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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SRC (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006468 protein phosphorylation IDA GO:0006468 protein phosphorylation TAS GO:0007165 signal transduction TAS GO:0007172 signal complex assembly TAS GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0007243 intracellular protein kinase cascade IDA GO:0007265 Ras protein signal transduction TAS GO:0007411 axon guidance TAS GO:0007596 blood coagulation TAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0016044 cellular membrane organization TAS GO:0016310 phosphorylation TAS GO:0018108 peptidyl-tyrosine phosphorylation IEA GO:0030168 platelet activation TAS GO:0030900 forebrain development IEA GO:0031295 T cell costimulation TAS GO:0033146 regulation of estrogen receptor signaling pathway IEA GO:0033625 positive regulation of integrin activation TAS GO:0034329 cell junction assembly TAS GO:0043114 regulation of vascular permeability TAS GO:0044419 interspecies interaction between organisms IEA GO:0045124 regulation of bone resorption TAS GO:0045453 bone resorption ISS GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048477 oogenesis IEA GO:0050900 leukocyte migration TAS GO:0060065 uterus development IEA GO:0060444 branching involved in mammary gland duct morphogenesis IEA GO:0070555 response to interleukin-1 IMP cellular_component GO:0005739 mitochondrion IEA GO:0005743 mitochondrial inner membrane IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0005901 caveola IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IDA GO:0004672 protein kinase activity TAS GO:0004713 protein tyrosine kinase activity TAS GO:0004715 non-membrane spanning protein tyrosine kinase activity TAS GO:0005070 SH3/SH2 adaptor activity TAS GO:0005102 receptor binding IPI GO:0005178 integrin binding TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016301 kinase activity TAS GO:0020037 heme binding IDA GO:0042169 SH2 domain binding IPI GO:0044325 ion channel binding IPI GO:0046875 ephrin receptor binding IPI

Protein-protein interaction details for SRC (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EPHB2 Two-hybrid physical 9632142 ND2 Two-hybrid physical 15069201 TRIP6 Affinity Capture-Western physical 14688263 CDH1 Affinity Capture-Western physical 10744074 PIK3R1 Affinity Capture-Western physical 10487518 ESR2 Affinity Capture-Western physical 11032808 BCAR1 Reconstituted Complex physical 10487518 BCAR1 Affinity Capture-Western physical 10487518 BCAR1 Reconstituted Complex physical 12397603 ESR1 Affinity Capture-Western physical 11032808 AR Affinity Capture-Western physical 11032808 SNURF Phenotypic Enhancement genetic 11696545 AR Affinity Capture-Western physical 15466214 PELP1 Affinity Capture-Western physical 15466214 AR Two-hybrid physical 15027889 NCOA6 Affinity Capture-Western physical 12482968 NCOA6 Two-hybrid physical 10567404 NCOA6 Reconstituted Complex physical 10567404 NCOA6 Reconstituted Complex physical 10847592 ND2 Reconstituted Complex physical 15069201 ND2 Affinity Capture-Western physical 15069201 TRPC6 Affinity Capture-Western physical 14761972 GRIN2A Affinity Capture-Western physical 12932824 PLSCR1 Biochemical Activity physical 12871937 PLD2 Biochemical Activity physical 12697812 PLD1 Biochemical Activity physical 12697812 PLD2 Affinity Capture-Western physical 12697812 PLD2 Reconstituted Complex physical 12697812 CTNND1 Affinity Capture-Western physical 12640114 ADRBK1 Affinity Capture-Western physical 12624098 PDE6G Affinity Capture-Western physical 12624098 ADRBK1 Affinity Capture-Western physical 12624098 GRB2 Affinity Capture-Western physical 12624098 PDE6G Affinity Capture-Western physical 12624098 PDE6G Reconstituted Complex physical 12624098 CRK Affinity Capture-Western physical 12615911 BCAR1 Affinity Capture-Western physical 12615911 DOCK1 Affinity