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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CBLB (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002669 positive regulation of T cell anergy IEA GO:0006607 NLS-bearing substrate import into nucleus TAS GO:0006955 immune response IEA GO:0007165 signal transduction TAS GO:0007166 cell surface receptor linked signaling pathway IEA GO:0009629 response to gravity IEA GO:0009725 response to hormone stimulus IEA GO:0023051 regulation of signaling IEA GO:0035556 intracellular signal transduction IEA GO:0042110 T cell activation IEA GO:0045732 positive regulation of protein catabolic process IEA GO:0046642 negative regulation of alpha-beta T cell proliferation IEA GO:0050860 negative regulation of T cell receptor signaling pathway IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0045121 membrane raft IEA molecular_function GO:0001784 phosphotyrosine binding IEA GO:0004842 ubiquitin-protein ligase activity IEA GO:0004871 signal transducer activity IEA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0016874 ligase activity IEA GO:0019901 protein kinase binding IEA

Protein-protein interaction details for CBLB (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GORASP2 Two-hybrid physical 16189514 CRY1 Two-hybrid physical 16189514 NCK2 Two-hybrid physical 16189514 SORBS3 Two-hybrid physical 16189514 EGFR Affinity Capture-MS physical 16729043 NEDD4 Reconstituted Complex physical 12907674 NEDD4 Affinity Capture-Western physical 12907674 NEDD4 Affinity Capture-Western physical 12907674 ZAP70 Affinity Capture-Western physical 10074432 EGFR Affinity Capture-Western physical 10086340 GRB2 Affinity Capture-Western physical 10086340 SHC1 Affinity Capture-Western physical 9614102 GRB2 Affinity Capture-Western physical 9614102 PIK3R1 Affinity Capture-Western physical 9614102 GRB2 Reconstituted Complex physical 9614102 VAV1 Affinity Capture-Western physical 11857085 BTK Affinity Capture-Western physical 12093870 PLCG2 Affinity Capture-Western physical 12093870 SH3KBP1 Two-hybrid physical 12177062 SH3KBP1 Affinity Capture-Western physical 12177062 SH3KBP1 Affinity Capture-Western physical 12177062 KIT Affinity Capture-Western physical 12177062 SYK Affinity Capture-Western physical 10022120 GRB2 Affinity Capture-Western physical 10022120 CRKL Affinity Capture-Western physical 10022120 PIK3R1 Affinity Capture-Western physical 10022120 PIK3R1 Affinity Capture-Western physical 10022120 CRKL Affinity Capture-Western physical 10022120 IRS1 Affinity Capture-Western physical 16734387 GRB2 Two-hybrid physical 20936779 EGFR Affinity Capture-Western physical 16702950 EGFR Affinity Capture-Western physical 16702950 UBC Reconstituted Complex physical 19880507 CARD11 Affinity Capture-Western physical 19815501 CARD11 Affinity Capture-Western physical 19815501 EGFR Affinity Capture-MS physical 19531499 GRB2 Two-hybrid physical 21900206