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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PIAS2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0016925 protein sumoylation IEA GO:0030521 androgen receptor signaling pathway NAS GO:0045667 regulation of osteoblast differentiation IEA GO:0045893 positive regulation of transcription, DNA-dependent NAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0060766 negative regulation of androgen receptor signaling pathway IDA cellular_component GO:0005634 nucleus IDA GO:0016605 PML body IEA GO:0016607 nuclear speck IEA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003713 transcription coactivator activity NAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0019789 SUMO ligase activity IDA GO:0031625 ubiquitin protein ligase binding IEA GO:0046872 metal ion binding IEA GO:0050681 androgen receptor binding NAS

Protein-protein interaction details for PIAS2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID AR Two-hybrid physical 11117529 AR Two-hybrid physical 9920921 NAV2 Two-hybrid physical 16189514 UBE2I Two-hybrid physical 16189514 DNMT3A Two-hybrid physical 14752048 DNMT3A Affinity Capture-Western physical 14752048 DNMT3A Affinity Capture-Western physical 14752048 DNMT3A Reconstituted Complex physical 14752048 UBE2I Two-hybrid physical 14609633 SUMO1 Two-hybrid physical 14609633 STAT4 Affinity Capture-Western physical 12716907 MYC Affinity Capture-Western physical 11283613 AR Reconstituted Complex physical 9920921 AR Reconstituted Complex physical 11117529 ESR1 Reconstituted Complex physical 11117529 ESR2 Reconstituted Complex physical 11117529 NR3C1 Reconstituted Complex physical 11117529 PGR Reconstituted Complex physical 11117529 GTF2IRD1 Reconstituted Complex physical 12193603 PARK7 Two-hybrid physical 11477070 PARK7 Reconstituted Complex physical 11477070 PARK7 Affinity Capture-Western physical 11477070 ITGB5 Two-hybrid physical 12356872 MYC Affinity Capture-Western physical 18923429 SIAH1 Two-hybrid physical 17533377 SIAH2 Two-hybrid physical 17533377 AKT1 Two-hybrid physical 17533377 HUWE1 Reconstituted Complex physical 16269333 HUWE1 Affinity Capture-Western physical 16269333 UBE2I Two-hybrid physical 20936779 GLUL Two-hybrid physical 20936779 SREBF2 Two-hybrid physical 20936779 MITF Reconstituted Complex physical 16029420 MITF Reconstituted Complex physical 16029420 CDKN2A Two-hybrid physical 19901969 CDKN2A Affinity Capture-Western physical 19901969 CDKN2A Affinity Capture-Western physical 19901969 TP53 Affinity Capture-Western physical 19901969 TP53 Affinity Capture-Western physical 19901969 MBD1 Two-hybrid physical 17066076 MBD1 Reconstituted Complex physical 17066076 SUMO2 Affinity Capture-MS physical 19394292 TRIM27 Affinity Capture-Western physical 15907835 TRIM27 Two-hybrid physical 15907835 ZBTB4 Affinity Capture-Western physical 18451802 UBE2I Reconstituted Complex physical 11867732 TP53 Reconstituted Complex physical 11867732 SUMO1 Reconstituted Complex physical 11867732 JUN Reconstituted Complex physical 11867732 TP53 Reconstituted Complex physical 11867732 MYC Affinity Capture-Western physical 17471507 MYC Affinity Capture-Western physical 17418410 MYC Affinity Capture-Western physical 17418410 HIC1 Biochemical Activity physical 17283066 MYC Affinity Capture-Western physical 20426839 MYC Affinity Capture-Western physical 20426839 NTRK1 Affinity Capture-RNA physical 21123453 NGFR Affinity Capture-RNA physical 21123453 MYCN Affinity Capture-Western physical 21123453 MYCN Reconstituted Complex physical 21123453 NEDD8 Affinity Capture-MS physical 18274552 UBC Reconstituted Complex physical 20624960 HUWE1 Biochemical Activity physical 20624960 HUWE1 Affinity Capture-Western physical 20624960 UBC Affinity Capture-Western physical 20624960 MAPK8 Affinity Capture-MS physical 19815509 MAPK8 Affinity Capture-Western physical 19815509 MAPK8 Two-hybrid physical 19815509 MAPK8 Reconstituted Complex physical 19815509 TP53 Two-hybrid physical 18624398 TRAF2 Reconstituted Complex physical 22184250 TRAF2 Affinity Capture-Western physical 22184250 TRAF2 Affinity Capture-Western physical 22184250 UBC Affinity Capture-Western physical 22184250 UBC Affinity Capture-MS physical 22184250 PML Co-localization physical 21779164 IFIH1 Affinity Capture-Western physical 21156324 IFIH1 Affinity Capture-Western physical 21156324