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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IQGAP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006112 energy reserve metabolic process TAS GO:0007165 signal transduction IEA GO:0043547 positive regulation of GTPase activity TAS GO:0050796 regulation of insulin secretion TAS GO:0051056 regulation of small GTPase mediated signal transduction IEA cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005884 actin filament TAS GO:0005886 plasma membrane IDA GO:0005911 cell-cell junction IEA GO:0016020 membrane TAS GO:0016328 lateral plasma membrane IEA GO:0030496 midbody IDA GO:0031252 cell leading edge IEA GO:0043005 neuron projection IEA molecular_function GO:0005095 GTPase inhibitor activity TAS GO:0005096 GTPase activator activity TAS GO:0005099 Ras GTPase activator activity IEA GO:0005515 protein binding IPI GO:0005516 calmodulin binding IEA GO:0019903 protein phosphatase binding IPI GO:0048365 Rac GTPase binding IEA

Protein-protein interaction details for IQGAP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ARF6 Affinity Capture-MS physical 17353931 PRKACA Co-purification physical 12938160 PRKACA Affinity Capture-Western physical 12938160 AKAP5 Reconstituted Complex physical 12938160 GRB2 Affinity Capture-MS physical 12577067 CALM1 Reconstituted Complex physical 12446675 S100B Affinity Capture-Western physical 12377780 S100B Reconstituted Complex physical 12377780 CDC42 Reconstituted Complex physical 8798539 RAC1 Reconstituted Complex physical 8798539 CDC42 Affinity Capture-Western physical 8798539 CLIP1 Affinity Capture-Western physical 12110184 CLIP1 Reconstituted Complex physical 12110184 RAC1 Affinity Capture-Western physical 12110184 CDC42 Affinity Capture-Western physical 12110184 EZR Reconstituted Complex physical 10793131 CTNNB1 Reconstituted Complex physical 11734550 CALM1 Reconstituted Complex physical 11734550 CDH1 Affinity Capture-Western physical 10608854 CDH1 Reconstituted Complex physical 10608854 CDC42 Reconstituted Complex physical 8670801 CDC42 Affinity Capture-Western physical 8670801 RAC1 Affinity Capture-Western physical 8670801 CDC42 Reconstituted Complex physical 9182573 RAC1 Reconstituted Complex physical 9535855 CDC42 Reconstituted Complex physical 9535855 USP46 Affinity Capture-MS physical 19615732 KBTBD7 Affinity Capture-MS physical 20562859 PPARGC1A Affinity Capture-MS physical 17050673 MYL6B Affinity Capture-Western physical 21428964 YWHAQ Affinity Capture-MS physical 15161933 SUMO1 Affinity Capture-MS physical 19596686 SUMO1 Reconstituted Complex physical 19596686 UBC Affinity Capture-MS physical 20639865 UBC Affinity Capture-MS physical 18781797