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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for C3 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001798
positive regulation of type IIa hypersensitivity
IEA
GO:0001970
positive regulation of activation of membrane attack complex
IEA
GO:0006954
inflammatory response
IEA
GO:0006955
immune response
TAS
GO:0006956
complement activation
IEA
GO:0006956
complement activation
TAS
GO:0006957
complement activation, alternative pathway
TAS
GO:0006958
complement activation, classical pathway
IEA
GO:0007165
signal transduction
TAS
GO:0007186
G-protein coupled receptor protein signaling pathway
TAS
GO:0010575
positive regulation vascular endothelial growth factor production
IDA
GO:0045087
innate immune response
TAS
GO:0045766
positive regulation of angiogenesis
IEA
GO:0050766
positive regulation of phagocytosis
IEA
GO:0050776
regulation of immune response
TAS
cellular_component
GO:0005576
extracellular region
IEA
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IEA
molecular_function
GO:0004866
endopeptidase inhibitor activity
IEA
GO:0005102
receptor binding
TAS
GO:0005515
protein binding
IPI
Protein-protein interaction details for C3 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
CFP
Reconstituted Complex
physical
11513971
CFI
Biochemical Activity
physical
8648130
CFP
Reconstituted Complex
physical
3421908
CFI
Reconstituted Complex
physical
9291131
CFH
Reconstituted Complex
physical
9291131
CFHR5
Reconstituted Complex
physical
11058592
CFHR3
Reconstituted Complex
physical
10622723
CFHR4
Reconstituted Complex
physical
10622723
ITGAX
Reconstituted Complex
physical
4062888
CPN1
Biochemical Activity
physical
11939578
C5
Reconstituted Complex
physical
11367533
CFH
Reconstituted Complex
physical
11367533
CFB
Reconstituted Complex
physical
11367533
UBC
Affinity Capture-MS
physical
20639865