Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for TOP2B (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000712
resolution of meiotic recombination intermediates
IBA
GO:0000819
sister chromatid segregation
IBA
GO:0001764
neuron migration
IEA
GO:0006261
DNA-dependent DNA replication
IBA
GO:0006265
DNA topological change
IBA
GO:0006265
DNA topological change
IEA
GO:0006312
mitotic recombination
IBA
GO:0006355
regulation of transcription, DNA-dependent
IEA
GO:0007409
axonogenesis
IEA
GO:0030900
forebrain development
IEA
GO:0070683
mitotic cell cycle G2/M transition decatenation checkpoint
IBA
cellular_component
GO:0000792
heterochromatin
IDA
GO:0000795
synaptonemal complex
IBA
GO:0005634
nucleus
IDA
GO:0005634
nucleus
IEA
GO:0005654
nucleoplasm
IDA
GO:0005694
chromosome
IEA
GO:0005730
nucleolus
IDA
GO:0005737
cytoplasm
IEA
GO:0005829
cytosol
IDA
GO:0009330
DNA topoisomerase complex (ATP-hydrolyzing)
IBA
GO:0071778
WINAC complex
IDA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0003677
DNA binding
IEA
GO:0003682
chromatin binding
IDA
GO:0003918
DNA topoisomerase (ATP-hydrolyzing) activity
IBA
GO:0003918
DNA topoisomerase (ATP-hydrolyzing) activity
IEA
GO:0005080
protein kinase C binding
IPI
GO:0005524
ATP binding
IEA
GO:0008022
protein C-terminus binding
IPI
GO:0008094
DNA-dependent ATPase activity
IBA
GO:0016853
isomerase activity
IEA
GO:0019899
enzyme binding
IPI
GO:0042826
histone deacetylase binding
IPI
GO:0046982
protein heterodimerization activity
IPI
Protein-protein interaction details for TOP2B (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
TOPBP1
Two-hybrid
physical
9461304
BAZ1B
Affinity Capture-MS
physical
12837248
BAZ1B
Affinity Capture-Western
physical
12837248
HDAC1
Affinity Capture-Western
physical
11062478
HDAC2
Affinity Capture-Western
physical
11062478
MTA2
Affinity Capture-Western
physical
11062478
HDAC1
Reconstituted Complex
physical
11062478
HDAC2
Reconstituted Complex
physical
11062478
HDAC1
Reconstituted Complex
physical
11136718
HDAC1
Two-hybrid
physical
11136718
TOP2A
Reconstituted Complex
physical
8710863
TP53
Affinity Capture-Western
physical
10666337
TP53
Reconstituted Complex
physical
10666337
SUMO1
Two-hybrid
physical
10862613
SUMO1
Reconstituted Complex
physical
10862613
SUMO1
Affinity Capture-Western
physical
10862613
CD3E
Affinity Capture-Western
physical
8626450
CD3E
Reconstituted Complex
physical
8626450
CSNK2B
Two-hybrid
physical
11710515
ESR1
Affinity Capture-Western
physical
16794079
PARP1
Affinity Capture-Western
physical
16794079
SUMO2
Affinity Capture-MS
physical
19394292
SRRM1
Affinity Capture-MS
physical
16159877
PML
Affinity Capture-MS
physical
18212063
RARA
Affinity Capture-MS
physical
18212063
RARA
Reconstituted Complex
physical
18212063
USF1
Affinity Capture-Western
physical
19303849
SUMO1
Reconstituted Complex
physical
19596686
UBC
Affinity Capture-MS
physical
22178446