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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Shc1 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeISO
GO:0000187activation of MAPK activityIMP
GO:0000187activation of MAPK activityISO
GO:0001525angiogenesisIEA
GO:0001525angiogenesisISO
GO:0001666response to hypoxiaIEP
GO:0007265Ras protein signal transductionIEA
GO:0007507heart developmentIEA
GO:0007507heart developmentISO
GO:0007568agingIPI
GO:0008286insulin receptor signaling pathwayIDA
GO:0008286insulin receptor signaling pathwayIMP
GO:0009636response to toxinIEP
GO:0014070response to organic cyclic compoundIEP
GO:0016337cell-cell adhesionIEA
GO:0016337cell-cell adhesionISO
GO:0030036actin cytoskeleton organizationIMP
GO:0030182neuron differentiationIMP
GO:0031100organ regenerationIEP
GO:0031175neuron projection developmentIMP
GO:0031532actin cytoskeleton reorganizationIEA
GO:0031532actin cytoskeleton reorganizationISO
GO:0032868response to insulin stimulusIEP
GO:0035094response to nicotineIEP
GO:0035556intracellular signal transductionIEA
GO:0040008regulation of growthIEA
GO:0042542response to hydrogen peroxideIEP
GO:0045740positive regulation of DNA replicationIMP
GO:0045907positive regulation of vasoconstrictionIMP
GO:0048661positive regulation of smooth muscle cell proliferationIMP
GO:0051384response to glucocorticoid stimulusIEP
cellular_component
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolIEA
GO:0005886plasma membraneIDA
GO:0005886plasma membraneISO
GO:0010008endosome membraneIDA
GO:0070435Shc-EGFR complexIDA
molecular_function
GO:0001784phosphotyrosine bindingIPI
GO:0005154epidermal growth factor receptor bindingIPI
GO:0005158insulin receptor bindingIEA
GO:0005158insulin receptor bindingISO
GO:0005159insulin-like growth factor receptor bindingIEA
GO:0005159insulin-like growth factor receptor bindingISO
GO:0005515protein bindingIPI
GO:0032403protein complex bindingIPI
GO:0046875ephrin receptor bindingISO
GO:0051219phosphoprotein bindingIPI

Protein-protein interaction details for Shc1 (Rattus norvegicus)
(Information is obtained from BioGRID)
Interacting proteinExperimentTypePubMed ID
Grb2Affinity Capture-Westernphysical12167719