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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CALR (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0002474 antigen processing and presentation of peptide antigen via MHC class I TAS GO:0002502 peptide antigen assembly with MHC class I protein complex IEA GO:0002502 peptide antigen assembly with MHC class I protein complex ISS GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006457 protein folding IEA GO:0006457 protein folding TAS GO:0006611 protein export from nucleus IDA GO:0006874 cellular calcium ion homeostasis TAS GO:0007050 cell cycle arrest IGI GO:0007283 spermatogenesis IEA GO:0008284 positive regulation of cell proliferation IGI GO:0017148 negative regulation of translation IEA GO:0017148 negative regulation of translation ISS GO:0017148 negative regulation of translation TAS GO:0018279 protein N-linked glycosylation via asparagine TAS GO:0022417 protein maturation by protein folding TAS GO:0030866 cortical actin cytoskeleton organization IEA GO:0032355 response to estradiol stimulus IEA GO:0033144 negative regulation of steroid hormone receptor signaling pathway IDA GO:0033574 response to testosterone stimulus IEA GO:0034504 protein localization to nucleus IDA GO:0040020 regulation of meiosis IEA GO:0042493 response to drug IEA GO:0042921 glucocorticoid receptor signaling pathway TAS GO:0042981 regulation of apoptosis TAS GO:0043687 post-translational protein modification TAS GO:0044267 cellular protein metabolic process TAS GO:0045665 negative regulation of neuron differentiation IDA GO:0045740 positive regulation of DNA replication IGI GO:0045787 positive regulation of cell cycle IEA GO:0045787 positive regulation of cell cycle IGI GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0048387 negative regulation of retinoic acid receptor signaling pathway IDA GO:0050766 positive regulation of phagocytosis IEA GO:0050766 positive regulation of phagocytosis ISS GO:0050821 protein stabilization IEA GO:0050821 protein stabilization ISS GO:0050821 protein stabilization TAS GO:0051208 sequestering of calcium ion TAS GO:0055007 cardiac muscle cell differentiation IEA GO:0071285 cellular response to lithium ion IEA GO:0071310 cellular response to organic substance IEA GO:0090398 cellular senescence IEA GO:0090398 cellular senescence IGI cellular_component GO:0001669 acrosomal vesicle IEA GO:0005576 extracellular region IEA GO:0005578 proteinaceous extracellular matrix IEA GO:0005615 extracellular space IDA GO:0005615 extracellular space IEA GO:0005622 intracellular TAS GO:0005625 soluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005783 endoplasmic reticulum TAS GO:0005788 endoplasmic reticulum lumen IDA GO:0005788 endoplasmic reticulum lumen TAS GO:0005792 microsome IEA GO:0005794 Golgi apparatus IEA GO:0005829 cytosol IDA GO:0005844 polysome IEA GO:0005844 polysome ISS GO:0009897 external side of plasma membrane IEA GO:0009986 cell surface TAS GO:0016529 sarcoplasmic reticulum IEA GO:0031012 extracellular matrix IEA GO:0042824 MHC class I peptide loading complex IEA GO:0042824 MHC class I peptide loading complex ISS GO:0048471 perinuclear region of cytoplasm IDA GO:0048471 perinuclear region of cytoplasm IEA GO:0071556 integral to lumenal side of endoplasmic reticulum membrane TAS molecular_function GO:0001849 complement component C1q binding TAS GO:0003677 DNA binding NAS GO:0003729 mRNA binding IDA GO:0003729 mRNA binding IEA GO:0005178 integrin binding IPI GO:0005506 iron ion binding IEA GO:0005509 calcium ion binding IEA GO:0005509 calcium ion binding ISS GO:0005509 calcium ion binding TAS GO:0005515 protein binding IPI GO:0005529 sugar binding IEA GO:0008270 zinc ion binding TAS GO:0030246 carbohydrate binding TAS GO:0031625 ubiquitin protein ligase binding IPI GO:0042277 peptide binding IEA GO:0042562 hormone binding IEA GO:0044183 protein binding involved in protein folding TAS GO:0050681 androgen receptor binding IDA GO:0051082 unfolded protein binding IEA GO:0051082 unfolded protein binding TAS GO:0051087 chaperone binding TAS

Protein-protein interaction details for CALR (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CD40 Affinity Capture-MS physical 17353931 ELF3 Affinity Capture-MS physical 17353931 EPB41 Affinity Capture-MS physical 17353931 LRP1 Affinity Capture-Western physical 14980518 PLAT Reconstituted Complex physical 9359841 MBL2 Reconstituted Complex physical 8062452 PDIA3 Affinity Capture-Western physical 10436013 CANX Affinity Capture-Western physical 10436013 PDIA3 Co-purification physical 10436013 PDIA3 Reconstituted Complex physical 10436013 PDIA3 Reconstituted Complex physical 10436013 PRF1 Affinity Capture-Western physical 9671507 PRF1 Reconstituted Complex physical 9671507 FGB Affinity Capture-MS physical 7592883 APP Affinity Capture-Western physical 11378243 CD1D Affinity Capture-Western physical 12239218 APOB Affinity Capture-Western physical 10513896 TAPBP Affinity Capture-Western physical 8769474 VWF Affinity Capture-Western physical 10887119 AR Reconstituted Complex physical 8107809 F5 Affinity Capture-Western physical 9525969 NR3C1 Reconstituted Complex physical 8107808 TF Reconstituted Complex physical 9312001 SLC6A4 Reconstituted Complex physical 10364189 NKX2-1 Two-hybrid physical 9988700 NKX2-1 Reconstituted Complex physical 9988700 SLC2A1 Reconstituted Complex physical 8662691 H2AFX Affinity Capture-MS physical 16522924 H2AFX Affinity Capture-Western physical 16522924 H2AFX Affinity Capture-MS physical 20000738 H2AFX Affinity Capture-Western physical 20000738 PSMA3 Affinity Capture-MS physical 22079093 C1orf103 Two-hybrid physical 21900206 SMARCB1 Two-hybrid physical 21900206 MAPK6 Two-hybrid physical 21900206 ITGAV Affinity Capture-Western physical 12196561 ITGA5 Affinity Capture-Western physical 12196561