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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IKBKG (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0001782 B cell homeostasis IEA GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006917 induction of apoptosis TAS GO:0006954 inflammatory response TAS GO:0006955 immune response TAS GO:0006974 response to DNA damage stimulus IDA GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0007250 activation of NF-kappaB-inducing kinase activity IEA GO:0007254 JNK cascade TAS GO:0008063 Toll signaling pathway TAS GO:0009615 response to virus TAS GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade TAS GO:0044419 interspecies interaction between organisms IEA GO:0045087 innate immune response TAS GO:0050852 T cell receptor signaling pathway NAS GO:0050852 T cell receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051403 stress-activated MAPK cascade TAS GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol IEA GO:0005829 cytosol TAS GO:0008385 IkappaB kinase complex TAS GO:0044444 cytoplasmic part IDA molecular_function GO:0004871 signal transducer activity TAS GO:0005515 protein binding IPI GO:0019904 protein domain specific binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for IKBKG (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NFKB2 Affinity Capture-MS physical 14743216 NFKB1 Affinity Capture-MS physical 14743216 CDC37 Affinity Capture-MS physical 14743216 ATG16L1 Affinity Capture-MS physical 14743216 HSP90AA2 Affinity Capture-MS physical 14743216 TBK1 Affinity Capture-MS physical 14743216 ZFAND5 Affinity Capture-Western physical 14754897 TRPC4AP Affinity Capture-Western physical 14585990 PPM1B Affinity Capture-Western physical 14585847 PPM1B Affinity Capture-Western physical 14585847 HSPA1A Reconstituted Complex physical 11877453 CHUK Reconstituted Complex physical 11877453 COPS3 Affinity Capture-Western physical 11418127 IKBKB Co-purification physical 11864612 CDC37 Affinity Capture-Western physical 11864612 IKBKB Affinity Capture-Western physical 11864612 CHUK Affinity Capture-Western physical 11864612 MAP3K14 Affinity Capture-Western physical 9927690 TNFRSF1A Affinity Capture-Western physical 10755617 TNFAIP3 Two-hybrid physical 10755617 TNFAIP3 Affinity Capture-Western physical 10755617 TANK Two-hybrid physical 12133833 TANK Reconstituted Complex physical 12133833 TANK Affinity Capture-Western physical 12133833 IKBKB Affinity Capture-Western physical 12133833 RIPK2 Affinity Capture-Western physical 10880512 RIPK1 Affinity Capture-Western physical 10880512 NCOA3 Affinity Capture-MS physical 11971985 NCOA3 Co-fractionation physical 11971985 NCOA3 Affinity Capture-Western physical 11971985 IKBKB Affinity Capture-Western physical 11971985 NCOA3 Reconstituted Complex physical 11971985 CARD8 Affinity Capture-Western physical 11551959 TRAF3IP2 Affinity Capture-Western physical 10962033 TRAF3IP2 Affinity Capture-Western physical 10962024 CHUK Co-purification physical 11057907 IKBKB Co-purification physical 11057907 TRAF6 Reconstituted Complex physical 18617513 IRAK1 Reconstituted Complex physical 18347055 IRAK1 Affinity Capture-Western physical 18347055 BCL10 Reconstituted Complex physical 18287044 BCL10 Affinity Capture-Western physical 18287044 UBC Reconstituted Complex physical 18216269 CHUK Affinity Capture-Western physical 18207244 IKBKB Affinity Capture-Western physical 18207244 IRAK1 Reconstituted Complex physical 18180283 IRAK1 Affinity Capture-Western physical 18180283 TRAF6 Reconstituted Complex physical 18180283 CNTN2 Affinity Capture-Western physical 17942533 TUBG1 Affinity Capture-Western physical 17891179 CNTN2 Affinity Capture-Western physical 17891179 CNTN2 Affinity Capture-Western physical 17891179 UBC Affinity Capture-Western physical 