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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TCF3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000080 G1 phase of mitotic cell cycle IDA GO:0001779 natural killer cell differentiation IEA GO:0002326 B cell lineage commitment IDA GO:0002326 B cell lineage commitment NAS GO:0006351 transcription, DNA-dependent IDA GO:0006351 transcription, DNA-dependent NAS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent NAS GO:0007399 nervous system development IEA GO:0030183 B cell differentiation NAS GO:0030890 positive regulation of B cell proliferation IMP GO:0032496 response to lipopolysaccharide IEA GO:0033077 T cell differentiation in thymus IEA GO:0033152 immunoglobulin V(D)J recombination IDA GO:0042493 response to drug IEA GO:0042692 muscle cell differentiation TAS GO:0043966 histone H3 acetylation IEA GO:0043967 histone H4 acetylation IEA GO:0045666 positive regulation of neuron differentiation ISS GO:0045787 positive regulation of cell cycle IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0048468 cell development IEA GO:0048541 Peyer's patch development IEA GO:0050821 protein stabilization IEA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0051149 positive regulation of muscle cell differentiation TAS cellular_component GO:0000788 nuclear nucleosome IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus NAS GO:0005654 nucleoplasm TAS GO:0005667 transcription factor complex IDA GO:0005737 cytoplasm IDA GO:0043234 protein complex IDA molecular_function GO:0003677 DNA binding IDA GO:0003677 DNA binding NAS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity NAS GO:0003713 transcription coactivator activity IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0031435 mitogen-activated protein kinase kinase kinase binding IPI GO:0042803 protein homodimerization activity IDA GO:0043425 bHLH transcription factor binding IPI GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0046982 protein heterodimerization activity IDA GO:0046982 protein heterodimerization activity IPI GO:0046982 protein heterodimerization activity NAS GO:0070491 repressing transcription factor binding IPI GO:0070644 vitamin D response element binding IDA GO:0070888 E-box binding IDA GO:0070888 E-box binding ISS

Protein-protein interaction details for TCF3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HAND2 Two-hybrid physical 11812799 ID3 Two-hybrid physical 9525934 SKP2 Affinity Capture-Western physical 14592976 NHLH1 Two-hybrid physical 12878195 TCF3 Co-fractionation physical 12435739 EP300 Co-fractionation physical 12435739 CREBBP Co-fractionation physical 12435739 KAT2B Co-fractionation physical 12435739 CREBBP Affinity Capture-Western physical 12435739 EP300 Affinity Capture-Western physical 12435739 KAT2B Affinity Capture-Western physical 12435739 EP300 Biochemical Activity physical 12435739 CREBBP Biochemical Activity physical 12435739 KAT2B Biochemical Activity physical 12435739 KAT2B Phenotypic Enhancement genetic 12435739 EP300 Phenotypic Enhancement genetic 12435739 CREBBP Phenotypic Enhancement genetic 12435739 CALM1 Reconstituted Complex physical 10757985 LMX1A Two-hybrid physical 9199284 LMX1A Reconstituted Complex physical 9199284 ID3 Reconstituted Complex physical 9525934 TAL1 Affinity Capture-MS physical 16407974 TAL1 Affinity Capture-Western physical 16407974 TAL1 Affinity Capture-Western physical 16407974 LDB1 Affinity Capture-Western physical 16407974 CBFA2T3 Affinity Capture-Western physical 16407974 LDB1 Affinity Capture-Western physical 16407974 CBFA2T3 Affinity Capture-Western physical 16407974 TAL1 Reconstituted Complex physical 16407974 CBFA2T3 Reconstituted Complex physical 16407974 ELK3 Affinity Capture-Western physical 8918463 ELK3 Affinity Capture-Western physical 8918463 MYOD1 Reconstituted Complex physical 9184158 ID1 Two-hybrid physical 9242638 ID2 Two-hybrid physical 9242638 ID3 Two-hybrid physical 9242638 MYOD1 Two-hybrid physical 9242638 MYF5 Two-hybrid physical 9242638 MYF6 Two-hybrid physical 9242638 MYOG Two-hybrid physical 9242638 UBE2I Reconstituted Complex physical 10497239 UBE2I Two-hybrid physical 10497239 LYL1 Two-hybrid physical 8628307 LYL1 Reconstituted Complex physical 8628307 LYL1 Affinity Capture-Western physical 8628307 MYOG Two-hybrid physical 1325437 TAL1 Affinity Capture-Western physical 8159721 TAL1 Two-hybrid physical 8159721 MAPKAPK3 Two-hybrid physical 10781029 MAPKAPK3 Affinity Capture-Western physical 10781029 MAPKAPK3 Biochemical Activity physical 10781029 TWIST1 Two-hybrid physical 10749989 TWIST1 Reconstituted Complex physical 10749989 DAXX Reconstituted Complex physical 19308989 ID1 Affinity Capture-Western physical 19125693 ID1 Reconstituted Complex physical 19125693 MEN1 Reconstituted Complex physical 19074834 MEN1 Affinity Capture-Western physical 19074834 TCF4 Two-hybrid physical 20211142 VDR Affinity Capture-Western physical 16252006 BAZ1B Affinity Capture-Western physical 16252006 SMARCA4 Affinity Capture-Western physical 16252006 NCOR1 Affinity Capture-Western physical 16252006 SIN3A Affinity Capture-Western physical 16252006 HDAC2 Affinity Capture-Western physical 16252006 VDR Affinity Capture-Western physical 16252006 BAZ1B Affinity Capture-Western physical 16252006 BAZ1B Co-localization physical 16252006 VDR Co-localization physical 16252006 SMARCA4 Co-localization physical 16252006 BAZ1B Co-localization physical 16252006 VDR Reconstituted Complex physical 15934135 VDR Reconstituted Complex physical 15934135 EP300 Two-hybrid physical 15934135 PRKACA Biochemical Activity physical 15934135 EP300 Co-localization physical 15934135 VDR Co-localization physical 15934135 VDR Affinity Capture-Western physical 15934135 NCOR1 Affinity Capture-Western physical 15934135 HDAC2 Affinity Capture-Western physical 15934135 SIN3A Affinity Capture-Western physical 15934135 EP300 Affinity Capture-Western physical 15934135 RUNX1T1 Affinity Capture-Western physical 15333839 RUNX1 Affinity Capture-Western physical 15333839 VDR Affinity Capture-Western physical 17250953 HDAC2 Affinity Capture-Western physical 17250953 DNMT1 Affinity Capture-Western physical 17250953 TRIM33 Affinity Capture-MS physical 20603019 INO80E Affinity Capture-MS physical 17721549 YY1 Affinity Capture-MS physical 17721549 TAL1 Affinity Capture-MS physical 19497860 RB1 Affinity Capture-Western physical 10866689 RB1 Affinity Capture-Western physical 10866689 UBC Affinity Capture-Western physical 21119685 ASB2 Affinity Capture-Western physical 21119685