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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CBX4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIMP
GO:0006916anti-apoptosisTAS
GO:0016568chromatin modificationIEA
GO:0045892negative regulation of transcription, DNA-dependentIDA
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005794Golgi apparatusIDA
GO:0031519PcG protein complexIDA
GO:0035102PRC1 complexIDA
molecular_function
GO:0003682chromatin bindingIEA
GO:0003714transcription corepressor activityTAS
GO:0003727single-stranded RNA bindingIEA
GO:0005515protein bindingIPI
GO:0019899enzyme bindingIPI
GO:0035064methylated histone residue bindingIEA
GO:0051219phosphoprotein bindingIEA

Protein-protein interaction details for CBX4 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
RING1Two-hybridphysical9858531
MLLReconstituted Complexphysical12829790
CTBP1Reconstituted Complexphysical12829790
MLLReconstituted Complexphysical12829790
BMI1Reconstituted Complexphysical12829790
CTBP1Biochemical Activityphysical12679040
RING1Two-hybridphysical9199346
RING1Affinity Capture-Westernphysical9199346
RING1Affinity Capture-Westernphysical9199346
BMI1Affinity Capture-Westernphysical9199346
PHC1Affinity Capture-Westernphysical9199346
BMI1Affinity Capture-Westernphysical9199346
PHC1Affinity Capture-Westernphysical9199346
RING1Reconstituted Complexphysical9858531
RB1Phenotypic Enhancementgenetic11583618
CTBP1Affinity Capture-Westernphysical11583618
RB1Affinity Capture-Westernphysical11583618
RNF2Two-hybridphysical16169070
CTBP1Two-hybridphysical9858600
CTBP2Two-hybridphysical9858600
CTBP2Affinity Capture-Westernphysical9858600
CTBP2Affinity Capture-Westernphysical9858600
BMI1Affinity Capture-Westernphysical18453536
MBD1Reconstituted Complexphysical17428788
MBD1Affinity Capture-Westernphysical17428788
KDM5BAffinity Capture-MSphysical19336002
KDM5BAffinity Capture-Westernphysical19336002
KDM5BReconstituted Complexphysical19336002
KDM5BReconstituted Complexphysical19336002
KDM5BAffinity Capture-Westernphysical19336002
PCGF2Affinity Capture-MSphysical19636380
BMI1Affinity Capture-MSphysical19636380
SUV39H1Two-hybridphysical12101246
SUV39H1Reconstituted Complexphysical12101246
SUV39H1Affinity Capture-Westernphysical12101246
SUV39H1Affinity Capture-Westernphysical12101246
DNMT3AReconstituted Complexphysical17439403
DNMT3AAffinity Capture-Westernphysical17439403
DNMT3AAffinity Capture-Westernphysical17439403
SATB1Two-hybridphysical20351170
CTBP1Affinity Capture-Westernphysical20361981
HIST3H3Biochemical Activityphysical12700765
UBCAffinity Capture-MSphysical18781797
SNCAAffinity Capture-Westernphysical21256122