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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TGFB3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity IEA GO:0001666 response to hypoxia IDA GO:0001701 in utero embryonic development ISS GO:0002576 platelet degranulation TAS GO:0006917 induction of apoptosis ISS GO:0007179 transforming growth factor beta receptor signaling pathway IDA GO:0007435 salivary gland morphogenesis IEP GO:0007565 female pregnancy IEA GO:0007568 aging IEA GO:0007596 blood coagulation TAS GO:0008156 negative regulation of DNA replication IMP GO:0008285 negative regulation of cell proliferation ISS GO:0009790 embryo development IEA GO:0010718 positive regulation of epithelial to mesenchymal transition IDA GO:0010718 positive regulation of epithelial to mesenchymal transition ISS GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISS GO:0010936 negative regulation of macrophage cytokine production IDA GO:0016049 cell growth IEA GO:0022601 menstrual cycle phase IEP GO:0030168 platelet activation TAS GO:0030501 positive regulation of bone mineralization IEP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA GO:0030879 mammary gland development ISS GO:0032570 response to progesterone stimulus IDA GO:0032967 positive regulation of collagen biosynthetic process IMP GO:0034616 response to laminar fluid shear stress IEA GO:0042476 odontogenesis NAS GO:0043524 negative regulation of neuron apoptosis ISS GO:0043627 response to estrogen stimulus IEA GO:0043932 ossification involved in bone remodeling IEP GO:0045216 cell-cell junction organization IDA GO:0045740 positive regulation of DNA replication IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0048286 lung alveolus development ISS GO:0048565 digestive tract development IEA GO:0048702 embryonic neurocranium morphogenesis IEA GO:0048839 inner ear development IEA GO:0050714 positive regulation of protein secretion IDA GO:0051491 positive regulation of filopodium assembly ISS GO:0051781 positive regulation of cell division IEA GO:0060021 palate development ISS GO:0060325 face morphogenesis IMP GO:0060364 frontal suture morphogenesis IEA GO:0060391 positive regulation of SMAD protein import into nucleus ISS GO:0070483 detection of hypoxia IDA GO:0071363 cellular response to growth factor stimulus IEA cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IC GO:0009986 cell surface IEA GO:0030141 stored secretory granule IEA GO:0030315 T-tubule IEA GO:0031012 extracellular matrix IDA GO:0031093 platelet alpha granule lumen TAS GO:0043025 neuronal cell body IEA molecular_function GO:0005114 type II transforming growth factor beta receptor binding IDA GO:0005114 type II transforming growth factor beta receptor binding IPI GO:0005515 protein binding IPI GO:0008083 growth factor activity IEA GO:0034713 type I transforming growth factor beta receptor binding IDA GO:0042802 identical protein binding IDA GO:0046982 protein heterodimerization activity IEA GO:0050431 transforming growth factor beta binding IDA

Protein-protein interaction details for TGFB3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID VASN Reconstituted Complex physical 15247411 TGFBR2 Reconstituted Complex physical 12729750 TGFBR2 Co-crystal Structure physical 11850637 TGFBR2 Affinity Capture-Western physical 9872992 TGFBR2 Affinity Capture-Western physical 11157754