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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CCNB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000079 regulation of cyclin-dependent protein kinase activity IEA GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000086 G2/M transition of mitotic cell cycle NAS GO:0000086 G2/M transition of mitotic cell cycle TAS GO:0000236 mitotic prometaphase IDA GO:0000278 mitotic cell cycle TAS GO:0001556 oocyte maturation IEA GO:0001701 in utero embryonic development IEA GO:0001933 negative regulation of protein phosphorylation IEA GO:0006461 protein complex assembly IEA GO:0007080 mitotic metaphase plate congression IMP GO:0007283 spermatogenesis IEA GO:0009612 response to mechanical stimulus IEA GO:0009636 response to toxin IEA GO:0010629 negative regulation of gene expression IEA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0031442 positive regulation of mRNA 3'-end processing IEA GO:0033129 positive regulation of histone phosphorylation IEA GO:0042246 tissue regeneration IEA GO:0042493 response to drug IEA GO:0043148 mitotic spindle stabilization IMP GO:0045931 positive regulation of mitotic cell cycle IMP GO:0046680 response to DDT IEA GO:0048565 digestive tract development IEA GO:0051301 cell division IEA GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore IMP GO:0055015 ventricular cardiac muscle cell development IEA GO:0060045 positive regulation of cardiac muscle cell proliferation IEA GO:0060623 regulation of chromosome condensation IEA GO:0071174 mitotic cell cycle spindle checkpoint IMP GO:0071283 cellular response to iron(III) ion IEA GO:0071398 cellular response to fatty acid IEA GO:0071407 cellular response to organic cyclic compound IEA GO:0071456 cellular response to hypoxia IEA cellular_component GO:0000922 spindle pole IDA GO:0000942 condensed nuclear chromosome outer kinetochore IDA GO:0005624 membrane fraction IEA GO:0005625 soluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005815 microtubule organizing center IEA GO:0005829 cytosol TAS GO:0005856 cytoskeleton IEA molecular_function GO:0005515 protein binding IPI GO:0016301 kinase activity IEA GO:0019901 protein kinase binding IEA GO:0035173 histone kinase activity IEA

Protein-protein interaction details for CCNB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RALBP1 Two-hybrid physical 12775724 GADD45A Reconstituted Complex physical 10362260 RALBP1 Reconstituted Complex physical 12775724 RALBP1 Affinity Capture-Western physical 12775724 CDK2 Affinity Capture-Western physical 9891079 CDK1 Affinity Capture-Western physical 9891079 HERC5 Reconstituted Complex physical 10581175 CDK1 Affinity Capture-Western physical 10973963 CDC25A Affinity Capture-Western physical 1836978 TGFBR2 Reconstituted Complex physical 9926943 BRCA1 Reconstituted Complex physical 9244350 CDK1 Affinity Capture-Western physical 2570636 CDC25C Reconstituted Complex physical 10864927 GADD45A Reconstituted Complex physical 12124778 GADD45B Reconstituted Complex physical 12124778 GADD45G Reconstituted Complex physical 12124778 CDK1 Affinity Capture-Western physical 10716937 CCNF Affinity Capture-Western physical 10716937 CDKN1A Affinity Capture-Western physical 17679094 CDK1 Affinity Capture-Western physical 17679094 HIST1H1A Affinity Capture-Western physical 9247342 CDK1 Reconstituted Complex physical 9247342 CDK1 Affinity Capture-Western physical 16784539 CDC14A Affinity Capture-Western physical 16784539 ZC3HC1 Reconstituted Complex physical 17389604 PSMD4 Reconstituted Complex physical 16799550 RAD23A Reconstituted Complex physical 16799550 UBQLN1 Reconstituted Complex physical 16799550 CDC27 Affinity Capture-Western physical 16479161 ZC3HC1 Affinity Capture-Western physical 16009132 UBC Affinity Capture-Western physical 16009132 UBC Affinity Capture-Western physical 15256223 TSPYL2 Affinity Capture-Western physical 18591933 TSPYL2 Reconstituted Complex physical 18591933 GAPDH Reconstituted Complex physical 16474839 GAPDH Affinity Capture-Western physical 16474839 SET Affinity Capture-Western physical 16474839 MGMT Affinity Capture-Western physical 16226712 CDK1 Affinity Capture-Western physical 16159883 CDKN1A Reconstituted Complex physical 16082198 UBC Affinity Capture-Western physical 12097298 CDC27 Affinity Capture-Western physical 12097298 FOXM1 Affinity Capture-Western physical 15024056 CDK1 Affinity Capture-Western physical 20228808 ARID4A Biochemical Activity physical 21148318 CDK1 Affinity Capture-Western physical 20367638 UBC Affinity Capture-Western physical 20367638 UBC Affinity Capture-Western physical 18059335 ANAPC1 Biochemical Activity physical 20080579 ANAPC2 Biochemical Activity physical 20080579 CDC27 Biochemical Activity physical 20080579 ANAPC4 Biochemical Activity physical 20080579 ANAPC5 Biochemical Activity physical 20080579 CDC16 Biochemical Activity physical 20080579 ANAPC7 Biochemical Activity physical 20080579 CDC23 Biochemical Activity physical 20080579 ANAPC16 Biochemical Activity physical 20080579 ANAPC10 Biochemical Activity physical 20080579 ANAPC11 Biochemical Activity physical 20080579 CDC26 Biochemical Activity physical 20080579 ANAPC13 Biochemical Activity physical 20080579 CDC20 Biochemical Activity physical 19820702 UHRF2 Far Western physical 21952639 UHRF2 Affinity Capture-Western physical 21952639 UHRF2 Affinity Capture-Western physical 21952639 UBC Reconstituted Complex physical 19475398 FBXO5 Biochemical Activity physical 19475398 CDKN1A Affinity Capture-Western physical 11559705 ANAPC1 Biochemical Activity physical 22193957 ANAPC2 Biochemical Activity physical 22193957 ANAPC4 Biochemical Activity physical 22193957 ANAPC5 Biochemical Activity physical 22193957 ANAPC7 Biochemical Activity physical 22193957 CDC16 Biochemical Activity physical 22193957 CDC23 Biochemical Activity physical 22193957 CDC27 Biochemical Activity physical 22193957 ANAPC2 Affinity Capture-Western physical 22193957 UBE2K Affinity Capture-Western physical 20965177 UBC Affinity Capture-Western physical 20965177 CDC20 Biochemical Activity physical 20383333 CDH1 Biochemical Activity physical 20383333 FZR1 Reconstituted Complex physical 14701726 CDC20 Reconstituted Complex physical 14701726 UBE2CBP Reconstituted Complex physical 15749827 UBE2CBP Biochemical Activity physical 15749827 CDK2 Affinity Capture-Western physical 20733051