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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CX3CL1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIEA
GO:0006935chemotaxisIEA
GO:0006952defense responseTAS
GO:0006955immune responseTAS
GO:0010759positive regulation of macrophage chemotaxisIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030168platelet activationIEA
GO:0030335positive regulation of cell migrationIEA
GO:0030593neutrophil chemotaxisIEA
GO:0030595leukocyte chemotaxisTAS
GO:0032914positive regulation of transforming growth factor beta1 productionIEA
GO:0043066negative regulation of apoptosisIEA
GO:0045766positive regulation of angiogenesisIEA
GO:0045785positive regulation of cell adhesionIEA
GO:0045906negative regulation of vasoconstrictionIEA
GO:0048247lymphocyte chemotaxisIEA
GO:0048661positive regulation of smooth muscle cell proliferationIEA
GO:0050710negative regulation of cytokine secretionIEA
GO:0050729positive regulation of inflammatory responseIEP
GO:0050902leukocyte adhesive activationTAS
GO:0051041positive regulation of calcium-independent cell-cell adhesionIDA
GO:0060055angiogenesis involved in wound healingIEA
GO:0060080regulation of inhibitory postsynaptic membrane potentialIEA
cellular_component
GO:0005576extracellular regionIDA
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionIEA
GO:0005737cytoplasmIEA
GO:0005886plasma membraneTAS
GO:0009986cell surfaceIDA
GO:0016021integral to membraneIDA
GO:0042995cell projectionIEA
GO:0048471perinuclear region of cytoplasmIEA
molecular_function
GO:0005102receptor bindingTAS
GO:0005515protein bindingIPI
GO:0008009chemokine activityTAS

Protein-protein interaction details for CX3CL1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CX3CR1Co-crystal Structurephysical9931005
CX3CL1Co-crystal Structurephysical10770945