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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SERPING1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001869negative regulation of complement activation, lectin pathwayIDA
GO:0002576platelet degranulationTAS
GO:0006958complement activation, classical pathwayIEA
GO:0007596blood coagulationTAS
GO:0007597blood coagulation, intrinsic pathwayTAS
GO:0008015blood circulationTAS
GO:0010951negative regulation of endopeptidase activityIBA
GO:0030168platelet activationTAS
GO:0045087innate immune responseIEA
cellular_component
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIBA
GO:0005615extracellular spaceIEA
GO:0031093platelet alpha granule lumenTAS
molecular_function
GO:0004867serine-type endopeptidase inhibitor activityIDA
GO:0004867serine-type endopeptidase inhibitor activityIEA
GO:0005515protein bindingIPI
GO:0008233peptidase activityIEA
GO:0030414peptidase inhibitor activityIEA

Protein-protein interaction details for SERPING1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SELEAffinity Capture-Westernphysical14568956
SELPAffinity Capture-Westernphysical14568956
C1SCo-purificationphysical6604523
ELANEBiochemical Activityphysical6980881
F2Reconstituted Complexphysical11460008
MASP1Reconstituted Complexphysical10946292
MASP2Reconstituted Complexphysical10946292
C1RCo-fractionationphysical6282262