17135271 TRAF6 Biochemical Activity physical 17135271 CETN3 Reconstituted Complex physical 20098747 SYT1 Reconstituted Complex physical 20098747 CPNE2 Reconstituted Complex physical 20098747 HPCAL1 Reconstituted Complex physical 20098747 MYL5 Reconstituted Complex physical 20098747 CALB1 Reconstituted Complex physical 20098747 TTYH2 Reconstituted Complex physical 20098747 TPT1 Reconstituted Complex physical 20098747 H1F0 Reconstituted Complex physical 20098747 MCM7 Reconstituted Complex physical 20098747 CNOT7 Reconstituted Complex physical 20098747 ADAP2 Reconstituted Complex physical 20098747 TBC1D7 Reconstituted Complex physical 20098747 GNGT1 Reconstituted Complex physical 20098747 SEPT9 Reconstituted Complex physical 20098747 IKBKB Reconstituted Complex physical 20098747 PRKCB Reconstituted Complex physical 20098747 TBK1 Reconstituted Complex physical 20098747 CHUK Reconstituted Complex physical 20098747 LCK Reconstituted Complex physical 20098747 CDK2 Reconstituted Complex physical 20098747 FLT3 Reconstituted Complex physical 20098747 FGR Reconstituted Complex physical 20098747 STK25 Reconstituted Complex physical 20098747 PIM2 Reconstituted Complex physical 20098747 EPHA4 Reconstituted Complex physical 20098747 TEK Reconstituted Complex physical 20098747 JAK2 Reconstituted Complex physical 20098747 TEC Reconstituted Complex physical 20098747 FLT4 Reconstituted Complex physical 20098747 RPS6KB2 Reconstituted Complex physical 20098747 GRK4 Reconstituted Complex physical 20098747 PRKD3 Reconstituted Complex physical 20098747 MAP3K2 Reconstituted Complex physical 20098747 AKT1 Reconstituted Complex physical 20098747 SGK1 Reconstituted Complex physical 20098747 ITK Reconstituted Complex physical 20098747 TYRO3 Reconstituted Complex physical 20098747 MERTK Reconstituted Complex physical 20098747 ALK Reconstituted Complex physical 20098747 JAK3 Reconstituted Complex physical 20098747 RET Reconstituted Complex physical 20098747 ROR2 Reconstituted Complex physical 20098747 SRPK1 Reconstituted Complex physical 20098747 PCK1 Reconstituted Complex physical 20098747 ROS1 Reconstituted Complex physical 20098747 DAPK1 Reconstituted Complex physical 20098747 CUEDC1 Reconstituted Complex physical 20098747 RNF7 Reconstituted Complex physical 20098747 RBCK1 Reconstituted Complex physical 20098747 PSMA3 Reconstituted Complex physical 20098747 WDR5 Reconstituted Complex physical 20098747 LZIC Reconstituted Complex physical 20098747 ARL6IP4 Reconstituted Complex physical 20098747 PDCL Reconstituted Complex physical 20098747 PFDN5 Reconstituted Complex physical 20098747 LPXN Reconstituted Complex physical 20098747 METTL11A Reconstituted Complex physical 20098747 GADD45G Reconstituted Complex physical 20098747 LUC7L2 Reconstituted Complex physical 20098747 GADD45GIP1 Reconstituted Complex physical 20098747 PHF7 Reconstituted Complex physical 20098747 SCLT1 Reconstituted Complex physical 20098747 NAP1L5 Reconstituted Complex physical 20098747 TRIM41 Reconstituted Complex physical 20098747 APRT Reconstituted Complex physical 20098747 KRT8 Reconstituted Complex physical 20098747 C19orf57 Reconstituted Complex physical 20098747 NECAB3 Reconstituted Complex physical 20098747 MCM10 Reconstituted Complex physical 20098747 RPAP3 Reconstituted Complex physical 20098747 RBM34 Reconstituted Complex physical 20098747 NHP2 Reconstituted Complex physical 20098747 EIF1AX Reconstituted Complex physical 20098747 DDX19B Reconstituted Complex physical 20098747 RBM8A Reconstituted Complex physical 20098747 RPS12 Reconstituted Complex physical 20098747 RPL41 Reconstituted Complex physical 20098747 SIP1 Reconstituted Complex physical 20098747 MLLT6 Reconstituted Complex physical 20098747 TCEANC Reconstituted Complex physical 20098747 TCP10L Reconstituted Complex physical 