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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SYT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0005513 detection of calcium ion TAS GO:0007268 synaptic transmission TAS GO:0007269 neurotransmitter secretion TAS GO:0014047 glutamate secretion TAS GO:0016079 synaptic vesicle exocytosis IEA GO:0017157 regulation of exocytosis TAS GO:0017158 regulation of calcium ion-dependent exocytosis IEA GO:0051260 protein homooligomerization TAS cellular_component GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0008021 synaptic vesicle IEA GO:0008021 synaptic vesicle TAS GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0030054 cell junction IEA GO:0030666 endocytic vesicle membrane TAS GO:0030672 synaptic vesicle membrane IEA GO:0031045 dense core granule IEA GO:0031410 cytoplasmic vesicle IEA GO:0042584 chromaffin granule membrane IEA GO:0042734 presynaptic membrane IEA GO:0043005 neuron projection IEA GO:0043229 intracellular organelle IEA GO:0045202 synapse IEA GO:0060201 clathrin sculpted acetylcholine transport vesicle membrane TAS GO:0060203 clathrin sculpted glutamate transport vesicle membrane TAS GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane TAS GO:0070083 clathrin sculpted monoamine transport vesicle membrane TAS molecular_function GO:0005215 transporter activity IEA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0005516 calmodulin binding IEA GO:0005543 phospholipid binding IEA GO:0005545 1-phosphatidylinositol binding TAS GO:0017075 syntaxin-1 binding TAS GO:0042802 identical protein binding IEA GO:0048306 calcium-dependent protein binding IEA GO:0050750 low-density lipoprotein particle receptor binding IDA

Protein-protein interaction details for SYT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SV2B Affinity Capture-Western physical 15466855 C6orf15 Affinity Capture-Western physical 15466855 SV2C Affinity Capture-Western physical 15466855 GOLM1 Two-hybrid physical 16169070 S100A13 Co-purification physical 9712836 CALM1 Reconstituted Complex physical 8901523 STX1A Reconstituted Complex physical 9010211 STON2 Reconstituted Complex physical 11381094 SYNCRIP Reconstituted Complex physical 10734137 SNAP25 Reconstituted Complex physical 10692432 CACNA1A Reconstituted Complex physical 9303303 SNAP25 Reconstituted Complex physical 12062043 STX1A Reconstituted Complex physical 10397765 STX1A Reconstituted Complex physical 10397765 STX2 Reconstituted Complex physical 10397765 STX3 Reconstituted Complex physical 10397765 STX4 Reconstituted Complex physical 10397765 STON2 Reconstituted Complex physical 11454741 S100A13 Reconstituted Complex physical 11432880 FGF1 Reconstituted Complex physical 11432880 IKBKG Reconstituted Complex physical 20098747 IKBKG Affinity Capture-Western physical 20098747 IKBKG Two-hybrid physical 20098747 RBM14 Reconstituted Complex physical 15919756 RBM14 Reconstituted Complex physical 15919756 SIN3A Two-hybrid physical 15467731 SIN3A Reconstituted Complex physical 15467731