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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BMPR2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001707 mesoderm formation ISS GO:0001938 positive regulation of endothelial cell proliferation IMP GO:0003085 negative regulation of systemic arterial blood pressure IMP GO:0006366 transcription from RNA polymerase II promoter IMP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IDA GO:0007420 brain development IEA GO:0009267 cellular response to starvation IEP GO:0009952 anterior/posterior pattern specification ISS GO:0010595 positive regulation of endothelial cell migration IMP GO:0010634 positive regulation of epithelial cell migration IDA GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IMP GO:0014916 regulation of lung blood pressure IMP GO:0014916 regulation of lung blood pressure ISS GO:0030308 negative regulation of cell growth IDA GO:0030501 positive regulation of bone mineralization IMP GO:0030509 BMP signaling pathway IDA GO:0030509 BMP signaling pathway IMP GO:0030509 BMP signaling pathway ISS GO:0030509 BMP signaling pathway TAS GO:0030513 positive regulation of BMP signaling pathway IMP GO:0042127 regulation of cell proliferation IMP GO:0045669 positive regulation of osteoblast differentiation IMP GO:0045906 negative regulation of vasoconstriction ISS GO:0048010 vascular endothelial growth factor receptor signaling pathway ISS GO:0048286 lung alveolus development ISS GO:0060041 retina development in camera-type eye IEA cellular_component GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005901 caveola IMP GO:0009925 basal plasma membrane IEA GO:0009986 cell surface IEA GO:0016324 apical plasma membrane IEA GO:0030425 dendrite IEA GO:0043025 neuronal cell body IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004675 transmembrane receptor protein serine/threonine kinase activity TAS GO:0004872 receptor activity IEA GO:0005024 transforming growth factor beta-activated receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016362 activin receptor activity, type II TAS GO:0019838 growth factor binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for BMPR2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LIMK1 Two-hybrid physical 12963706 CES3 Affinity Capture-MS physical 15188402 GCGR Affinity Capture-MS physical 15188402 CRYAB Affinity Capture-MS physical 15188402 FRS3 Affinity Capture-MS physical 15188402 TGFBR1 Two-hybrid physical 7791754 ACVR1B Two-hybrid physical 7791754 TSR1 Two-hybrid physical 7791754 ACVR1 Two-hybrid physical 7791754 ACVR1 Affinity Capture-Western physical 7791754 ACVR1 Two-hybrid physical 7791754 ACVR1 Affinity Capture-Western physical 7791754 BMPR1A Affinity Capture-Western physical 7791754 BMPR1B Affinity Capture-Western physical 7791754 BMP2 Affinity Capture-Western physical 7791754 BMP7 Affinity Capture-Western physical 7791754 BMPR1A Affinity Capture-Western physical 7791754 BMPR1B Affinity Capture-Western physical 7791754 LIMK1 Affinity Capture-Western physical 12963706 GDF5 Reconstituted Complex physical 9525338 GDF6 Reconstituted Complex physical 9525338 BMP4 Affinity Capture-Western physical 7644468 BMP6 Affinity Capture-Western physical 10504300 BMP2 Reconstituted Complex physical 10880444 GDF9 Reconstituted Complex physical 12135884 BMPR1A Affinity Capture-Western physical 10712517 BMPR1B Affinity Capture-Western physical 10712517 BMPR2 Affinity Capture-Western physical 10712517 BMP2 Reconstituted Complex physical 10712517 BMPR1A Co-localization physical 10712517 BMPR1B Co-localization physical 10712517 ACVR1 Two-hybrid physical 7890683 TGFBR1 Two-hybrid physical 7890683 FHL2 Two-hybrid physical 19265191 FHL2 Affinity Capture-Western physical 19265191 XIAP Affinity Capture-Western physical 19782107 MAPK8 Two-hybrid physical 21900206