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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNFSF11 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001503 ossification IEA GO:0002548 monocyte chemotaxis IDA GO:0006950 response to stress IEA GO:0006955 immune response NAS GO:0007257 activation of JUN kinase activity IEA GO:0007275 multicellular organismal development IEA GO:0009314 response to radiation IEA GO:0009887 organ morphogenesis IEA GO:0010740 positive regulation of intracellular protein kinase cascade IDA GO:0019221 cytokine-mediated signaling pathway IDA GO:0030154 cell differentiation IEA GO:0030316 osteoclast differentiation IDA GO:0030316 osteoclast differentiation ISS GO:0030316 osteoclast differentiation NAS GO:0033209 tumor necrosis factor-mediated signaling pathway ISS GO:0033598 mammary gland epithelial cell proliferation IEA GO:0034112 positive regulation of homotypic cell-cell adhesion IDA GO:0042327 positive regulation of phosphorylation IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0045672 positive regulation of osteoclast differentiation IDA GO:0045780 positive regulation of bone resorption IDA GO:0050870 positive regulation of T cell activation IDA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity ISS GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051260 protein homooligomerization IEA GO:0051466 positive regulation of corticotropin-releasing hormone secretion ISS GO:0051897 positive regulation of protein kinase B signaling cascade IEA GO:0060749 mammary gland alveolus development IEA GO:0070371 ERK1 and ERK2 cascade IEA GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion ISS GO:0071847 TNFSF11-mediated signaling pathway IDA GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling IDA cellular_component GO:0005576 extracellular region NAS GO:0005615 extracellular space IEA GO:0005622 intracellular IEA GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IEA GO:0005887 integral to plasma membrane NAS molecular_function GO:0004872 receptor activity IEA GO:0005125 cytokine activity IDA GO:0005125 cytokine activity NAS GO:0005164 tumor necrosis factor receptor binding NAS GO:0032813 tumor necrosis factor receptor superfamily binding IC

Protein-protein interaction details for TNFSF11 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SRC Affinity Capture-Western physical 10635328 KHDRBS1 Biochemical Activity physical 10635328 TNFRSF11B Reconstituted Complex physical 9520411 ZNF675 Phenotypic Suppression genetic 11751921 PLK1 Two-hybrid physical 21900206 DDAH2 Two-hybrid physical 21900206 C1orf93 Two-hybrid physical 21900206 TMOD3 Two-hybrid physical 21900206 LMO4 Two-hybrid physical 21900206 TRMT2A Two-hybrid physical 21900206 MED24 Two-hybrid physical 21900206 BBS10 Two-hybrid physical 21900206 SNRNP35 Two-hybrid physical 21900206 KIAA1377 Two-hybrid physical 21900206 SBF1 Two-hybrid physical 21900206 PHAX Two-hybrid physical 21900206 MBTPS1 Two-hybrid physical 21900206 EEF1A1 Two-hybrid physical 21900206 ZC3HC1 Two-hybrid physical 21900206 EZH2 Two-hybrid physical 21900206