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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TLE1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0007165 signal transduction TAS GO:0007275 multicellular organismal development TAS GO:0009887 organ morphogenesis TAS GO:0030178 negative regulation of Wnt receptor signaling pathway NAS GO:0045892 negative regulation of transcription, DNA-dependent IDA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005667 transcription factor complex IEA molecular_function GO:0001106 RNA polymerase II transcription corepressor activity IDA GO:0003682 chromatin binding IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IDA GO:0008134 transcription factor binding IPI

Protein-protein interaction details for TLE1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HES6 Two-hybrid physical 11551980 FOXA2 Two-hybrid physical 10748198 IL6ST Two-hybrid physical 12030375 AES Affinity Capture-MS physical 17353931 DLEU1 Two-hybrid physical 16169070 PFN1 Two-hybrid physical 16169070 POLB Two-hybrid physical 16169070 ARL3 Two-hybrid physical 16169070 CCL18 Two-hybrid physical 16169070 CDKN2C Two-hybrid physical 16169070 FXYD6 Two-hybrid physical 16169070 GSTM4 Two-hybrid physical 16169070 HLA-DQA1 Two-hybrid physical 16169070 CRCT1 Two-hybrid physical 16169070 POLE2 Two-hybrid physical 16169070 PEX2 Two-hybrid physical 16169070 RNF10 Two-hybrid physical 16169070 SNRPG Two-hybrid physical 16169070 CELF3 Two-hybrid physical 16169070 ARL4D Two-hybrid physical 16169070 BTBD2 Two-hybrid physical 16169070 ATN1 Two-hybrid physical 16169070 EIF2S2 Two-hybrid physical 16169070 ERH Two-hybrid physical 16169070 HSPE1 Two-hybrid physical 16169070 MPHOSPH6 Two-hybrid physical 16169070 PAFAH1B3 Two-hybrid physical 16169070 PCDHA4 Two-hybrid physical 16169070 PSMD11 Two-hybrid physical 16169070 SERPINB9 Two-hybrid physical 16169070 TK1 Two-hybrid physical 16169070 FUBP1 Two-hybrid physical 16169070 RPA2 Two-hybrid physical 16169070 SAT1 Two-hybrid physical 16169070 ZFP64 Two-hybrid physical 16169070 UTY Two-hybrid physical 9854018 KDM6A Two-hybrid physical 9854018 UTY Reconstituted Complex physical 9854018 HES6 Affinity Capture-Western physical 11551980 HES6 Two-hybrid physical 11551980 RELA Affinity Capture-Western physical 10660609 SIX3 Two-hybrid physical 12441302 SIX6 Two-hybrid physical 12441302 SIX6 Reconstituted Complex physical 12441302 SIX3 Reconstituted Complex physical 12441302 HMGB1 Reconstituted Complex physical 11748221 PRDM1 Reconstituted Complex physical 9887105 FOXA2 Reconstituted Complex physical 10748198 IL6ST Affinity Capture-Western physical 12030375 RUNX1 Two-hybrid physical 9751710 RUNX3 Two-hybrid physical 9751710 RUNX1 Far Western physical 9751710 RUNX3 Far Western physical 9751710 CTNNB1 Reconstituted Complex physical 9751710 LEF1 Reconstituted Complex physical 9751710 TLE1 Reconstituted Complex physical 9874198 TLE2 Reconstituted Complex physical 9874198 TLE2 Reconstituted Complex physical 9874198 TLE1 Two-hybrid physical 9874198 TLE2 Two-hybrid physical 9874198 UBTF Affinity Capture-Western physical 20160071 RUNX2 Affinity Capture-Western physical 20160071 RUNX2 Co-localization physical 20160071 EN1 Affinity Capture-Western physical 16571670 HDAC1 Reconstituted Complex physical 19101520 HDAC1 Affinity Capture-Western physical 19101520 NKX2-5 Two-hybrid physical 20211142 FOXA1 Two-hybrid physical 20211142 FOXA3 Two-hybrid physical 20211142 TLX2 Two-hybrid physical 20211142 MSX2 Two-hybrid physical 20211142 PAX9 Two-hybrid physical 20211142 VENTX Two-hybrid physical 20211142 TLX3 Two-hybrid physical 20211142 BARHL1 Two-hybrid physical 20211142 CUL4B Affinity Capture-MS physical 17041588 SIRT1 Two-hybrid physical 17680780 SIRT1 Affinity Capture-Western physical 17680780 NUDT21 Two-hybrid physical 21900206 GSK3B Two-hybrid physical 21900206 RAP1B Two-hybrid physical 21900206 GRB7 Two-hybrid physical 21900206 CSNK2B Two-hybrid physical 21900206 BCL2L1 Two-hybrid physical 21900206 DAZAP2 Two-hybrid physical 21900206 BID Two-hybrid physical 21900206 TK1 Two-hybrid physical 21900206 CDKN1A Two-hybrid physical 21900206 SMN1 Two-hybrid physical 21900206 RCC1 Two-hybrid physical 21900206 KIAA0408 Two-hybrid physical 21900206 ANXA7 Two-hybrid physical 21900206 TSC22D1 Two-hybrid physical 21900206 GADD45A Two-hybrid physical 21900206 HESX1 Affinity Capture-Western physical 11731482 HESX1 Reconstituted Complex physical 11731482