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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TAP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001916 positive regulation of T cell mediated cytotoxicity IBA GO:0002474 antigen processing and presentation of peptide antigen via MHC class I TAS GO:0015031 protein transport IEA GO:0015833 peptide transport IBA GO:0015833 peptide transport IGI GO:0015833 peptide transport IMP GO:0019060 intracellular transport of viral proteins in host cell IMP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IMP GO:0042270 protection from natural killer cell mediated cytotoxicity IEA GO:0044419 interspecies interaction between organisms IEA GO:0046967 cytosol to ER transport IMP GO:0055085 transmembrane transport IBA GO:0055085 transmembrane transport IEA cellular_component GO:0005743 mitochondrial inner membrane IRD GO:0005783 endoplasmic reticulum IEA GO:0005789 endoplasmic reticulum membrane TAS GO:0005792 microsome IEA GO:0005829 cytosol NAS GO:0005886 plasma membrane IBA GO:0016020 membrane IEA GO:0016021 integral to membrane IDA GO:0016021 integral to membrane IEA GO:0030176 integral to endoplasmic reticulum membrane IDA GO:0042825 TAP complex IBA GO:0042825 TAP complex IDA GO:0042825 TAP complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0005215 transporter activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0005524 ATP binding IEA GO:0015197 peptide transporter activity IEA GO:0015197 peptide transporter activity IGI GO:0015197 peptide transporter activity IMP GO:0015421 oligopeptide-transporting ATPase activity IBA GO:0016887 ATPase activity IEA GO:0042288 MHC class I protein binding IBA GO:0042605 peptide antigen binding IBA GO:0042605 peptide antigen binding IEA GO:0042605 peptide antigen binding NAS GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA GO:0042803 protein homodimerization activity IEA GO:0042803 protein homodimerization activity ISS GO:0043531 ADP binding IDA GO:0043531 ADP binding IEA GO:0046978 TAP1 binding IBA GO:0046978 TAP1 binding IEA GO:0046978 TAP1 binding ISS GO:0046979 TAP2 binding IBA GO:0046979 TAP2 binding IPI GO:0046980 tapasin binding IBA GO:0046980 tapasin binding IEA GO:0046982 protein heterodimerization activity IEA

Protein-protein interaction details for TAP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID KRTAP4-12 Two-hybrid physical 16189514 MDFI Two-hybrid physical 16189514 HLA-G Affinity Capture-Western physical 9103419 PDIA3 Affinity Capture-MS physical 9545232 TAP2 Reconstituted Complex physical 11381133 TAPBP Reconstituted Complex physical 12213826 TAPBP Affinity Capture-Western physical 11884415 COPB1 Affinity Capture-Western physical 11884415 COPG Affinity Capture-Western physical 11884415 TAPBP Affinity Capture-Western physical 11884415 HLA-A Affinity Capture-Western physical 11884415 HLA-A Affinity Capture-Western physical 11884415