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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SKIL (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0001825 blastocyst formation IEA GO:0002260 lymphocyte homeostasis IEA GO:0007050 cell cycle arrest IEA GO:0007050 cell cycle arrest ISS GO:0007519 skeletal muscle tissue development IDA GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA GO:0042981 regulation of apoptosis IBA GO:0042981 regulation of apoptosis IEA GO:0042981 regulation of apoptosis ISS GO:0045596 negative regulation of cell differentiation IEA GO:0045596 negative regulation of cell differentiation ISS GO:0046677 response to antibiotic IEP GO:0050772 positive regulation of axonogenesis IMP GO:0070207 protein homotrimerization IDA GO:0070208 protein heterotrimerization IDA GO:0070306 lens fiber cell differentiation IEA GO:0070848 response to growth factor stimulus IDA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0016605 PML body IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IDA GO:0003682 chromatin binding IEA GO:0003682 chromatin binding ISS GO:0003714 transcription corepressor activity IDA GO:0005515 protein binding IPI GO:0019904 protein domain specific binding IPI GO:0032403 protein complex binding IDA GO:0046332 SMAD binding IPI

Protein-protein interaction details for SKIL (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SMAD3 Affinity Capture-Western physical 11691834 SMAD2 Affinity Capture-Western physical 11691834 SMAD3 Affinity Capture-Western physical 11691834 FZR1 Affinity Capture-Western physical 11691834 SMAD4 Affinity Capture-MS physical 10531062 SMAD4 Affinity Capture-Western physical 10531062 SMAD2 Affinity Capture-Western physical 10531062 SMAD3 Affinity Capture-Western physical 10531062 SMURF2 Affinity Capture-Western physical 11389444 SKIL Reconstituted Complex physical 9927733 SKI Reconstituted Complex physical 9927733 SKI Affinity Capture-Western physical 9927733 SNW1 Phenotypic Suppression genetic 11278756 RNF111 Affinity Capture-Western physical 17591695 RNF111 Biochemical Activity physical 17591695 NEDD4 Affinity Capture-Western physical 15496141 WWP1 Affinity Capture-Western physical 15221015 UBC Affinity Capture-Western physical 15221015 ING2 Affinity Capture-Western physical 18334480 SMAD3 Reconstituted Complex physical 11306568 NCOR1 Two-hybrid physical 10049357 NCOR2 Two-hybrid physical 10049357 NCOR1 Affinity Capture-Western physical 10049357 NCOR2 Affinity Capture-Western physical 10049357 NCOR1 Reconstituted Complex physical 10049357 NCOR2 Reconstituted Complex physical 10049357 SIN3A Affinity Capture-Western physical 10049357 NCOR1 Affinity Capture-Western physical 10049357 NCOR2 Affinity Capture-Western physical 10049357 HDAC1 Affinity Capture-Western physical 10049357 NCOR1 Co-localization physical 10049357 NCOR2 Co-localization physical 10049357 RB1 Affinity Capture-Western physical 9988677 SKI Affinity Capture-Western physical 16959829 SMAD2 Affinity Capture-Western physical 16959829 SMAD3 Affinity Capture-Western physical 16959829 TGFBR1 Affinity Capture-Western physical 20959473 SMAD3 Affinity Capture-Western physical 12426322 SMAD1 Affinity Capture-Western physical 12426322 SMAD2 Affinity Capture-Western physical 12426322