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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PINK1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000422 mitochondrion degradation IMP GO:0006468 protein phosphorylation IDA GO:0006950 response to stress IDA GO:0007243 intracellular protein kinase cascade IDA GO:0008219 cell death IEA GO:0018105 peptidyl-serine phosphorylation IDA GO:0031396 regulation of protein ubiquitination IDA GO:0032226 positive regulation of synaptic transmission, dopaminergic IEA GO:0033603 positive regulation of dopamine secretion IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IDA GO:0043254 regulation of protein complex assembly IDA GO:0090200 positive regulation of release of cytochrome c from mitochondria IMP cellular_component GO:0005737 cytoplasm IEA GO:0005739 mitochondrion IDA GO:0005741 mitochondrial outer membrane IEA GO:0005829 cytosol IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0000287 magnesium ion binding IDA GO:0004674 protein serine/threonine kinase activity IDA GO:0005524 ATP binding IDA GO:0010857 calcium-dependent protein kinase activity IDA GO:0016301 kinase activity IDA GO:0031625 ubiquitin protein ligase binding IPI GO:0055131 C3HC4-type RING finger domain binding IPI

Protein-protein interaction details for PINK1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PARK2 Reconstituted Complex physical 19358826 PARK2 Affinity Capture-Western physical 19358826 PTEN Affinity Capture-MS physical 15717329 UBC Affinity Capture-MS physical 21987572