBCAffinity Capture-Westernphysical16574660
UBCAffinity Capture-Westernphysical16574660
AP1M2Affinity Capture-Westernphysical16574660
EPN1Reconstituted Complexphysical16574660
USP2Affinity Capture-Westernphysical21478478
UBCAffinity Capture-Westernphysical21084303
HGSAffinity Capture-Westernphysical20675381
HGSAffinity Capture-Westernphysical20675381
UBCAffinity Capture-Westernphysical20675381