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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CXCL12 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001569patterning of blood vesselsIEA
GO:0001666response to hypoxiaIEA
GO:0001667ameboidal cell migrationIEA
GO:0001764neuron migrationIEA
GO:0001938positive regulation of endothelial cell proliferationIEA
GO:0006874cellular calcium ion homeostasisTAS
GO:0006935chemotaxisIEA
GO:0006955immune responseIEA
GO:0007155cell adhesionTAS
GO:0007165signal transductionTAS
GO:0007186G-protein coupled receptor protein signaling pathwayTAS
GO:0007281germ cell developmentIEA
GO:0007420brain developmentIEA
GO:0008015blood circulationTAS
GO:0008045motor axon guidanceIEA
GO:0008064regulation of actin polymerization or depolymerizationTAS
GO:0008284positive regulation of cell proliferationIEA
GO:0008344adult locomotory behaviorIEA
GO:0008354germ cell migrationIEA
GO:0009314response to radiationIEA
GO:0009408response to heatIEA
GO:0009612response to mechanical stimulusIEA
GO:0009615response to virusTAS
GO:0022029telencephalon cell migrationIEA
GO:0030335positive regulation of cell migrationIEA
GO:0031100organ regenerationIEA
GO:0033603positive regulation of dopamine secretionIEA
GO:0042098T cell proliferationIEA
GO:0043066negative regulation of apoptosisIDA
GO:0043434response to peptide hormone stimulusIEA
GO:0045666positive regulation of neuron differentiationIEA
GO:0048842positive regulation of axon extension involved in axon guidanceIEA
GO:0050930induction of positive chemotaxisIEA
GO:0051929positive regulation of calcium ion transport via voltage-gated calcium channel activityIEA
GO:0070098chemokine-mediated signaling pathwayIDA
GO:0090026positive regulation of monocyte chemotaxisIDA
GO:2000107negative regulation of leukocyte apoptosisIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0005886plasma membraneIEA
GO:0009897external side of plasma membraneIEA
molecular_function
GO:0004871signal transducer activityTAS
GO:0005102receptor bindingTAS
GO:0008009chemokine activityIEA
GO:0008083growth factor activityIEA
GO:0045236CXCR chemokine receptor bindingIDA

Protein-protein interaction details for CXCL12 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
FN1Reconstituted Complexphysical11023498
CXCL12Co-crystal Structurephysical10954912
PF4Reconstituted Complexphysical10233851
VCANReconstituted Complexphysical11083865