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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for C3 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001798positive regulation of type IIa hypersensitivityIEA
GO:0001970positive regulation of activation of membrane attack complexIEA
GO:0006954inflammatory responseIEA
GO:0006955immune responseTAS
GO:0006956complement activationIEA
GO:0006956complement activationTAS
GO:0006957complement activation, alternative pathwayTAS
GO:0006958complement activation, classical pathwayIEA
GO:0007165signal transductionTAS
GO:0007186G-protein coupled receptor protein signaling pathwayTAS
GO:0010575positive regulation vascular endothelial growth factor productionIDA
GO:0045087innate immune responseTAS
GO:0045766positive regulation of angiogenesisIEA
GO:0050766positive regulation of phagocytosisIEA
GO:0050776regulation of immune responseTAS
cellular_component
GO:0005576extracellular regionIEA
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
molecular_function
GO:0004866endopeptidase inhibitor activityIEA
GO:0005102receptor bindingTAS
GO:0005515protein bindingIPI

Protein-protein interaction details for C3 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CFPReconstituted Complexphysical11513971
CFIBiochemical Activityphysical8648130
CFPReconstituted Complexphysical3421908
CFIReconstituted Complexphysical9291131
CFHReconstituted Complexphysical9291131
CFHR5Reconstituted Complexphysical11058592
CFHR3Reconstituted Complexphysical10622723
CFHR4Reconstituted Complexphysical10622723
ITGAXReconstituted Complexphysical4062888
CPN1Biochemical Activityphysical11939578
C5Reconstituted Complexphysical11367533
CFHReconstituted Complexphysical11367533
CFBReconstituted Complexphysical11367533
UBCAffinity Capture-MSphysical20639865