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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SRF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001569patterning of blood vesselsIEA
GO:0001701in utero embryonic developmentIEA
GO:0001707mesoderm formationIEA
GO:0001829trophectodermal cell differentiationIDA
GO:0001947heart loopingIEA
GO:0001947heart loopingISS
GO:0002042cell migration involved in sprouting angiogenesisIEA
GO:0002042cell migration involved in sprouting angiogenesisIMP
GO:0006366transcription from RNA polymerase II promoterIDA
GO:0007015actin filament organizationIEA
GO:0007275multicellular organismal developmentIEA
GO:0007369gastrulationIEA
GO:0007507heart developmentIEA
GO:0007507heart developmentISS
GO:0007616long-term memoryIEA
GO:0008285negative regulation of cell proliferationIEA
GO:0009636response to toxinTAS
GO:0009725response to hormone stimulusIDA
GO:0010735positive regulation of transcription via serum response element bindingIDA
GO:0030155regulation of cell adhesionIEA
GO:0030336negative regulation of cell migrationIEA
GO:0034097response to cytokine stimulusIMP
GO:0034097response to cytokine stimulusNAS
GO:0045597positive regulation of cell differentiationIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0045987positive regulation of smooth muscle contractionIDA
GO:0046716muscle cell homeostasisIEA
GO:0046716muscle cell homeostasisISS
GO:0048589developmental growthIEA
GO:0048666neuron developmentTAS
GO:0051150regulation of smooth muscle cell differentiationTAS
GO:0051491positive regulation of filopodium assemblyIEA
GO:0060055angiogenesis involved in wound healingTAS
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoterIDA
GO:0090009primitive streak formationIEA
GO:0090398cellular senescenceIMP
cellular_component
GO:0000790nuclear chromatinIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005737cytoplasmTAS
GO:0005783endoplasmic reticulumIDA
molecular_function
GO:0001076RNA polymerase II transcription factor binding transcription factor activityIEA
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingIPI
GO:0010736serum response element bindingIDA
GO:0010736serum response element bindingIEA
GO:0042803protein homodimerization activityIPI
GO:0043565sequence-specific DNA bindingIEA

Protein-protein interaction details for SRF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NCOA6Reconstituted Complexphysical10847592
MYOCDAffinity Capture-Westernphysical15014501
MKL1Affinity Capture-Westernphysical14565952
MKL2Affinity Capture-Westernphysical14565952
PMLReconstituted Complexphysical12622724
PMLAffinity Capture-Westernphysical12622724
CREBBPAffinity Capture-Westernphysical12622724
PMLAffinity Capture-Westernphysical12622724
CREBBPAffinity Capture-Westernphysical12622724
SSRP1Affinity Capture-Westernphysical10336466
RXRGReconstituted Complexphysical11641790
RARGReconstituted Complexphysical11641790
GATA4Affinity Capture-Westernphysical11003651
GATA4Reconstituted Complexphysical11003651
RELReconstituted Complexphysical8670842
RELAReconstituted Complexphysical8670842
NFYATwo-hybridphysical10571058
NFYAReconstituted Complexphysical10571058
GTF2F1Two-hybridphysical7854423
GATA4Affinity Capture-Westernphysical11158291
GATA4Reconstituted Complexphysical11158291
NKX3-1Affinity Capture-Westernphysical10993896
MYOGReconstituted Complexphysical8617811
FLI1Reconstituted Complexphysical10606656
ELK1Reconstituted Complexphysical9010223
TEAD1Reconstituted Complexphysical11136726
TEAD1Affinity Capture-Westernphysical11136726
TEAD1Far Westernphysical11136726
SP1Reconstituted Complexphysical10082523
MYOGReconstituted Complexphysical10082523
ASCC1Reconstituted Complexphysical12077347
ASCC2Reconstituted Complexphysical12077347
ASCC3Reconstituted Complexphysical12077347
ASCC1Two-hybridphysical12077347
ASCC2Two-hybridphysical12077347
ASCC3Two-hybridphysical12077347
NCOR2Two-hybridphysical10777532
NCOR2Two-hybridphysical10777532
NCOR2Reconstituted Complexphysical10777532
NCOR2Reconstituted Complexphysical10777532
GTF2ICo-purificationphysical9334314
ELK4Co-crystal Structurephysical11406578
GTF2IReconstituted Complexphysical9584171
CD63Two-hybridphysical9271374
ATF6Two-hybridphysical9271374
ELK4Two-hybridphysical9271374
ATF6Reconstituted Complexphysical9271374
CEBPBAffinity Capture-Westernphysical10318842
CEBPBTwo-hybridphysical10318842
CEBPBReconstituted Complexphysical9032301
GTF2F1Reconstituted Complexphysical8106390
SRCReconstituted Complexphysical9786846
SRCTwo-hybridphysical9786846
SMARCA4Affinity Capture-Westernphysical19342595
SMARCA4Affinity Capture-Westernphysical19342595
MYOCDAffinity Capture-Westernphysical19342595
MYOCDAffinity Capture-Westernphysical19342595
HDAC3Affinity Capture-Westernphysical17158926
SMAD7Affinity Capture-Westernphysical16690609
SMAD7Affinity Capture-Westernphysical16690609
EPC1Affinity Capture-Westernphysical19359245
EPC1Affinity Capture-Westernphysical19359245
HDAC4Affinity Capture-Westernphysical12663674
HDAC4Reconstituted Complexphysical12663674
HDAC4Reconstituted Complexphysical12663674
KAT5Reconstituted Complexphysical15591049
PELP1Co-localizationphysical15456770
PELP1Co-localizationphysical15456770
MKL1Affinity Capture-Westernphysical17599918
SMARCA4Affinity Capture-Westernphysical17599918
MKL1Affinity Capture-Westernphysical17599918
CSNK2A1Biochemical Activityphysical1740119
SRFReconstituted Complexphysical2046671
CNTN2Two-hybridphysical19609363
MKL1Affinity Capture-Westernphysical21965288