Capture-Western physical 12615911 PTK2 Affinity Capture-Western physical 12615911 RXRA Reconstituted Complex physical 10517671 ARR3 Affinity Capture-Western physical 11877451 HNF1A Affinity Capture-Western physical 10777539 HNF1A Reconstituted Complex physical 10777539 ESR1 Affinity Capture-Western physical 11564893 FOXO1 Reconstituted Complex physical 10973497 EP300 Reconstituted Complex physical 10973497 RARA Reconstituted Complex physical 10454579 THRB Reconstituted Complex physical 10454579 ESR1 Reconstituted Complex physical 10454579 TRIP4 Affinity Capture-Western physical 10454579 KHDRBS1 Two-hybrid physical 16169070 PLCG1 Affinity Capture-Western physical 7510703 WAS Affinity Capture-Western physical 8805332 WAS Reconstituted Complex physical 8805332 BCAR1 Affinity Capture-Western physical 11514617 KIFAP3 Biochemical Activity physical 8900189 KHDRBS1 Affinity Capture-Western physical 11960376 BCAR1 Two-hybrid physical 10739664 ADRB2 Affinity Capture-Western physical 11013230 ADRB3 Affinity Capture-Western physical 11013230 ADRB3 Reconstituted Complex physical 11013230 GRB10 Biochemical Activity physical 10871840 MAPK8IP3 Biochemical Activity physical 12226752 AHR Affinity Capture-Western physical 12024042 ARNT Affinity Capture-Western physical 12024042 ARNT Two-hybrid physical 12024042 ARNT Reconstituted Complex physical 12024042 AHR Two-hybrid physical 12024042 AHR Reconstituted Complex physical 12024042 TNFSF11 Affinity Capture-Western physical 10635328 TRAF1 Affinity Capture-Western physical 10635328 TRAF3 Affinity Capture-Western physical 10635328 TRAF6 Affinity Capture-Western physical 10635328 PTPN21 Affinity Capture-Western physical 7519780 SLC9A2 Reconstituted Complex physical 10187839 PTK2 Affinity Capture-Western physical 11980671 AXL Far Western physical 9178760 DOK1 Reconstituted Complex physical 11071635 MAP2 Reconstituted Complex physical 10781592 LRP1 Biochemical Activity physical 11854294 RET Affinity Capture-Western physical 10070972 FYN Protein-peptide physical 9169421 LYN Protein-peptide physical 9169421 EGFR Affinity Capture-Western physical 10358079 STAT1 Affinity Capture-Western physical 10358079 TYRO3 Affinity Capture-Western physical 7537495 PTK2B Affinity Capture-Western physical 10777553 EGFR Affinity Capture-Western physical 10777553 RASA1 Affinity Capture-Western physical 1717825 EFNB1 Biochemical Activity physical 8878483 KHDRBS1 Reconstituted Complex physical 1545818 SYK Biochemical Activity physical 7513017 ASAP1 Two-hybrid physical 9819391 ASAP1 Reconstituted Complex physical 9819391 ASAP1 Affinity Capture-Western physical 9819391 KHDRBS1 Reconstituted Complex physical 10467411 KHDRBS1 Affinity Capture-Western physical 10467411 GAB3 Reconstituted Complex physical 11739737 ERBB2 Reconstituted Complex physical 11940572 RPS6KB1 Biochemical Activity physical 16640565 RPS6KB2 Biochemical Activity physical 16640565 DAG1 Biochemical Activity physical 11724572 DAG1 Reconstituted Complex physical 11724572 DAG1 Affinity Capture-Western physical 11724572 CDC37 Reconstituted Complex physical 11085988 RAF1 Affinity Capture-Western physical 7517401 RAF1 Reconstituted Complex physical 7517401 KHDRBS1 Reconstituted Complex physical 8766817 SKAP1 Reconstituted Complex physical 9195899 ARHGAP17 Reconstituted Complex physical 11431473 STAT1 Affinity Capture-Western physical 9344858 EVL Reconstituted Complex physical 10945997 PECAM1 Affinity Capture-Western physical 10858437 ASAP2 Affinity Capture-Western physical 10022920 PTK2 Reconstituted Complex physical 10085298 PXN Reconstituted Complex physical 10085298 BCAR1 Reconstituted Complex physical 10085298 PTK2 Affinity Capture-Western physical 12387730 CSF1R Affinity Capture-Western physical 7681396 GSN Affinity Capture-Western physical 11577104 ARHGAP32 Reconstituted Complex physical 12454018 ARHGAP32 Affinity Capture-Western physical 12454018 ITK Reconstituted Complex physical 