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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SHARPIN (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007005mitochondrion organizationIEA
GO:0007420brain developmentIEA
GO:0008544epidermis developmentIEA
GO:0010803regulation of tumor necrosis factor-mediated signaling pathwayIDA
GO:0030262apoptotic nuclear changeIEA
GO:0031424keratinizationIEA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0050728negative regulation of inflammatory responseISS
GO:0051260protein homooligomerizationIEA
GO:0097039protein linear polyubiquitinationIDA
GO:2000348regulation of CD40 signaling pathwayIDA
cellular_component
GO:0005622intracellularIEA
GO:0005737cytoplasmIEA
GO:0005829cytosolIDA
GO:0014069postsynaptic densityIEA
GO:0030425dendriteIEA
GO:0071797LUBAC complexIDA
molecular_function
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0031593polyubiquitin bindingIDA
GO:0042802identical protein bindingIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for SHARPIN (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SHANK1Two-hybridphysical11178875
SharpinAffinity Capture-Westernphysical11178875
SHANK1Affinity Capture-Westernphysical11178875
UBCAffinity Capture-MSphysical21987572