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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TFRC (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIEA
GO:0006508proteolysisIEA
GO:0006879cellular iron ion homeostasisIEA
GO:0006879cellular iron ion homeostasisNAS
GO:0006879cellular iron ion homeostasisTAS
GO:0006897endocytosisIEA
GO:0006953acute-phase responseIEA
GO:0007568agingIEA
GO:0007584response to nutrientIEA
GO:0010033response to organic substanceIEA
GO:0010035response to inorganic substanceIEA
GO:0010039response to iron ionIEA
GO:0010042response to manganese ionIEA
GO:0030316osteoclast differentiationIEA
GO:0032526response to retinoic acidIEA
GO:0033572transferrin transportTAS
GO:0044419interspecies interaction between organismsIEA
GO:0045780positive regulation of bone resorptionIEA
GO:0046688response to copper ionIEA
GO:0055085transmembrane transportTAS
cellular_component
GO:0005576extracellular regionIDA
GO:0005739mitochondrionIEA
GO:0005768endosomeIDA
GO:0005768endosomeIEA
GO:0005886plasma membraneIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0005905coated pitIDA
GO:0009986cell surfaceIEA
GO:0016020membraneNAS
GO:0016023cytoplasmic membrane-bounded vesicleIDA
GO:0042470melanosomeIEA
GO:0048471perinuclear region of cytoplasmIEA
GO:0055038recycling endosome membraneIEA
GO:0070062extracellular vesicular exosomeIEA
molecular_function
GO:0004872receptor activityIEA
GO:0004998transferrin receptor activityIEA
GO:0004998transferrin receptor activityNAS
GO:0008233peptidase activityIEA
GO:0030544Hsp70 protein bindingIEA
GO:0051087chaperone bindingIEA

Protein-protein interaction details for TFRC (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
HFEAffinity Capture-Westernphysical9465039
HFEAffinity Capture-Westernphysical9465039
GABARAPTwo-hybridphysical11997026
GABARAPReconstituted Complexphysical11997026
GABARAPAffinity Capture-Westernphysical11997026
TFRCCo-crystal Structurephysical10531064
TFReconstituted Complexphysical11027676
HFEReconstituted Complexphysical11027676
SVIPCo-fractionationphysical17872946
PXKCo-localizationphysical20086096
RYKAffinity Capture-MSphysical21875946
BST2Co-localizationphysical20980512
HDAC5Affinity Capture-MSphysical21081666
UBCAffinity Capture-MSphysical18781797
UBCAffinity Capture-MSphysical21987572