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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SMC1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000070 mitotic sister chromatid segregation TAS GO:0000075 cell cycle checkpoint IDA GO:0000087 M phase of mitotic cell cycle TAS GO:0000236 mitotic prometaphase TAS GO:0000278 mitotic cell cycle TAS GO:0000398 nuclear mRNA splicing, via spliceosome TAS GO:0006281 DNA repair TAS GO:0007052 mitotic spindle organization TAS GO:0007062 sister chromatid cohesion IMP GO:0007064 mitotic sister chromatid cohesion TAS GO:0007091 mitotic metaphase/anaphase transition TAS GO:0007126 meiosis ISS GO:0008380 RNA splicing TAS GO:0009314 response to radiation IEP GO:0010467 gene expression TAS GO:0032876 negative regulation of DNA endoreduplication IMP GO:0042770 signal transduction in response to DNA damage IDA GO:0051301 cell division IEA cellular_component GO:0000776 kinetochore IDA GO:0000777 condensed chromosome kinetochore IEA GO:0000794 condensed nuclear chromosome TAS GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005694 chromosome IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0008280 cohesin core heterodimer TAS GO:0030893 meiotic cohesin complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003682 chromatin binding IDA GO:0003777 microtubule motor activity NAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for SMC1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID STYXL1 Affinity Capture-MS physical 17353931 CASP4 Affinity Capture-MS physical 17353931 CDK4 Affinity Capture-MS physical 17353931 ATM Affinity Capture-Western physical 11877376 ATM Reconstituted Complex physical 11877376 SMC3 Affinity Capture-Western physical 11877376 MSH6 Reconstituted Complex physical 14657349 CHTF18 Affinity Capture-Western physical 12930902 REC8 Affinity Capture-Western physical 12759374 SYCP3 Affinity Capture-Western physical 12759374 SMC3 Affinity Capture-Western physical 12759374 SMC3 Affinity Capture-Western physical 12759374 SMARCA5 Co-purification physical 12198550 SMC3 Affinity Capture-Western physical 9789013 SMC3 Affinity Capture-Western physical 11590136 RAD21 Affinity Capture-Western physical 11590136 NUMA1 Affinity Capture-Western physical 11590136 STAG1 Co-purification physical 11076961 STAG3 Affinity Capture-Western physical 11483963 RAE1 Affinity Capture-Western physical 18832153 SMC1A Affinity Capture-Western physical 18832153 RAE1 Affinity Capture-Western physical 18832153 USP13 Affinity Capture-MS physical 19615732 USP32 Affinity Capture-MS physical 19615732 MLH1 Affinity Capture-MS physical 17148452 ATRX Affinity Capture-Western physical 20159591 AIRE Affinity Capture-MS physical 20085707 AIRE Affinity Capture-Western physical 20085707 RAD21 Co-localization physical 19308699 ATG2A Affinity Capture-MS physical 20562859 ATG4C Affinity Capture-MS physical 20562859 BECN1 Affinity Capture-MS physical 20562859 CAMKK2 Affinity Capture-MS physical 20562859 PRKAA2 Affinity Capture-MS physical 20562859 MGMT Affinity Capture-MS physical 16226712 SRRM1 Affinity Capture-Western physical 16159877 SRRM1 Co-fractionation physical 16159877 SRRM1 Affinity Capture-MS physical 16159877 RPGR Affinity Capture-Western physical 16043481 RPGR Reconstituted Complex physical 16043481 RPGR Reconstituted Complex physical 16043481 ATR Affinity Capture-Western physical 15640246 PHF1 Affinity Capture-Western physical 18385154 PHF1 Affinity Capture-MS physical 18385154 CTCF Affinity Capture-Western physical 18219272 PAXIP1 Affinity Capture-MS physical 17925232 THRA Affinity Capture-MS physical 17242407 THRB Affinity Capture-MS physical 17242407 KDM1B Affinity Capture-Western physical 20670891 EHMT2 Affinity Capture-Western physical 20670891 EHMT2 Affinity Capture-Western physical 20670891 SSU72 Affinity Capture-Western physical 20818333 STAG1 Affinity Capture-MS physical 17113138 STAG2 Affinity Capture-MS physical 17113138 SMC3 Affinity Capture-MS physical 17113138 PDS5A Affinity Capture-MS physical 17113138 PDS5B Affinity Capture-MS physical 17113138 WFDC5 Affinity Capture-MS physical 17113138 WFDC5 Affinity Capture-Western physical 17112726 STAG2 Affinity Capture-Western physical 17112726 RAD21 Affinity Capture-Western physical 17112726 PDS5B Affinity Capture-Western physical 17112726 PDS5A Affinity Capture-Western physical 17112726 WFDC5 Affinity Capture-Western physical 17112726 STAG1 Reconstituted Complex physical 17112726 BRCA1 Affinity Capture-Western physical 11877377 ATM Biochemical Activity physical 11877377 HDAC5 Affinity Capture-MS physical 21081666 SMC3 Affinity Capture-MS physical 17349791 SMC3 Affinity Capture-Western physical 17349791 WAPAL Affinity Capture-MS physical 20360068 BARD1 Co-purification physical 16391231 SUMO1 Reconstituted Complex physical 19596686 UBC Affinity Capture-MS physical 22178446 PDS5A Affinity Capture-Western physical 15855230 PDS5B Affinity Capture-Western physical 15855230 UBC Affinity Capture-MS physical 18781797