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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HNF1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001824 blastocyst development IEA GO:0001889 liver development IEA GO:0001890 placenta development IEA GO:0006338 chromatin remodeling IEA GO:0006351 transcription, DNA-dependent IDA GO:0006357 regulation of transcription from RNA polymerase II promoter IDA GO:0006633 fatty acid biosynthetic process IEA GO:0006699 bile acid biosynthetic process IEA GO:0006783 heme biosynthetic process IEA GO:0006979 response to oxidative stress IEA GO:0008104 protein localization IEA GO:0008203 cholesterol metabolic process IEA GO:0009749 response to glucose stimulus IEA GO:0015721 bile acid and bile salt transport IEA GO:0015908 fatty acid transport IEA GO:0030073 insulin secretion IMP GO:0030111 regulation of Wnt receptor signaling pathway IEA GO:0030326 embryonic limb morphogenesis IEA GO:0031018 endocrine pancreas development IEA GO:0035565 regulation of pronephros size IMP GO:0035623 renal glucose absorption IMP GO:0042593 glucose homeostasis IMP GO:0043691 reverse cholesterol transport IEA GO:0045453 bone resorption IEA GO:0045892 negative regulation of transcription, DNA-dependent IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0046323 glucose import IMP GO:0046883 regulation of hormone secretion IEA GO:0048341 paraxial mesoderm formation IEA GO:0048608 reproductive structure development IEA GO:0050796 regulation of insulin secretion IEA GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IGI GO:0060395 SMAD protein signal transduction IEA cellular_component GO:0001750 photoreceptor outer segment IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005667 transcription factor complex IEA GO:0005737 cytoplasm IDA GO:0043234 protein complex IDA GO:0045120 pronucleus IEA molecular_function GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription ISS GO:0003677 DNA binding IDA GO:0003677 DNA binding IEA GO:0003690 double-stranded DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI GO:0042803 protein homodimerization activity IEA GO:0042803 protein homodimerization activity IPI GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0046982 protein heterodimerization activity IDA GO:0046982 protein heterodimerization activity IEA GO:0046983 protein dimerization activity IPI

Protein-protein interaction details for HNF1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PCBD1 Affinity Capture-MS physical 17353931 PCBD2 Affinity Capture-MS physical 17353931 CALM3 Affinity Capture-MS physical 17353931 SNRPA1 Affinity Capture-MS physical 17353931 RHPN2 Affinity Capture-MS physical 17353931 CREBBP Affinity Capture-Western physical 10777539 KAT2B Affinity Capture-Western physical 10777539 SRC Affinity Capture-Western physical 10777539 RAC3 Affinity Capture-Western physical 10777539 CREBBP Reconstituted Complex physical 10777539 KAT2B Reconstituted Complex physical 10777539 SRC Reconstituted Complex physical 10777539 RAC3 Reconstituted Complex physical 10777539 EP300 Affinity Capture-Western physical 11978637 EP300 Reconstituted Complex physical 11978637 CDX2 Reconstituted Complex physical 10677375 AES Two-hybrid physical 11266540 HNF1B Reconstituted Complex physical 2044952 HNF1A Reconstituted Complex physical 2044952 FOS Affinity Capture-Western physical 11134330 STAT3 Affinity Capture-Western physical 11134330 PCBD1 Affinity Capture-Western physical 9092652 PCBD1 Reconstituted Complex physical 9092652 PCBD1 Two-hybrid physical 9092652 CREBBP Affinity Capture-Western physical 15598887 EP300 Affinity Capture-Western physical 15598887 CREBBP Affinity Capture-Western physical 15598887 EP300 Affinity Capture-Western physical 15598887 SIRT1 Reconstituted Complex physical 21176092 SIRT1 Affinity Capture-Western physical 21176092 SIRT1 Affinity Capture-Western physical 21176092 BCL6 Affinity Capture-MS physical 16147992