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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Lrrk2 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000165
MAPKKK cascade
ISO
GO:0000186
activation of MAPKK activity
ISO
GO:0001934
positive regulation of protein phosphorylation
ISO
GO:0006468
protein phosphorylation
ISA
GO:0006979
response to oxidative stress
ISO
GO:0007264
small GTPase mediated signal transduction
IEA
GO:0007406
negative regulation of neuroblast proliferation
ISO
GO:0007528
neuromuscular junction development
ISO
GO:0008340
determination of adult lifespan
ISO
GO:0010508
positive regulation of autophagy
IMP
GO:0010942
positive regulation of cell death
ISO
GO:0014043
negative regulation of neuron maturation
ISO
GO:0016310
phosphorylation
IEA
GO:0018105
peptidyl-serine phosphorylation
ISO
GO:0021772
olfactory bulb development
ISO
GO:0022028
tangential migration from the subventricular zone to the olfactory bulb
ISO
GO:0031398
positive regulation of protein ubiquitination
ISO
GO:0032436
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
IMP
GO:0035564
regulation of kidney size
IMP
GO:0035640
exploration behavior
ISO
GO:0040012
regulation of locomotion
ISO
GO:0042391
regulation of membrane potential
ISO
GO:0043068
positive regulation of programmed cell death
ISO
GO:0043547
positive regulation of GTPase activity
ISO
GO:0046777
protein autophosphorylation
ISA
GO:0046777
protein autophosphorylation
ISO
GO:0048312
intracellular distribution of mitochondria
ISO
GO:0060161
positive regulation of dopamine receptor signaling pathway
ISO
GO:0061002
negative regulation of dendritic spine morphogenesis
ISO
GO:0070997
neuron death
ISO
GO:2000173
negative regulation of branching morphogenesis of a nerve
ISO
cellular_component
GO:0005622
intracellular
ISO
GO:0005624
membrane fraction
ISO
GO:0005737
cytoplasm
ISO
GO:0005792
microsome
ISO
GO:0005802
trans-Golgi network
IDA
GO:0005886
plasma membrane
IDA
GO:0008021
synaptic vesicle
IDA
GO:0019717
synaptosome
ISO
GO:0030424
axon
ISO
GO:0030425
dendrite
ISO
GO:0032473
external side of mitochondrial outer membrane
ISO
GO:0045121
membrane raft
IDA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0004672
protein kinase activity
ISO
GO:0004674
protein serine/threonine kinase activity
ISO
GO:0004708
MAP kinase kinase activity
ISO
GO:0005096
GTPase activator activity
ISO
GO:0005488
binding
IEA
GO:0005524
ATP binding
IEA
GO:0005525
GTP binding
ISA
GO:0005525
GTP binding
ISO
GO:0015631
tubulin binding
ISO
GO:0016301
kinase activity
IEA
GO:0016740
transferase activity
IEA
GO:0016772
transferase activity, transferring phosphorus-containing groups
IEA
GO:0034211
GTP-dependent protein kinase activity
ISA
GO:0034211
GTP-dependent protein kinase activity
ISO
GO:0042803
protein homodimerization activity
ISO
Protein-protein interaction details for Lrrk2 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Stub1
Affinity Capture-Western
physical
19196961