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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CUL5 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0006511 ubiquitin-dependent protein catabolic process IEA GO:0006970 response to osmotic stress IEA GO:0007050 cell cycle arrest TAS GO:0008283 cell proliferation TAS GO:0008285 negative regulation of cell proliferation TAS GO:0008629 induction of apoptosis by intracellular signals TAS GO:0016032 viral reproduction TAS GO:0044419 interspecies interaction between organisms IEA GO:0051480 cytosolic calcium ion homeostasis IEA GO:0070588 calcium ion transmembrane transport TAS cellular_component GO:0005624 membrane fraction IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0031461 cullin-RING ubiquitin ligase complex IEA molecular_function GO:0004872 receptor activity IEA GO:0005262 calcium channel activity TAS GO:0005515 protein binding IPI GO:0031625 ubiquitin protein ligase binding IEA

Protein-protein interaction details for CUL5 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RNF7 Two-hybrid physical 10230407 ASB3 Affinity Capture-MS physical 17353931 TCEB2 Reconstituted Complex physical 11384984 TCEB1 Reconstituted Complex physical 11384984 VHL Reconstituted Complex physical 11384984 DCUN1D1 Reconstituted Complex physical 18826954 NEDD8 Co-crystal Structure physical 18805092 RBX1 Co-crystal Structure physical 18805092 RBX1 Two-hybrid physical 10230407 ANAPC11 Two-hybrid physical 10230407 ASB4 Affinity Capture-Western physical 17636018 COPS6 Affinity Capture-MS physical 19615732 ASB2 Affinity Capture-Western physical 16325183 ASB1 Affinity Capture-Western physical 16325183 ASB6 Affinity Capture-Western physical 16325183 ASB7 Affinity Capture-Western physical 16325183 ASB12 Affinity Capture-Western physical 16325183 DIO2 Affinity Capture-Western physical 15965468 CISH Affinity Capture-MS physical 16961462 RBX1 Affinity Capture-Western physical 11861641 HSP90AA1 Affinity Capture-MS physical 19933325 HSPA4 Affinity Capture-MS physical 19933325 HSP90AA1 Affinity Capture-Western physical 19933325 HSPA4 Affinity Capture-Western physical 19933325 HSPA4 Affinity Capture-Western physical 19933325 ERBB2 Affinity Capture-Western physical 19933325 COMMD1 Reconstituted Complex physical 21778237 COMMD1 Reconstituted Complex physical 21778237 NEDD8 Affinity Capture-Western physical 20847044 DNMT3B Affinity Capture-Western physical 20847044 NOS2 Affinity Capture-Western physical 21199876 TCEB1 Affinity Capture-Western physical 21199876 SOCS2 Affinity Capture-Western physical 21980433 NEDD8 Affinity Capture-MS physical 18274552 ASB9 Affinity Capture-MS physical 20302626 ASB2 Affinity Capture-Western physical 21119685 ASB2 Affinity Capture-Western physical 21119685 TCEB2 Affinity Capture-Western physical 21119685 SKP2 Affinity Capture-Western physical 21119685 NEDD8 Affinity Capture-Western physical 21119685 SOCS6 Affinity Capture-Western physical 21030588 TCEB1 Reconstituted Complex physical 20463065 TCEB2 Reconstituted Complex physical 20463065 CAND1 Affinity Capture-MS physical 21249194 CAND1 Affinity Capture-Western physical 21249194 UBC Affinity Capture-MS physical 21987572 NOS2 Biochemical Activity physical 20603330