20098747 TCP11L1 Reconstituted Complex physical 20098747 LMCD1 Reconstituted Complex physical 20098747 NRBF2 Reconstituted Complex physical 20098747 FAM128A Reconstituted Complex physical 20098747 TSLP Reconstituted Complex physical 20098747 DNAJC8 Reconstituted Complex physical 20098747 FRMD8 Reconstituted Complex physical 20098747 C19orf12 Reconstituted Complex physical 20098747 TCP11 Reconstituted Complex physical 20098747 HBZ Reconstituted Complex physical 20098747 C4orf43 Reconstituted Complex physical 20098747 VAMP3 Reconstituted Complex physical 20098747 KIR3DX1 Reconstituted Complex physical 20098747 ARGLU1 Reconstituted Complex physical 20098747 GYG2 Reconstituted Complex physical 20098747 PNMAL1 Reconstituted Complex physical 20098747 LGALS2 Reconstituted Complex physical 20098747 ODAM Reconstituted Complex physical 20098747 AMMECR1L Reconstituted Complex physical 20098747 PLEKHJ1 Reconstituted Complex physical 20098747 AVPI1 Reconstituted Complex physical 20098747 SENP2 Reconstituted Complex physical 20098747 ACBD6 Reconstituted Complex physical 20098747 KIAA1598 Reconstituted Complex physical 20098747 NRARP Reconstituted Complex physical 20098747 ARPP19 Reconstituted Complex physical 20098747 IKBKB Affinity Capture-Western physical 20098747 CALB1 Affinity Capture-Western physical 20098747 CDK2 Affinity Capture-Western physical 20098747 RNF7 Affinity Capture-Western physical 20098747 SENP2 Affinity Capture-Western physical 20098747 SYT1 Affinity Capture-Western physical 20098747 IKBKB Two-hybrid physical 20098747 CALB1 Two-hybrid physical 20098747 CDK2 Two-hybrid physical 20098747 RNF7 Two-hybrid physical 20098747 SENP2 Two-hybrid physical 20098747 SYT1 Two-hybrid physical 20098747 RIPK1 Affinity Capture-Western physical 16543241 CNTN2 Affinity Capture-Western physical 16424386 LRDD Affinity Capture-Western physical 16360037 SUMO1 Affinity Capture-Western physical 16360037 UBC Affinity Capture-Western physical 16360037 PRKCQ Affinity Capture-Western physical 15802604 IKBKB Affinity Capture-Western physical 15802604 EEF1A1 Two-hybrid physical 20211142 GTF2E1 Two-hybrid physical 20211142 HCLS1 Two-hybrid physical 20211142 ID1 Two-hybrid physical 20211142 ID3 Two-hybrid physical 20211142 PA2G4 Two-hybrid physical 20211142 POLR2B Two-hybrid physical 20211142 POLR2D Two-hybrid physical 20211142 POLR2E Two-hybrid physical 20211142 RNF4 Two-hybrid physical 20211142 SUPT5H Two-hybrid physical 20211142 TAF7 Two-hybrid physical 20211142 TARBP2 Two-hybrid physical 20211142 LZTR1 Two-hybrid physical 20211142 AIP Two-hybrid physical 20211142 MED7 Two-hybrid physical 20211142 WWP1 Two-hybrid physical 20211142 TRIM31 Two-hybrid physical 20211142 POLR3A Two-hybrid physical 20211142 SNW1 Two-hybrid physical 20211142 TRIM29 Two-hybrid physical 20211142 ZZZ3 Two-hybrid physical 20211142 ZBTB3 Two-hybrid physical 20211142 UBC Affinity Capture-Western physical 14748687 SUMO1 Affinity Capture-Western physical 14651848 UBC Affinity Capture-Western physical 14651848 CYLD Two-hybrid physical 12917691 CYLD Two-hybrid physical 12917691 CYLD Affinity Capture-Western physical 12917691 CYLD Biochemical Activity physical 12917691 CYLD Affinity Capture-Western physical 12917690 CYLD Reconstituted Complex physical 12917689 UBC Affinity Capture-Western physical 12867425 UBC Affinity Capture-Western physical 12867425 BIRC2 Affinity Capture-Western physical 12867425 TRAF2 Affinity Capture-Western physical 12867425 PLK1 Affinity Capture-Western physical 20484576 TANK Affinity Capture-Western physical 20484576 TANK Affinity Capture-Western physical 20484576 PLK1 Affinity Capture-Western physical 20484576 MAP3K7 Affinity Capture-Western physical 19531477 CHUK Affinity Capture-Western physical 9751060 IKBKB Affinity Capture-Western physical 9751060 CHUK Affinity