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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TFAP2A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001822 kidney development IMP GO:0003334 keratinocyte development IEA GO:0003404 optic vesicle morphogenesis ISS GO:0003409 optic cup structural organization ISS GO:0006366 transcription from RNA polymerase II promoter IDA GO:0007605 sensory perception of sound IMP GO:0008285 negative regulation of cell proliferation IDA GO:0010628 positive regulation of gene expression ISS GO:0010842 retina layer formation IEP GO:0010944 negative regulation of transcription by competitive promoter binding IDA GO:0010944 negative regulation of transcription by competitive promoter binding IMP GO:0021506 anterior neuropore closure IEA GO:0021559 trigeminal nerve development ISS GO:0021623 oculomotor nerve formation ISS GO:0030501 positive regulation of bone mineralization IDA GO:0035115 embryonic forelimb morphogenesis ISS GO:0042472 inner ear morphogenesis IMP GO:0043066 negative regulation of apoptosis IDA GO:0043525 positive regulation of neuron apoptosis IDA GO:0043588 skin development IEA GO:0045595 regulation of cell differentiation IDA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0048701 embryonic cranial skeleton morphogenesis ISS GO:0060021 palate development IMP GO:0060349 bone morphogenesis ISS GO:0061029 eyelid development in camera-type eye ISS GO:0070172 positive regulation of tooth mineralization IDA GO:0071281 cellular response to iron ion IDA GO:2000378 negative regulation of reactive oxygen species metabolic process IDA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus IMP GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005794 Golgi apparatus IDA GO:0005813 centrosome IDA GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IDA GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IDA GO:0000982 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity IDA GO:0000987 core promoter proximal region sequence-specific DNA binding IDA GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription IDA GO:0003682 chromatin binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003713 transcription coactivator activity IDA GO:0005515 protein binding IPI GO:0042803 protein homodimerization activity TAS GO:0043565 sequence-specific DNA binding IDA GO:0044212 transcription regulatory region DNA binding IDA GO:0046983 protein dimerization activity IDA

Protein-protein interaction details for TFAP2A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CITED2 Two-hybrid physical 12586840 EP300 Two-hybrid physical 12586840 TP53 Co-localization physical 12226108 APC Affinity Capture-Western physical 15331612 APC Affinity Capture-Western physical 15331612 TP53 Reconstituted Complex physical 12226108 APC Reconstituted Complex physical 15331612 CTNNB1 Affinity Capture-Western physical 15331612 TP53 Two-hybrid physical 12226108 TP53 Affinity Capture-Western physical 12226108 DEK Affinity Capture-MS physical 12595566 DEK Affinity Capture-Western physical 12595566 EP300 Affinity Capture-Western physical 12586840 CITED2 Far Western physical 12586840 CITED2 Reconstituted Complex physical 11744733 CITED4 Reconstituted Complex physical 11744733 GRB2 Affinity Capture-MS physical 12577067 MYC Affinity Capture-Western physical 7729426 MYC Reconstituted Complex physical 7729426 YBX1 Reconstituted Complex physical 9830047 UBC Affinity Capture-Western physical 16108032 YY1 Affinity Capture-Western physical 15870067 YY1 Co-localization physical 15870067 PPARG Reconstituted Complex physical 18310298 NPM1 Affinity Capture-Western physical 17318229 NPM1 Affinity Capture-Western physical 17318229 NPM1 Reconstituted Complex physical 17318229 NPM1 Co-localization physical 17318229 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572