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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SOD1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity ISS GO:0000303 response to superoxide IDA GO:0001541 ovarian follicle development ISS GO:0001819 positive regulation of cytokine production IDA GO:0001890 placenta development NAS GO:0001895 retina homeostasis ISS GO:0001975 response to amphetamine IEA GO:0002262 myeloid cell homeostasis ISS GO:0002576 platelet degranulation TAS GO:0006302 double-strand break repair ISS GO:0006309 DNA fragmentation involved in apoptotic nuclear change ISS GO:0006749 glutathione metabolic process ISS GO:0006801 superoxide metabolic process ISS GO:0006879 cellular iron ion homeostasis ISS GO:0006916 anti-apoptosis IEA GO:0007283 spermatogenesis ISS GO:0007566 embryo implantation ISS GO:0007566 embryo implantation NAS GO:0007569 cell aging IMP GO:0007596 blood coagulation TAS GO:0007605 sensory perception of sound ISS GO:0007626 locomotory behavior ISS GO:0008217 regulation of blood pressure ISS GO:0008219 cell death IEA GO:0009408 response to heat ISS GO:0010033 response to organic substance IDA GO:0019226 transmission of nerve impulse ISS GO:0019430 removal of superoxide radicals IBA GO:0019430 removal of superoxide radicals ISS GO:0030168 platelet activation TAS GO:0031667 response to nutrient levels IEA GO:0032287 peripheral nervous system myelin maintenance ISS GO:0033081 regulation of T cell differentiation in thymus NAS GO:0040014 regulation of multicellular organism growth ISS GO:0042493 response to drug ISS GO:0042542 response to hydrogen peroxide ISS GO:0042554 superoxide anion generation IEA GO:0043065 positive regulation of apoptosis IC GO:0043085 positive regulation of catalytic activity IDA GO:0043524 negative regulation of neuron apoptosis ISS GO:0045471 response to ethanol ISS GO:0045541 negative regulation of cholesterol biosynthetic process IDA GO:0045859 regulation of protein kinase activity IDA GO:0046620 regulation of organ growth NAS GO:0046688 response to copper ion IEA GO:0046716 muscle cell homeostasis ISS GO:0048538 thymus development NAS GO:0048678 response to axon injury ISS GO:0050665 hydrogen peroxide biosynthetic process IDA GO:0050665 hydrogen peroxide biosynthetic process ISS GO:0051881 regulation of mitochondrial membrane potential IMP GO:0060047 heart contraction IDA GO:0060052 neurofilament cytoskeleton organization ISS GO:0060087 relaxation of vascular smooth muscle ISS GO:0060088 auditory receptor cell stereocilium organization ISS cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IDA GO:0005759 mitochondrial matrix NAS GO:0005777 peroxisome ISS GO:0005829 cytosol IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0031012 extracellular matrix IDA GO:0031410 cytoplasmic vesicle IDA GO:0032839 dendrite cytoplasm IDA GO:0043025 neuronal cell body IDA GO:0043234 protein complex IDA molecular_function GO:0004784 superoxide dismutase activity IDA GO:0005507 copper ion binding IDA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IDA GO:0016491 oxidoreductase activity IEA GO:0030346 protein phosphatase 2B binding IDA GO:0042803 protein homodimerization activity NAS GO:0046872 metal ion binding IEA GO:0051087 chaperone binding IPI

Protein-protein interaction details for SOD1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCL2 Affinity Capture-Western physical 15233914 BCL2 Affinity Capture-Western physical 15233914 BCL2 Reconstituted Complex physical 15233914 BCL2 Reconstituted Complex physical 15233914 HECW1 Affinity Capture-Western physical 14684739 SSR4 Affinity Capture-Western physical 14684739 CCS Reconstituted Complex physical 9726962 CCS Affinity Capture-Western physical 9726962 RNF19A Affinity Capture-Western physical 17666395 UBC Affinity Capture-Western physical 17666395 PARK7 PCA physical 20406884 HSPA8 Affinity Capture-MS physical 15358145 HSPA4 Affinity Capture-MS physical 15358145 PSMD4 Affinity Capture-Western physical 15358145 STUB1 Affinity Capture-Western physical 15358145 HSPA4 Affinity Capture-Western physical 15358145 UBC Affinity Capture-Western physical 15358145 HSPA4 Affinity Capture-Western physical 15198682 RNF19A Affinity Capture-Western physical 12145308 UBC Affinity Capture-Western physical 12145308 RNF19A Biochemical Activity physical 12145308 UBC Affinity Capture-Western physical 15456787 RNF19A Affinity Capture-Western physical 17157513 STUB1 Affinity Capture-Western physical 17157513 UBC Affinity Capture-Western physical 17157513 CCS Affinity Capture-Western physical 20154138 MARCH5 Affinity Capture-Western physical 19741096 UBC Affinity Capture-Western physical 19741096 UBC Reconstituted Complex physical 19741096 MARCH5 Biochemical Activity physical 19741096 UBC Affinity Capture-Western physical 19661182 UBC Reconstituted Complex physical 19661182 AMFR Biochemical Activity physical 19661182 AMFR Affinity Capture-Western physical 19661182 AMFR Co-localization physical 19661182 DYNLT1 Reconstituted Complex physical 21252941 DYNLT1 Co-fractionation physical 21252941 UBC FRET physical 17992192 HSPA4 FRET physical 17992192