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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for SOX2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001649
osteoblast differentiation
IDA
GO:0001654
eye development
IEP
GO:0001714
endodermal cell fate specification
IDA
GO:0006325
chromatin organization
NAS
GO:0006351
transcription, DNA-dependent
IDA
GO:0006351
transcription, DNA-dependent
NAS
GO:0006355
regulation of transcription, DNA-dependent
IDA
GO:0006355
regulation of transcription, DNA-dependent
NAS
GO:0007050
cell cycle arrest
IDA
GO:0007275
multicellular organismal development
IEA
GO:0009611
response to wounding
IEP
GO:0010468
regulation of gene expression
IMP
GO:0021781
glial cell fate commitment
NAS
GO:0021983
pituitary gland development
IEP
GO:0030900
forebrain development
IEP
GO:0035019
somatic stem cell maintenance
IDA
GO:0035019
somatic stem cell maintenance
IMP
GO:0043281
regulation of cysteine-type endopeptidase activity involved in apoptotic process
IDA
GO:0043410
positive regulation of MAPKKK cascade
IDA
GO:0045665
negative regulation of neuron differentiation
ISS
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0048839
inner ear development
IEP
GO:0050680
negative regulation of epithelial cell proliferation
IDA
GO:0070848
response to growth factor stimulus
IDA
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IDA
cellular_component
GO:0005634
nucleus
IC
GO:0005634
nucleus
IDA
GO:0005634
nucleus
NAS
GO:0005667
transcription factor complex
TAS
GO:0005737
cytoplasm
IDA
GO:0005829
cytosol
IDA
molecular_function
GO:0003677
DNA binding
IDA
GO:0003677
DNA binding
NAS
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
NAS
GO:0005515
protein binding
IPI
GO:0035198
miRNA binding
IDA
GO:0043565
sequence-specific DNA binding
IDA
GO:0044212
transcription regulatory region DNA binding
IDA
Protein-protein interaction details for SOX2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
POU5F1
Reconstituted Complex
physical
12923055
PAX6
Affinity Capture-Western
physical
12710953
PAX6
Affinity Capture-Western
physical
12710953
ALX4
Two-hybrid
physical
20211142
MECP2
Affinity Capture-Western
physical
20368621
MECP2
Affinity Capture-Western
physical
20368621
ZNF281
Affinity Capture-Western
physical
18757296
XPO1
Reconstituted Complex
physical
19591226