Capture-Western physical 9751060 CYLD Affinity Capture-Western physical 16627981 IRAK1 Affinity Capture-Western physical 17997719 TNF Affinity Capture-MS physical 20005846 TNF Affinity Capture-Western physical 16603398 IKBKB Affinity Capture-Western physical 16603398 RIPK1 Affinity Capture-Western physical 16603398 UBC Affinity Capture-Western physical 16603398 UBC Affinity Capture-Western physical 16603398 BCL10 Affinity Capture-Western physical 19897484 UBC Affinity Capture-Western physical 19897484 UBC Affinity Capture-Western physical 17314283 PARK2 Affinity Capture-Western physical 17314283 PARK2 Affinity Capture-Western physical 17314283 UBC Reconstituted Complex physical 21113135 UBC Affinity Capture-Western physical 21113135 RIPK1 Affinity Capture-Western physical 21113135 UBC Affinity Capture-Western physical 19820708 IKBKB Affinity Capture-Western physical 19820708 UBC Affinity Capture-Western physical 20010814 UBC Reconstituted Complex physical 20010814 TNIP1 Affinity Capture-Western physical 20010814 CUL1 Affinity Capture-Western physical 19656241 BTRC Affinity Capture-Western physical 19656241 IKBKB Affinity Capture-Western physical 19656241 RIPK2 Affinity Capture-Western physical 18079694 CHUK Affinity Capture-Western physical 18079694 NFKBIA Biochemical Activity physical 21896478 MIB2 Affinity Capture-Western physical 21896478 UBC Affinity Capture-Western physical 21896478 RPAP3 Affinity Capture-Western physical 21184742 UBC Affinity Capture-Western physical 21184742 IKBKB Affinity Capture-Western physical 20932476 ERC1 Affinity Capture-Western physical 20932476 CDKN1A Two-hybrid physical 19609363 IRAK1 Affinity Capture-Western physical 21220427 UBC Affinity Capture-Western physical 21220427 RUSC1 Affinity Capture-Western physical 19365808 IKBKB Affinity Capture-Western physical 19365808 UBC Affinity Capture-Western physical 19365808 NCOA3 Affinity Capture-MS physical 16051665 UBC Reconstituted Complex physical 20959607 CNTN2 Affinity Capture-Western physical 19064727 UBC Reconstituted Complex physical 19675569 TRAF6 Affinity Capture-Western physical 20529958 TRAF6 Reconstituted Complex physical 20529958 UBC Affinity Capture-Western physical 20932475 BIRC2 Affinity Capture-Western physical 20932475 SUMO1 Affinity Capture-Western physical 20932475 BIRC2 Affinity Capture-Western physical 20932475 TRAF6 Affinity Capture-Western physical 20932475 MALT1 Affinity Capture-Western physical 19494296 MYC Affinity Capture-Western physical 20970423 UBC Affinity Capture-Western physical 20164171 TRIM40 Affinity Capture-Western physical 21474709 TRIM40 Affinity Capture-Western physical 21474709 NEDD8 Affinity Capture-Western physical 21474709 MAVS Affinity Capture-Western physical 20161788 CHUK Affinity Capture-Western physical 19815509 IKBKB Affinity Capture-Western physical 19815509 IKBKB Affinity Capture-Western physical 22099304 RIPK1 Affinity Capture-Western physical 22099304 TNFAIP3 Affinity Capture-Western physical 22099304 TNFAIP3 Reconstituted Complex physical 22099304 CHUK Affinity Capture-MS physical 21903422 IKBKB Affinity Capture-MS physical 21903422 MAVS Affinity Capture-MS physical 21903422 TBK1 Affinity Capture-MS physical 21903422 CHUK Affinity Capture-MS physical 21903422 IKBKB Affinity Capture-MS physical 21903422 MAVS Reconstituted Complex physical 21903422 NFKBIA Affinity Capture-Western physical 22081069 UBC Affinity Capture-Western physical 20837477 AKT1 Affinity Capture-Western physical 20837477 UBC Affinity Capture-MS physical 22118674 USP7 Affinity Capture-Western physical 18952891 UBC Affinity Capture-Western physical 18952891 UBC Affinity Capture-Western physical 15620648 NLRX1 Affinity Capture-Western physical 21703539 CHUK Affinity Capture-Western physical 21703539 UBC Affinity Capture-Western physical 21513986