Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for SRF (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001569
patterning of blood vessels
IEA
GO:0001701
in utero embryonic development
IEA
GO:0001707
mesoderm formation
IEA
GO:0001829
trophectodermal cell differentiation
IDA
GO:0001947
heart looping
IEA
GO:0001947
heart looping
ISS
GO:0002042
cell migration involved in sprouting angiogenesis
IEA
GO:0002042
cell migration involved in sprouting angiogenesis
IMP
GO:0006366
transcription from RNA polymerase II promoter
IDA
GO:0007015
actin filament organization
IEA
GO:0007275
multicellular organismal development
IEA
GO:0007369
gastrulation
IEA
GO:0007507
heart development
IEA
GO:0007507
heart development
ISS
GO:0007616
long-term memory
IEA
GO:0008285
negative regulation of cell proliferation
IEA
GO:0009636
response to toxin
TAS
GO:0009725
response to hormone stimulus
IDA
GO:0010735
positive regulation of transcription via serum response element binding
IDA
GO:0030155
regulation of cell adhesion
IEA
GO:0030336
negative regulation of cell migration
IEA
GO:0034097
response to cytokine stimulus
IMP
GO:0034097
response to cytokine stimulus
NAS
GO:0045597
positive regulation of cell differentiation
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0045987
positive regulation of smooth muscle contraction
IDA
GO:0046716
muscle cell homeostasis
IEA
GO:0046716
muscle cell homeostasis
ISS
GO:0048589
developmental growth
IEA
GO:0048666
neuron development
TAS
GO:0051150
regulation of smooth muscle cell differentiation
TAS
GO:0051491
positive regulation of filopodium assembly
IEA
GO:0060055
angiogenesis involved in wound healing
TAS
GO:0060261
positive regulation of transcription initiation from RNA polymerase II promoter
IDA
GO:0090009
primitive streak formation
IEA
GO:0090398
cellular senescence
IMP
cellular_component
GO:0000790
nuclear chromatin
IEA
GO:0005634
nucleus
IDA
GO:0005634
nucleus
IEA
GO:0005730
nucleolus
IDA
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
IEA
GO:0005737
cytoplasm
TAS
GO:0005783
endoplasmic reticulum
IDA
molecular_function
GO:0001076
RNA polymerase II transcription factor binding transcription factor activity
IEA
GO:0001077
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IEA
GO:0005515
protein binding
IPI
GO:0008134
transcription factor binding
IPI
GO:0010736
serum response element binding
IDA
GO:0010736
serum response element binding
IEA
GO:0042803
protein homodimerization activity
IPI
GO:0043565
sequence-specific DNA binding
IEA
Protein-protein interaction details for SRF (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
NCOA6
Reconstituted Complex
physical
10847592
MYOCD
Affinity Capture-Western
physical
15014501
MKL1
Affinity Capture-Western
physical
14565952
MKL2
Affinity Capture-Western
physical
14565952
PML
Reconstituted Complex
physical
12622724
PML
Affinity Capture-Western
physical
12622724
CREBBP
Affinity Capture-Western
physical
12622724
PML
Affinity Capture-Western
physical
12622724
CREBBP
Affinity Capture-Western
physical
12622724
SSRP1
Affinity Capture-Western
physical
10336466
RXRG
Reconstituted Complex
physical
11641790
RARG
Reconstituted Complex
physical
11641790
GATA4
Affinity Capture-Western
physical
11003651
GATA4
Reconstituted Complex
physical
11003651
REL
Reconstituted Complex
physical
8670842
RELA
Reconstituted Complex
physical
8670842
NFYA
Two-hybrid
physical
10571058
NFYA
Reconstituted Complex
physical
10571058
GTF2F1
Two-hybrid
physical
7854423
GATA4
Affinity Capture-Western
physical
11158291
GATA4
Reconstituted Complex
physical
11158291
NKX3-1
Affinity Capture-Western
physical
10993896
MYOG
Reconstituted Complex
physical
8617811
FLI1
Reconstituted Complex
physical
10606656
ELK1
Reconstituted Complex
physical
9010223
TEAD1
Reconstituted Complex
physical
11136726
TEAD1
Affinity Capture-Western
physical
11136726
TEAD1
Far Western
physical
11136726
SP1
Reconstituted Complex
physical
10082523
MYOG
Reconstituted Complex
physical
10082523
ASCC1
Reconstituted Complex
physical
12077347
ASCC2
Reconstituted Complex
physical
12077347
ASCC3
Reconstituted Complex
physical
12077347
ASCC1
Two-hybrid
physical
12077347
ASCC2
Two-hybrid
physical
12077347
ASCC3
Two-hybrid
physical
12077347
NCOR2
Two-hybrid
physical
10777532
NCOR2
Two-hybrid
physical
10777532
NCOR2
Reconstituted Complex
physical
10777532
NCOR2
Reconstituted Complex
physical
10777532
GTF2I
Co-purification
physical
9334314
ELK4
Co-crystal Structure
physical
11406578
GTF2I
Reconstituted Complex
physical
9584171
CD63
Two-hybrid
physical
9271374
ATF6
Two-hybrid
physical
9271374
ELK4
Two-hybrid
physical
9271374
ATF6
Reconstituted Complex
physical
9271374
CEBPB
Affinity Capture-Western
physical
10318842
CEBPB
Two-hybrid
physical
10318842
CEBPB
Reconstituted Complex
physical
9032301
GTF2F1
Reconstituted Complex
physical
8106390
SRC
Reconstituted Complex
physical
9786846
SRC
Two-hybrid
physical
9786846
SMARCA4
Affinity Capture-Western
physical
19342595
SMARCA4
Affinity Capture-Western
physical
19342595
MYOCD
Affinity Capture-Western
physical
19342595
MYOCD
Affinity Capture-Western
physical
19342595
HDAC3
Affinity Capture-Western
physical
17158926
SMAD7
Affinity Capture-Western
physical
16690609
SMAD7
Affinity Capture-Western
physical
16690609
EPC1
Affinity Capture-Western
physical
19359245
EPC1
Affinity Capture-Western
physical
19359245
HDAC4
Affinity Capture-Western
physical
12663674
HDAC4
Reconstituted Complex
physical
12663674
HDAC4
Reconstituted Complex
physical
12663674
KAT5
Reconstituted Complex
physical
15591049
PELP1
Co-localization
physical
15456770
PELP1
Co-localization
physical
15456770
MKL1
Affinity Capture-Western
physical
17599918
SMARCA4
Affinity Capture-Western
physical
17599918
MKL1
Affinity Capture-Western
physical
17599918
CSNK2A1
Biochemical Activity
physical
1740119
SRF
Reconstituted Complex
physical
2046671
CNTN2
Two-hybrid
physical
19609363
MKL1
Affinity Capture-Western
physical
21965288