10636929 PTK2 Affinity Capture-Western physical 12558988 MUC1 Affinity Capture-Western physical 11152665 MUC1 Reconstituted Complex physical 11152665 MUC1 Biochemical Activity physical 11152665 EPHB2 Two-hybrid physical 10644995 EPHB2 Reconstituted Complex physical 10644995 SH3BP1 Reconstituted Complex physical 1379745 MET Affinity Capture-Western physical 9837958 RPL10 Reconstituted Complex physical 12138090 WAS Reconstituted Complex physical 8824280 ARHGAP1 Reconstituted Complex physical 8253717 CD44 Affinity Capture-Western physical 11084024 CD44 Reconstituted Complex physical 11084024 PTK2B Reconstituted Complex physical 10521452 GNB2L1 Two-hybrid physical 9584165 GNB2L1 Reconstituted Complex physical 9584165 GNB2L1 Affinity Capture-Western physical 9584165 GNB2L1 Affinity Capture-Western physical 9584165 PRKCZ Affinity Capture-Western physical 10527887 PRKCZ Affinity Capture-Western physical 10527887 GRB2 Affinity Capture-Western physical 11964172 PTPRA Affinity Capture-Western physical 11923305 STAT3 Affinity Capture-Western physical 8657134 STAT3 Reconstituted Complex physical 8657134 BMX Affinity Capture-Western physical 10688651 DAB2 Reconstituted Complex physical 12473651 DAB2 Affinity Capture-Western physical 12473651 CSK Reconstituted Complex physical 7513429 EGFR Affinity Capture-Western physical 10971656 MUC1 Affinity Capture-Western physical 11483589 MUC1 Reconstituted Complex physical 11483589 CAV1 Reconstituted Complex physical 8910575 MPZL1 Affinity Capture-Western physical 11751924 EPS8 Biochemical Activity physical 10395945 EPS8 Reconstituted Complex physical 10395945 DDR2 Affinity Capture-Western physical 11884411 GAB2 Affinity Capture-Western physical 10391903 PTK2B Affinity Capture-Western physical 8849729 PTK2B Reconstituted Complex physical 8849729 SRF Reconstituted Complex physical 9786846 SRF Two-hybrid physical 9786846 MATK Biochemical Activity physical 7530249 MYLK Affinity Capture-Western physical 10362724 SHB Reconstituted Complex physical 7537362 SHB Affinity Capture-Western physical 7537362 GRIN2A Reconstituted Complex physical 10458595 GRIN2A Affinity Capture-Western physical 10458595 TRPV4 Affinity Capture-Western physical 12538589 CAV2 Reconstituted Complex physical 12091389 MICAL1 Reconstituted Complex physical 11827972 SYN1 Affinity Capture-Western physical 10899172 HSP90AA1 Affinity Capture-Western physical 1310678 RASA1 Biochemical Activity physical 11389730 CDC25C Biochemical Activity physical 11389730 CD46 Biochemical Activity physical 10657632 ESR2 Two-hybrid physical 11013076 ESR1 Two-hybrid physical 11013076 PTK2 Two-hybrid physical 9822703 EPHB2 Reconstituted Complex physical 9632142 EPHB2 Affinity Capture-Western physical 9632142 EPHB2 Reconstituted Complex physical 9632142 EPHA3 Reconstituted Complex physical 9632142 EPHA4 Reconstituted Complex physical 9632142 NCOA6 Two-hybrid physical 11158331 RARA Two-hybrid physical 12612084 ABL1 Reconstituted Complex physical 11494128 FLNA Two-hybrid physical 20936779 EGFR Affinity Capture-Western physical 17158602 PDGFRB Affinity Capture-Western physical 17158602 PPARD Reconstituted Complex physical 16930961 CARM1 Biochemical Activity physical 16923966 BRCA1 Affinity Capture-Western physical 16860316 CREBBP Affinity Capture-Western physical 16860316 BRCA1 Affinity Capture-Western physical 16860316 BRCA1 Reconstituted Complex physical 16860316 HDAC3 Affinity Capture-Western physical 16532030 HDAC3 Affinity Capture-Western physical 16532030 HDAC3 Biochemical Activity physical 16532030 VDR Co-localization physical 16434701 NR3C1 Affinity Capture-Western physical 16423881 SMAD3 Affinity Capture-Western physical 16423881 VDR Two-hybrid physical 12893883 PPARA FRET physical 12163133 SF1 Affinity Capture-Western physical 16002533 NR4A1 Affinity Capture-Western physical 16002533 SMARCC1 Reconstituted Complex physical 15923603 SMARCC1 Far Western physical 15923603 VDR Two-hybrid physical 15919723 ETS1 Affinity Capture-Western physical 15788656 ETS2 Affinity Capture-Western physical 15788656 ESR1 Reconstituted Complex physical 15784253 STAT3 Reconstituted Complex physical 15313931 STAT3 Affinity Capture-Western physical 15313931 PRDM2 Affinity Capture-Western physical 15282304 PRDM2 Affinity Capture-Western physical 15282304 FGFR1 Affinity Capture-Western physical 20388777 ESR1 Reconstituted Complex physical 15140878 RXRA Reconstituted Complex physical 15140878 THRA Reconstituted Complex physical 15140878 RXRA Reconstituted Complex physical 15116119 AR Two-hybrid physical 15062576 THRB Reconstituted Complex physical 14985366 SNW1 Reconstituted Complex physical 14985122 ESR1 Two-hybrid physical 14766010 ESR1 Affinity Capture-Western physical 14766010 CBL Affinity Capture-Western physical 11994282 HCK Affinity Capture-Western physical 11896602 ESR1 Affinity Capture-Western physical 17400812 HDAC3 Affinity Capture-Western physical 17699109 EFNA5 Reconstituted Complex physical 17631495 PPARGC1B Reconstituted Complex physical 17631495 SMARCE1 Reconstituted Complex physical 17363140 ARID1A Reconstituted Complex physical 17363140 RARA Reconstituted Complex physical 17363140 ESR1 Reconstituted Complex physical 17363140 RARB Reconstituted Complex physical 17363140 RARG Reconstituted Complex physical 17363140 RXRA Reconstituted Complex physical 17363140 ESRRA Affinity Capture-MS physical 20400511 VDR Affinity Capture-Western physical 20371703 RARA Reconstituted Complex physical 20338915 NR1H4 Reconstituted Complex physical 20338915 CFL1 Biochemical Activity physical 19802004 CDH1 Affinity Capture-Western physical 21685945 CBLL1 Affinity Capture-Western physical 21685945 TNK2 Reconstituted Complex physical 19144635 NDFIP2 Affinity Capture-Western physical 20534535 CBLL1 Affinity Capture-Western physical 18057010 CDH1 Affinity Capture-Western physical 18057010 TLR4 Affinity Capture-Western physical 21911421 TLR9 Affinity Capture-Western physical 21911421 STUB1 Reconstituted Complex physical 21911421 STUB1 Affinity Capture-Western physical 21911421 STUB1 Co-localization physical 21911421 UBC Affinity Capture-Western physical 21911421 STUB1 Biochemical Activity physical 21911421 SRC Biochemical Activity physical 21911421 ESR1 Reconstituted Complex physical 18451880 SYTL2 Affinity Capture-MS physical 16051665 WDHD1 Affinity Capture-MS physical 16051665 UBR5 Affinity Capture-MS physical 16051665 RBBP6 Affinity Capture-MS physical 16051665 TRIP11 Affinity Capture-MS physical 16051665 ITCH Affinity Capture-MS physical 16051665 VCP Affinity Capture-MS physical 16051665 KCTD3 Affinity Capture-MS physical 16051665 HSPA5 Affinity Capture-MS physical 16051665 HSPA2 Affinity Capture-MS physical 16051665 UBC Affinity Capture-Western physical 20584982 RORB Two-hybrid physical 15604093 NR1H2 Two-hybrid physical 15604093 NR1H3 Two-hybrid physical 15604093 VDR Two-hybrid physical 15604093 NR1I2 Two-hybrid physical 15604093 NR1I3 Two-hybrid physical 15604093 HNF4G Two-hybrid physical 15604093 RXRB Two-hybrid physical 15604093 ESR1 Two-hybrid physical 15604093 ESR2 Two-hybrid physical 15604093 ESRRA Two-hybrid physical 15604093 ESRRG Two-hybrid physical 15604093 NR3C2 Two-hybrid physical 15604093 NR5A2 Two-hybrid physical 15604093 VDR Reconstituted Complex physical 12796488 VDR Two-hybrid physical 12796488 RARA Two-hybrid physical 17641689 CRMP1 Two-hybrid physical 21900206 CBL Affinity Capture-Western physical 22203672 EGLN1 Affinity Capture-Western physical 21335603 EGLN1 Affinity Capture-Western physical 21335603 EGLN1 Reconstituted Complex physical 21335603 EGLN1 Reconstituted Complex physical 21335603 SRC Biochemical Activity physical 21335603 EGLN1 Biochemical Activity physical 21335603 ESR1 Affinity Capture-Western physical 15020686 BCAR1 Affinity Capture-Western physical 15020686 SRC Affinity Capture-Western physical 15020686